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A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein

artículo científico publicado en 2019

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

artículo científico publicado en 2019

ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators

scientific article published on 27 November 2019

Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein

artículo científico publicado en 2017

Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1)

artículo científico publicado en 2018

Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein

scientific article published in Scientific Reports

Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles

artículo científico publicado en 2021

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

artículo científico publicado en 2020

Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

scientific article published on 07 January 2020

P-glycoprotein Mediates Resistance to the Anaplastic Lymphoma Kinase Inhiitor Ensartinib in Cancer Cells

artículo científico publicado en 2022

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein

artículo científico publicado en 2020

Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance-Linked ATP-Binding Cassette Transporter ABCG2.

artículo científico publicado en 2017

Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance

scientific article published on 12 January 2020

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