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A Novel YAP1 Inhibitor targets CSCs-enriched Radiation Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma.

artículo científico publicado en 2017

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer

artículo científico publicado en 2015

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue

scientific article published on 13 February 2020

Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors

artículo científico publicado en 2017

LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma

artículo científico publicado en 2020

LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

scientific article published on 10 October 2019

PPARδ Interacts with the Hippo Coactivator YAP1 to Promote SOX9 Expression and Gastric Cancer Progression

artículo científico publicado en 2019

Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma

scientific article published on 16 March 2020

The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer

artículo científico publicado en 2015

YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition

scientific article published on 27 April 2020

YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer

artículo científico publicado en 2018

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