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A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach

artículo científico publicado en 2021

A distinct difference in the metabolic stimulus–response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties ⬇️

artículo científico publicado el 15 de abril de 1998

Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats ⬇️

artículo científico publicado el 1 de mayo de 2003

Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

scientific article published on 30 June 2020

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation ⬇️

artículo científico publicado el 1 de marzo de 1998

Decreasing IRS-2 expression in pancreatic β-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression ⬇️

artículo científico publicado el 14 de noviembre de 2003

FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes ⬇️

artículo científico publicado el 20 de septiembre de 2011

Genetic determinants of risk and survival in pulmonary arterial hypertension

article

How is the insulin content regulated in nondiabetic hyperinsulinaemic, insulin resistant states? Study of spontaneously hypertensive rats ⬇️

artículo científico publicado el 1 de julio de 1998

Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

artículo científico publicado en 2018

Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension

scientific article published on 12 February 2020

Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study.

artículo científico publicado en 2017

Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-Cells ⬇️

artículo científico publicado el 22 de septiembre de 2011

Targeting Vessel Formation in Pulmonary Arterial Hypertension: Is the Endostatin-Id1-Thrombospondin 1 Pathway a New Hope?

scientific article published on 01 April 2020

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

artículo científico publicado en 2020

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