Lista de obras -

A licensing step links AID to transcription elongation for mutagenesis in B cells

artículo científico publicado en 2018

A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling

artículo científico publicado en 2005

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs

artículo científico publicado en 2021

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

artículo científico publicado en 2020

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer

article

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling

artículo científico publicado en 2008

An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling

artículo científico publicado en 2010

Author Correction: Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

artículo científico publicado en 2020

Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion

artículo científico publicado en 2014

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.

artículo científico publicado en 2017

Cell biology. Two lipids that give direction

artículo científico publicado en 2009

ClipR-59 interacts with Elmo2 and modulates myoblast fusion

artículo científico publicado en 2015

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

artículo científico publicado en 2010

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

artículo científico publicado en 2014

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

artículo científico publicado en 2014

ELMO Recruits Actin Cross-linking Family 7 (ACF7) at the Cell Membrane for Microtubule Capture and Stabilization of Cellular Protrusions ⬇️

artículo científico publicado el 26 de noviembre de 2012

Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation.

artículo científico publicado en 2016

Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development

artículo científico publicado en 2006

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting ⬇️

artículo científico publicado el 30 de agosto de 2012

G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates

artículo científico publicado en 2014

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

artículo científico publicado en 2007

GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.

artículo científico publicado en 2018

GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

artículo científico publicado en 2021

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes

artículo científico publicado en 2019

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

artículo científico publicado en 2018

Insights into the biological functions of Dock family guanine nucleotide exchange factors

artículo científico

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

artículo científico publicado en 2019

NSCLC metastasis: going with ELMO3.

artículo científico publicado en 2014

Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis

artículo científico publicado en 2016

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

artículo científico publicado en 2020

Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex

artículo científico publicado en 2011

Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis

artículo científico publicado en 2010

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation

artículo científico publicado en 2013

Polarized Dock Activity Drives Shh-Mediated Axon Guidance

scientific article published on 02 August 2018

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

artículo científico publicado en 2013

Rac1 activation in podocytes induces the spectrum of nephrotic syndrome

artículo científico publicado en 2017

Ras GTPases' interaction with effector domains: Breaking the families' barrier

artículo científico publicado en 2013

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice

artículo científico publicado en 2018

Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression

artículo científico publicado en 2020

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

artículo científico publicado en 2018

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state

artículo científico publicado en 2020

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

artículo científico publicado en 2017

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family

artículo científico publicado en 2011

The E3 Ubiquitin Ligase HectD1 Suppresses EMT and Metastasis by Targeting the +TIP ACF7 for Degradation

artículo científico publicado en 2018

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo

artículo científico publicado en 2013

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

artículo científico publicado en 2018

The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance

artículo científico publicado en 2019

Lista de obras de

A licensing step links AID to transcription elongation for mutagenesis in B cells

A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling

An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling

Author Correction: Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.

Cell biology. Two lipids that give direction

ClipR-59 interacts with Elmo2 and modulates myoblast fusion

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

ELMO Recruits Actin Cross-linking Family 7 (ACF7) at the Cell Membrane for Microtubule Capture and Stabilization of Cellular Protrusions ⬇️

Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation.

Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1–induced collective directional migration and angiogenic sprouting ⬇️

G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.

GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

Insights into the biological functions of Dock family guanine nucleotide exchange factors

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

NSCLC metastasis: going with ELMO3.

Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

Opening up on ELMO regulation: New insights into the control of Rac signaling by the DOCK180/ELMO complex

Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation

Polarized Dock Activity Drives Shh-Mediated Axon Guidance

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

Rac1 activation in podocytes induces the spectrum of nephrotic syndrome

Ras GTPases' interaction with effector domains: Breaking the families' barrier

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice

Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family

The E3 Ubiquitin Ligase HectD1 Suppresses EMT and Metastasis by Targeting the +TIP ACF7 for Degradation

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance