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2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist

artículo científico publicado en 2017

2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells

artículo científico publicado en 2023

3,17β-Bis-sulfamoyloxy-2-methoxyestra-1,3,5(10)-triene and Nonsteroidal Sulfamate Derivatives Inhibit Carbonic Anhydrase IX: Structure-Activity Optimization for Isoform Selectivity

scientific article published on 18 February 2019

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

scientific article published on 19 September 2018

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

artículo científico publicado en 2022

Accessing simply-substituted 4-hydroxytetrahydroisoquinolines via Pomeranz-Fritsch-Bobbitt reaction with non-activated and moderately-activated systems.

artículo científico publicado en 2017

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.

artículo científico publicado en 2017

Rapid and Efficient Microwave-Assisted Friedländer Quinoline Synthesis

artículo científico publicado en 2020

SHIP2: Structure, Function and Inhibition

artículo científico publicado en 2016

Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid "L-cyclic inosine 5'-diphosphate ribose".

artículo científico publicado en 2017

Small Molecule Antagonists of NAADP-Induced Ca Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease

artículo científico publicado en 2018

Synthesis of Terminal Ribose Analogues of Adenosine 5'-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2

artículo científico publicado en 2019

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7

scientific article published on 07 June 2019

Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers

artículo científico publicado en 2018

The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

scientific article published on 28 October 2020

d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities

artículo científico publicado en 2020

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