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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

artículo científico publicado en 2016

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

artículo científico publicado en 2018

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

artículo científico publicado en 1995

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

artículo científico publicado en 1999

A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies

artículo científico publicado en 2013

Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

artículo científico publicado en 2018

Aging and neurodegeneration are associated with increased mutations in single human neurons.

artículo científico publicado en 2017

An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation

artículo científico publicado en 2003

Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen

artículo científico publicado en 2006

Automated migration analysis based on cell texture: method & reliability

artículo científico publicado en 2005

BH3 domains: intracellular death-ligands critical for initiating apoptosis

artículo científico publicado en 2002

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

artículo científico publicado en 1999

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

artículo científico publicado en 1998

Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins

artículo científico publicado en 1995

Cell types differ in global coordination of splicing and proportion of highly expressed genes

artículo científico publicado en 2016

Characterization of synectin expression and promoter activity

artículo científico publicado en 2004

Chronic mTOR activation induces a degradative smooth muscle cell phenotype

artículo científico publicado en 2020

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium

scientific article published on 13 June 2019

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

artículo científico publicado en 2019

Enhancing Retrosynthetic Reaction Prediction with Deep Learning Using Multiscale Reaction Classification

scientific article published on 01 February 2019

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

artículo científico publicado en 2001

FGF-dependent metabolic control of vascular development

artículo científico publicado en 2017

Functional classification analysis of somatically mutated genes in human breast and colorectal cancers

artículo científico publicado en 2008

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

artículo científico publicado en 2003

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

artículo científico publicado en 2000

IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors

artículo científico publicado en 2015

In silico phenotype projection of endothelial ERK1/2 signaling

artículo científico publicado en 2020

Induction of apoptosis by the Bcl-2 homologue Bak

artículo científico publicado en 1995

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment

artículo científico publicado en 2018

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

artículo científico publicado en 2014

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

artículo científico publicado el 1 de octubre de 2003

Resilience, disease and the age of single cell science

scientific article published on 10 February 2020

SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies

artículo científico publicado en 2014

Science and technology consortia in U.S. biomedical research: A paradigm shift in response to unsustainable academic growth

artículo científico publicado en 2014

Selective regulation of arterial branching morphogenesis by synectin

artículo científico publicado en 2006

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

artículo científico publicado en 2017

Smooth Muscle Cell Reprogramming in Aortic Aneurysms

artículo científico publicado en 2020

Somatic mutation in single human neurons tracks developmental and transcriptional history

artículo científico publicado en 2015

Synectin-dependent gene expression in endothelial cells.

artículo científico

Synectin/syndecan-4 regulate coronary arteriolar growth during development

artículo científico publicado en 2007

Therapeutic implications of GIPC1 silencing in cancer

artículo científico publicado en 2010

Transcriptional Profiling in Coronary Artery Disease

scholarly article by Thomas W. Chittenden et al published 24 October 2006 in Circulation

Unique cardiopulmonary exercise test responses in overweight middle-aged adults with obstructive sleep apnea

artículo científico publicado en 2007

ei24, a p53 response gene involved in growth suppression and apoptosis

artículo científico publicado en 2000

nEASE: a method for gene ontology subclassification of high-throughput gene expression data.

artículo científico publicado en 2012

p53 has a direct apoptogenic role at the mitochondria

artículo científico publicado en 2003