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A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation

artículo científico publicado en 2003

Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice

artículo científico publicado en 2016

Ablation of glutaredoxin-1 attenuates lipopolysaccharide-induced lung inflammation and alveolar macrophage activation

artículo científico publicado en 2010

Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice

artículo científico publicado en 2016

Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation

artículo científico publicado en 2014

Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling

artículo científico publicado en 2011

Airway epithelial NF-κB activation promotes allergic sensitization to an innocuous inhaled antigen

artículo científico publicado en 2010

Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses

artículo científico publicado en 2015

Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways

artículo científico publicado en 2010

Biochemistry of asthma

artículo científico publicado en 2011

Catalase overexpression fails to attenuate allergic airways disease in the mouse

artículo científico publicado en 2007

Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death.

artículo científico publicado en 2011

Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells.

artículo científico publicado en 2012

DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma

artículo científico publicado en 2016

Differential requirement for c-Jun N-terminal kinase 1 in lung inflammation and host defense

artículo científico publicado en 2012

Distinct functions of airway epithelial nuclear factor-kappaB activity regulate nitrogen dioxide-induced acute lung injury

artículo científico publicado en 2009

Dual Oxidase–1 Is Required for Airway Epithelial Cell Migration and Bronchiolar Reepithelialization after Injury

artículo científico publicado el 13 de diciembre de 2012

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

artículo científico publicado en 2006

Effect of heart failure on the regulation of skeletal muscle protein synthesis, breakdown, and apoptosis

scientific article published on 11 February 2003

Emerging mechanisms of glutathione-dependent chemistry in biology and disease

artículo científico publicado en 2013

Enhanced myogenic differentiation by extracellular matrix is regulated at the early stages of myogenesis

artículo científico publicado el 1 de marzo de 2003

Eosinophil peroxidase catalyzes JNK-mediated membrane blebbing in a Rho kinase-dependent manner

artículo científico publicado en 2003

Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection.

artículo científico publicado en 2017

Epithelial NF-κB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling

artículo científico publicado en 2013

Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease

artículo científico publicado el 29 de junio de 2012

Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia.

scientific article published on February 2014

Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells

artículo científico publicado en 2016

Hydrogen peroxide as a damage signal in tissue injury and inflammation: murderer, mediator, or messenger?

artículo científico publicado en 2014

Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase

artículo científico publicado en 2003

Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells

scientific article published on 15 January 2014

In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1-catalyzed cysteine derivatization.

artículo científico publicado en 2009

In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation

artículo científico publicado en 2004

In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization.

artículo científico publicado en 2006

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

artículo científico publicado en 2013

Induction of a mesenchymal expression program in lung epithelial cells by wingless protein (Wnt)/β-catenin requires the presence of c-Jun N-terminal kinase-1 (JNK1).

artículo científico publicado en 2012

Influenza Induces Endoplasmic Reticulum Stress, Caspase-12–Dependent Apoptosis, and c-Jun N-Terminal Kinase–Mediated Transforming Growth Factor–β Release in Lung Epithelial Cells

artículo científico publicado el 28 de julio de 2011

Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration

artículo científico publicado en 2008

Inhibition of glycogen synthase kinase-3beta activity is sufficient to stimulate myogenic differentiation

artículo científico publicado en 2005

Inhibition of nuclear factor-κB in the lungs prevents monocrotaline-induced pulmonary hypertension in mice

artículo científico publicado en 2014

JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers.

artículo científico publicado en 2016

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1

artículo científico publicado en 2008

Modulation of NF-κB and Hypoxia-Inducible Factor−1 byS-Nitrosoglutathione Does Not Alter Allergic Airway Inflammation in Mice

artículo científico publicado el 6 de agosto de 2010

Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease

artículo científico publicado en 2006

Molecular mechanisms of nitrogen dioxide induced epithelial injury in the lung

artículo científico publicado en 2002

Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation

artículo científico publicado en 2006

Myogenic differentiation during regrowth of atrophied skeletal muscle is associated with inactivation of GSK-3beta

artículo científico publicado en 2006

NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness

artículo científico publicado en 2004

Nitric oxide and redox signaling in allergic airway inflammation

artículo científico publicado en 2005

Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation

artículo científico publicado en 2004

Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse

artículo científico publicado en 2005

Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis

artículo científico publicado en 2006

Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control

artículo científico publicado en 2009

Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness

artículo científico publicado en 2008

Oxidants are not all created equal: could hydrogen peroxide actually be good for our lungs?

artículo científico publicado en 2009

Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis

artículo científico publicado en 2012

Oxidative-nitrosative stress and post-translational protein modifications: implications to lung structure-function relations. Arginase modulates NF-kappaB activity via a nitric oxide-dependent mechanism

artículo científico publicado en 2007

Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness

artículo científico publicado en 2015

Protocols for the detection of s-glutathionylated and s-nitrosylated proteins in situ

artículo científico publicado en 2010

Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation

artículo científico publicado en 2002

Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium

artículo científico publicado en 2002

Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide

artículo científico publicado en 2003

Reactive nitrogen species in refractory asthma: markers or players?

artículo científico publicado en 2008

Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase

artículo científico publicado en 2004

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

artículo científico publicado en 2009

Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death

artículo científico publicado en 2012

Redox-based regulation of signal transduction: principles, pitfalls, and promises

artículo científico publicado en 2008

Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway

artículo científico publicado en 2006

Reducing protein oxidation reverses lung fibrosis

scientific article published on 09 July 2018

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.

artículo científico publicado en 2010

Rust never sleeps: The continuing story of the Iron Bolt

scientific article published on 18 June 2018

S-Glutathionylation of estrogen receptor alpha affects dendritic cell function.

artículo científico publicado en 2018

SOD inactivation in asthma: bad or no news?

artículo científico publicado en 2005

Strain-dependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation

artículo científico publicado en 2010

TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a JNK1-dependent manner.

artículo científico publicado en 2018

The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κB family proteins

artículo científico publicado en 2014

The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells.

artículo científico publicado en 2016

The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies

artículo científico publicado en 2017

Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma

artículo científico publicado en 2015

Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease

artículo científico publicado en 2007

Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways

artículo científico publicado en 2002

Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization

artículo científico publicado en 2004

c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis

artículo científico publicado en 2008

c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3.

artículo científico publicado en 2010