Lista de obras -

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

artículo científico publicado en 2019

5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study

artículo científico publicado en 2015

A Combination of Grape Extract, Green Tea Extract and l‐Carnitine Improves High‐fat Diet‐induced Obesity, Hyperlipidemia and Non‐alcoholic Fatty Liver Disease in Mice ⬇️

artículo científico publicado el 8 de abril de 2011

Acetylaminofluorene inhibits nitric oxide production in LPS-stimulated RAW 264.7 cells by blocking NF-kappa B/Rel activation

artículo científico publicado en 1999

Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4 ⬇️

artículo científico publicado el 8 de junio de 2012

Adjuvant effect of a natural TLR4 ligand on dendritic cell-based cancer immunotherapy ⬇️

artículo científico publicado el 17 de septiembre de 2011

Adoptive immunotherapy of human gastric cancer with ex vivo expanded T cells ⬇️

artículo científico publicado el 30 de noviembre de 2010

An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles

artículo científico

Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls

artículo científico publicado en 2003

Artemisinin inhibits lipopolysaccharide-induced interferon-β production in RAW 264.7 cells: Implications on signal transducer and activator of transcription-1 signaling and nitric oxide production ⬇️

artículo científico publicado el 2 de octubre de 2012

B cell-activating factor is a novel diagnosis parameter for asthma

artículo científico

Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis

scientific article published on 30 January 2019

Bisphenol A and its substitutes regulate human B cell survival via Nrf2 expression

artículo científico publicado en 2020

Breast cancer cells evade paclitaxel-induced cell death by developing resistance to dasatinib

artículo científico publicado en 2016

Combination treatment of renal cell carcinoma with belinostat and 5-fluorouracil: a role for oxidative stress induced DNA damage and HSP90 regulated thymidine synthase

artículo científico publicado en 2014

Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp ⬇️

artículo científico publicado el 18 de octubre de 2012

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy)methyl)-N-hydroxybenzamides / propenamides as Histone Deacetylase Inhibitors and Antitumor Agents

artículo científico publicado en 2019

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents

artículo científico publicado en 2017

Determination of Penicillium griseofulvum-oriented pyripyropene A, a selective inhibitor of acyl-coenzyme A:cholesterol acyltransferase 2, in mouse plasma using liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic st

artículo científico publicado en 2018

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors

scientific article published on 18 September 2018

Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors

artículo científico publicado en 2014

Dokdolipids A-C, Hydroxylated Rhamnolipids from the Marine-Derived Actinomycete Actinoalloteichus hymeniacidonis ⬇️

scientific article published on 20 April 2019

Effusanin C inhibits inflammatory responses via blocking NF-κB and MAPK signaling in monocytes ⬇️

artículo científico publicado el 15 de noviembre de 2012

Evaluation of the pharmacokinetics and metabolism of a novel histone deacetylase inhibitor, KBH-A40, in rats

artículo científico publicado en 2010

Hepatoprotective effect of aged black garlic extract in rodents.

artículo científico publicado en 2014

Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and l-carnitine: Implications in cardiovascular and non-alcoholic fatty liver diseases ⬇️

artículo científico publicado el 2 de julio de 2011

In vitro metabolism of KBH-A40, a novel delta-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum

artículo científico publicado en 2008

Inhibition of TAK1 by kamebakaurin in dendritic cells ⬇️

artículo científico publicado el 15 de noviembre de 2012

Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells

artículo científico publicado en 2015

Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro

artículo científico publicado en 2012

N ′-[(E )-Arylidene]-2-(2,3-dihydro-3-oxo-4H -1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity

artículo científico publicado en 2018

New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity

scientific article published on 04 February 2020

New Ophiobolin Derivatives from the Marine Fungus Aspergillus flocculosus and Their Cytotoxicities against Cancer Cells ⬇️

scientific article published on 11 June 2019

NgR1 Expressed in P19 Embryonal Carcinoma Cells Differentiated by Retinoic Acid Can Activate STAT3.

artículo científico publicado en 2015

Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

scientific article published on 14 August 2019

Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis

artículo científico publicado en 2018

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

artículo científico publicado en 2013

Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028 ⬇️

artículo científico publicado en 2019

Phenotypic and Functional Maturation of Dendritic Cells Induced by Polysaccharide Isolated from Paecilomyces cicadae ⬇️

artículo científico publicado el 1 de julio de 2011

Plasma pharmacokinetics and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in rats

artículo científico publicado en 2009

Prevention of arthritic inflammation using an oriental herbal combination BDX-1 isolated from Achyranthes bidentata and Atractylodes japonica

artículo científico publicado en 2005

Property based optimization of δ-lactam HDAC inhibitors for metabolic stability ⬇️

artículo científico publicado el 17 de septiembre de 2010

Protective effect of silymarin against ethanol-induced gastritis in rats: Role of sulfhydryls, nitric oxide and gastric sensory afferents ⬇️

artículo científico publicado el 26 de enero de 2013

Protein kinase C stimulates human B cell activating factor gene expression through reactive oxygen species-dependent c-Fos in THP-1 pro-monocytic cells ⬇️

artículo científico publicado el 25 de abril de 2012

Quinazoline-based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

artículo científico publicado en 2018

Resorcinosides A and B, Glycosylated Alkylresorcinols from a Marine-Derived Strain of the Fungus Penicillium janthinellum

artículo científico publicado en 2019

Silymarin inhibits TNF-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells.

artículo científico publicado en 2003

Sophoricoside isolated from Sophora japonica ameliorates contact dermatitis by inhibiting NF-κB signaling in B cells ⬇️

artículo científico publicado el 14 de febrero de 2013

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors ⬇️

artículo científico publicado el 21 de diciembre de 2010

Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells

artículo científico publicado en 2015

Suppression of IL-8 gene expression by radicicol is mediated through the inhibition of ERK1/2 and p38 signaling and negative regulation of NF-kappaB and AP-1.

artículo científico publicado en 2001

Suppression of RANKL-Induced Osteoclastogenesis by the Metabolites from the Marine Fungus Aspergillus flocculosus Isolated from a Sponge Stylissa sp. ⬇️

artículo científico publicado en 2018

Synthesis and biological evaluation of novel thieno[2,3-d]pyrimidine-based FLT3 inhibitors as anti-leukemic agents

artículo científico publicado en 2014

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

artículo científico publicado en 2013

Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C2 and C6 positions

artículo científico publicado en 2016

Testing Cell-Based Immunotherapy for Colorectal Cancer

artículo científico publicado en 2018

Transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in Caco-2 cells

artículo científico publicado en 2009

Tussilagone inhibits dendritic cell functions via induction of heme oxygenase-1.

artículo científico publicado en 2014

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

artículo científico publicado en 2014

Violapyrones H and I, new cytotoxic compounds isolated from Streptomyces sp. associated with the marine starfish Acanthaster planci ⬇️

artículo científico publicado en 2014

Xylodon flaviporus-Derived Drimane Sesquiterpenoids That Inhibit Osteoclast Differentiation

scientific article published on 10 October 2019

Lista de obras de

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study

A Combination of Grape Extract, Green Tea Extract and l‐Carnitine Improves High‐fat Diet‐induced Obesity, Hyperlipidemia and Non‐alcoholic Fatty Liver Disease in Mice ⬇️

Acetylaminofluorene inhibits nitric oxide production in LPS-stimulated RAW 264.7 cells by blocking NF-kappa B/Rel activation

Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4 ⬇️

Adjuvant effect of a natural TLR4 ligand on dendritic cell-based cancer immunotherapy ⬇️

Adoptive immunotherapy of human gastric cancer with ex vivo expanded T cells ⬇️

An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles

Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls

Artemisinin inhibits lipopolysaccharide-induced interferon-β production in RAW 264.7 cells: Implications on signal transducer and activator of transcription-1 signaling and nitric oxide production ⬇️

B cell-activating factor is a novel diagnosis parameter for asthma

Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis

Bisphenol A and its substitutes regulate human B cell survival via Nrf2 expression

Breast cancer cells evade paclitaxel-induced cell death by developing resistance to dasatinib

Combination treatment of renal cell carcinoma with belinostat and 5-fluorouracil: a role for oxidative stress induced DNA damage and HSP90 regulated thymidine synthase

Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp ⬇️

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy)methyl)-N-hydroxybenzamides / propenamides as Histone Deacetylase Inhibitors and Antitumor Agents

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents

Determination of Penicillium griseofulvum-oriented pyripyropene A, a selective inhibitor of acyl-coenzyme A:cholesterol acyltransferase 2, in mouse plasma using liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic st

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors

Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors

Dokdolipids A-C, Hydroxylated Rhamnolipids from the Marine-Derived Actinomycete Actinoalloteichus hymeniacidonis ⬇️

Effusanin C inhibits inflammatory responses via blocking NF-κB and MAPK signaling in monocytes ⬇️

Evaluation of the pharmacokinetics and metabolism of a novel histone deacetylase inhibitor, KBH-A40, in rats

Hepatoprotective effect of aged black garlic extract in rodents.

Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and l-carnitine: Implications in cardiovascular and non-alcoholic fatty liver diseases ⬇️

In vitro metabolism of KBH-A40, a novel delta-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum

Inhibition of TAK1 by kamebakaurin in dendritic cells ⬇️

Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells

Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro

N ′-[(E )-Arylidene]-2-(2,3-dihydro-3-oxo-4H -1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity

New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity

New Ophiobolin Derivatives from the Marine Fungus Aspergillus flocculosus and Their Cytotoxicities against Cancer Cells ⬇️

NgR1 Expressed in P19 Embryonal Carcinoma Cells Differentiated by Retinoic Acid Can Activate STAT3.

Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028 ⬇️

Phenotypic and Functional Maturation of Dendritic Cells Induced by Polysaccharide Isolated from Paecilomyces cicadae ⬇️

Plasma pharmacokinetics and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in rats

Prevention of arthritic inflammation using an oriental herbal combination BDX-1 isolated from Achyranthes bidentata and Atractylodes japonica

Property based optimization of δ-lactam HDAC inhibitors for metabolic stability ⬇️

Protective effect of silymarin against ethanol-induced gastritis in rats: Role of sulfhydryls, nitric oxide and gastric sensory afferents ⬇️

Protein kinase C stimulates human B cell activating factor gene expression through reactive oxygen species-dependent c-Fos in THP-1 pro-monocytic cells ⬇️

Quinazoline-based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity

Resorcinosides A and B, Glycosylated Alkylresorcinols from a Marine-Derived Strain of the Fungus Penicillium janthinellum

Silymarin inhibits TNF-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells.

Sophoricoside isolated from Sophora japonica ameliorates contact dermatitis by inhibiting NF-κB signaling in B cells ⬇️

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors ⬇️

Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells

Suppression of IL-8 gene expression by radicicol is mediated through the inhibition of ERK1/2 and p38 signaling and negative regulation of NF-kappaB and AP-1.

Suppression of RANKL-Induced Osteoclastogenesis by the Metabolites from the Marine Fungus Aspergillus flocculosus Isolated from a Sponge Stylissa sp. ⬇️

Synthesis and biological evaluation of novel thieno[2,3-d]pyrimidine-based FLT3 inhibitors as anti-leukemic agents

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C2 and C6 positions

Testing Cell-Based Immunotherapy for Colorectal Cancer

Transport and metabolism of the antitumour drug candidate 2'-benzoyloxycinnamaldehyde in Caco-2 cells

Tussilagone inhibits dendritic cell functions via induction of heme oxygenase-1.

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

Violapyrones H and I, new cytotoxic compounds isolated from Streptomyces sp. associated with the marine starfish Acanthaster planci ⬇️

Xylodon flaviporus-Derived Drimane Sesquiterpenoids That Inhibit Osteoclast Differentiation