Lista de obras -

10

scientific article published in 2013

12

scientific article published in 2013

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

artículo científico publicado en 2009

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

artículo científico publicado en 2016

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

artículo científico publicado en 2019

A NOD for autophagy

scientific article published on 01 January 2010

A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.

artículo científico publicado en 2010

A functional genomics approach in Tanzanian population identifies distinct genetic regulators of cytokine production compared to European population

scientific article published in 2022

A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis

scientific article published in 2023

A guiding map for inflammation

artículo científico publicado en 2017

A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis

scientific article published on 13 January 2020

A limited role of cytokine storm and fibrogenesis in COVID-19 related liver injury

scientific article published in 2021

A modular approach toward producing nanotherapeutics targeting the innate immune system

scientific article published in 2021

A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist

artículo científico publicado en 2014

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome

scientific article published on 09 May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome

article

A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma

artículo científico publicado en 2013

A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis

artículo científico publicado en 2022

A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis.

artículo científico publicado en 2012

A role for TLR10 in obesity and adipose tissue morphology.

artículo científico publicado en 2018

A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

scientific article published in 2023

A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection

artículo científico publicado en 2020

ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation

artículo científico publicado en 2011

Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

artículo científico publicado en 2017

Absence of citrulline-specific autoantibodies in animal models of autoimmunity

artículo científico publicado en 2004

Abstract 19220: Hepatic Steatosis is Independently Associated With an Increased Vascular Stiffness in Overweight Subjects

scientific article published in 2015

Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers

scientific article published in 2022

Activation of innate host defense mechanisms by Borrelia

artículo científico publicado en 2010

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance

artículo científico publicado en 2016

Acute Cytokine Response During Breast Cancer Surgery: Potential Role of Dexamethasone and Lidocaine and Relationship with Postoperative Pain and Complications - Analysis of Three Pooled Pilot Randomized Controlled Trials

artículo científico publicado en 2020

Adaptation and memory in innate immunity

artículo científico publicado en 2016

Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction

scientific article published in 1999

Advances in understanding molecular regulation of innate immune memory

scientific article published on 25 January 2020

Aldosterone induces trained immunity: the role of fatty acid synthesis

artículo científico publicado en 2020

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

artículo científico publicado en 2015

Altered Ex-Vivo Cytokine Responses in Children With Asymptomatic Plasmodium falciparum Infection in Burkina Faso: An Additional Argument to Treat Asymptomatic Malaria?

scientific article published in 2021

Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines

artículo científico publicado en 2015

Amplifying elements of arthritis and joint destruction

artículo científico publicado en 2007

An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo

scientific article published in 2021

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism

artículo científico publicado en 2014

An integrative genomics approach identifies KDM4 as a modulator of trained immunity

artículo científico publicado en 2021

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

artículo científico publicado en 2017

An integrative model of cardiometabolic traits identifies two types of metabolic syndrome

artículo científico publicado en 2021

An observational study of innate immune responses in patients with acute appendicitis

artículo científico publicado en 2020

Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance

artículo científico publicado en 2011

Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity.

artículo científico publicado en 2009

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

scientific article published on 04 March 2019

Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra

scientific article published on 01 February 2008

Arterial Wall Inflammation and Increased Hematopoietic Activity in Patients With Primary Aldosteronism

artículo científico publicado en 2020

Aspergillus fumigatus cell wall components differentially modulate host TLR2 and TLR4 responses

artículo científico publicado en 2010

Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3.

artículo científico publicado en 2013

Assessment of inflammasome activation in primary human immune cells.

artículo científico publicado en 2013

Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout

artículo científico publicado en 2023

Association of NF-κB polymorphisms with clinical outcome of non-medullary thyroid carcinoma

artículo científico publicado en 2017

Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis

scholarly article by Leo A B Joosten et al published 1 February 2003 in Arthritis and Rheumatism

Asymptomatic hyperuricaemia: a silent activator of the innate immune system

scientific article published on 10 December 2019

Author Correction: A guiding map for inflammation

scientific article published on 07 December 2020

Author Correction: Engineering cytokine therapeutics

scientific article published in 2023

Author Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

scientific article published in 2021

Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes

scientific article published in 2021

Author Correction: Training the trainable cells of the immune system and beyond

artículo científico publicado en 2020

Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations

scientific article published in 2023

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

artículo científico publicado en 2014

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β)

artículo científico publicado en 2013

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

artículo científico publicado en 2011

Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi

artículo científico publicado en 2016

B. burgdorferisensu lato-induced inhibition of antigen presentation is mediated by RIP1 signaling resulting in impaired functional T cell responses towards Candida albicans

artículo científico publicado en 2020

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

artículo científico publicado en 2020

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

artículo científico publicado en 2018

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

artículo científico publicado en 2020

BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

artículo científico publicado en 2020

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection

artículo científico publicado en 2014

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

artículo científico publicado en 2012

Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.

artículo científico publicado en 2018

Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications

artículo científico publicado en 2016

Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4

artículo científico publicado en 2007

Beyond adaptive immunity: induction of trained immunity by COVID-19 adenoviral vaccines

scientific article published in 2023

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

artículo científico

Blueprints of signaling interactions between pattern recognition receptors: implications for the design of vaccine adjuvants.

artículo científico publicado en 2013

Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12

scientific article published in 2022

Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense

scientific article published on 03 February 2020

Borrelia burgdorferi inhibits NADPH-mediated reactive oxygen species production through the mTOR pathway

artículo científico publicado en 2022

Borrelia burgdorferi is strong inducer of IFN-γ production by human primary NK cells

scientific article published in 2022

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

artículo científico publicado en 2010

Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.

artículo científico publicado en 2015

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

artículo científico publicado en 2016

Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans

artículo científico publicado en 2009

CHIP and gout: trained immunity?

scientific article published in 2022

CHONDROCYTE NONRESPONSIVENESS TO INSULIN‐LIKE GROWTH FACTOR 1 IN EXPERIMENTAL ARTHRITIS

scientific article published in 1989

CRELD1 modulates homeostasis of the immune system in mice and humans

scientific article published on 09 November 2020

CXCL9, a promising biomarker in the diagnosis of chronic Q fever

artículo científico publicado en 2017

Candida albicans dampens host defense by downregulating IL-17 production.

artículo científico publicado en 2010

Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes.

artículo científico publicado en 2012

Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway

artículo científico publicado en 2013

Candida albicans releases soluble factors that potentiate cytokine production by human cells through a protease-activated receptor 1- and 2-independent pathway

artículo científico publicado en 2009

Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion

artículo científico publicado en 2012

Caspase-1, but not ASC or NLRP3 inflammasome components, mediates IL-1beta activation and antifungal defense in disseminated candidiasis

scientific article published in 2009

Caspase-12 and the inflammatory response to Yersinia pestis

artículo científico publicado en 2009

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

artículo científico publicado en 2019

Cell-Death Dependent Interleukin-1α Release Activates Host NLRP3 Inflammasome and Promotes Epithelial-Mesenchymal Transition in Metastatic Breast Cancer

artículo científico publicado en 2022

Cellular metabolism of myeloid cells in sepsis

artículo científico publicado en 2016

Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.

artículo científico publicado en 2018

Characterization of gut microbial structural variations as determinants of human bile acid metabolism

scientific article published in 2021

Chocolate consumption modulates cytokine production in healthy individuals

artículo científico publicado en 2013

Cholesterol accumulation caused by low density lipoprotein receptor deficiency or a cholesterol-rich diet results in ectopic bone formation during experimental osteoarthritis

artículo científico publicado en 2013

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

artículo científico publicado en 2021

Circulating interleukin-38 concentrations in healthy adults

scientific article published in 2022

Circulating lipoproteins are a crucial component of host defense against invasive Salmonella typhimurium infection

artículo científico publicado en 2009

Citrullination of synovial proteins in murine models of rheumatoid arthritis

artículo científico publicado en 2003

Combination of biomarkers for the discrimination between bacterial and viral lower respiratory tract infections

artículo científico publicado en 2012

Combined B- and T-cell deficiency does not protect against obesity-induced glucose intolerance and inflammation

artículo científico publicado en 2013

Complement activation in the disease course of COVID-19 and its effects on clinical outcomes

artículo científico publicado en 2020

Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs

artículo científico publicado en 2012

Complex immunometabolic pathways mediate the interaction between thyroid carcinoma cells and tumor-associated macrophages

artículo científico publicado en 2016

Comprehensive phenotyping of circulating immune cell subsets in people living with HIV

scientific article published in 2022

Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis

artículo científico publicado en 2009

Conceptualization of population-specific human functional immune-genomics projects to identify factors that contribute to variability in immune and infectious diseases

scientific article published in 2021

Concerns about the external validity of the study ‘prevalence of persistent symptoms after treatment for Lyme borreliosis: A prospective observational cohort study’-authors´ reply

scientific article published in 2022

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

artículo científico publicado en 2014

Correction for Bekkering et al., "In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes".

artículo científico publicado en 2017

Correction to “Prevalence of persistent symptoms after treatment for lyme borreliosis: a prospective observational cohort study”

scientific article published in 2023

Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

artículo científico publicado en 2020

Corrigendum: Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice

scholarly article published in Frontiers in Immunology

Coxiella burnetii isolates originating from infected cattle induce a more pronounced proinflammatory cytokine response compared to isolates from infected goats and sheep

artículo científico publicado en 2017

Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli

artículo científico publicado en 2007

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

artículo científico publicado en 2011

Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species

artículo científico publicado en 2013

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study

artículo científico publicado en 2011

Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial

artículo científico publicado en 2015

Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation

artículo científico publicado en 2014

Cytokine production from stimulated whole blood cultures in rheumatoid arthritis patients treated with various TNF blocking agents

artículo científico publicado en 2009

Cytokine profiles in patients with Q fever fatigue syndrome

artículo científico publicado en 2019

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment

artículo científico publicado en 2017

Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species

artículo científico publicado en 2017

DEL-1 promotes macrophage efferocytosis and clearance of inflammation

artículo científico publicado en 2018

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial

artículo científico publicado en 2020

Deadly COVID-19 among the elderly: Innate immune memory helping those most in need

artículo científico publicado en 2021

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

artículo científico publicado en 2020

Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models ⬇️

artículo científico publicado el 1 de octubre de 2003

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

artículo científico publicado en 2006

Defining trained immunity and its role in health and disease

scientific article published on 04 March 2020

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

artículo científico publicado en 2011

Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice

artículo científico publicado en 2011

Detection of Novel Biomarkers in Pediatric Autoimmune Hepatitis by Proteomic Profiling

artículo científico publicado en 2023

Development of interleukin-1 receptor antagonist mutants with enhanced antagonistic activity in vitro and improved therapeutic efficacy in collagen-induced arthritis

artículo científico publicado en 2008

Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non‐genetic factors

scientific article published in 2022

Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits

artículo científico publicado en 2016

Differential Toll-like receptor recognition and induction of cytokine profile by Bifidobacterium breve and Lactobacillus strains of probiotics.

artículo científico publicado en 2011

Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial

artículo científico publicado en 2020

Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure

artículo científico publicado en 2010

Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses

artículo científico publicado en 2015

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

artículo científico publicado en 2008

Differential in vitro cytokine induction by the species of Cryptococcus gattii complex

artículo científico publicado en 2018

Differential recognition and cytokine induction by the peptidorhamnomannan from Sporothrix brasiliensis and S. Schenckii

scientific article published in 2022

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

artículo científico publicado en 2008

Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice

artículo científico publicado en 2014

Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I.

artículo científico publicado en 2010

Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19

scientific article published in 2021

Early cytokine and antibody responses against Coxiella burnetii in aerosol infection of BALB/c mice

artículo científico

Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome.

artículo científico publicado en 2018

Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study

scientific article published in 2023

Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males

scientific article published in Scientific Reports

Effects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 mice

artículo científico publicado en 2013

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

artículo científico publicado en 2010

Engineering cytokine therapeutics

scientific article published in 2023

Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals

artículo científico publicado en 2012

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.

artículo científico publicado en 2014

Epigenetics and trained immunity.

artículo científico publicado en 2017

Erratum: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance

artículo científico publicado en 2015

Erratum: Corrigendum: Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

article

Erratum: IL-1 family nomenclature

scholarly article by Charles A. Dinarello et al published March 2011 in Nature Immunology

Evolution of cytokine production capacity in ancient and modern European populations

scientific article published in 2021

Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans

artículo científico publicado en 2022

Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection

artículo científico publicado en 2010

Ex-vivo inhibited cytokine profiling explains inferior treatment response to golimumab after adalimumab failure in rheumatoid arthritis

artículo científico publicado en 2017

Excessive interleukin-1 signaling determines the development of Th1 and Th17 responses in chronic inflammation

artículo científico publicado en 2010

Exploring the Role of IL-32 in HIV-Related Kaposi Sarcoma.

artículo científico publicado en 2017

Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis

artículo científico publicado en 2012

Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma

artículo científico publicado en 2004

Factors modulating the inflammatory response in acute gouty arthritis

artículo científico publicado en 2016

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

artículo científico publicado en 2016

Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock

scholarly article

Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism

article published in 2005

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

artículo científico publicado en 2013

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

artículo científico publicado en 2014

Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

scientific article published in 2021

Genetic Variation in Pattern Recognition Receptors and Adaptor Proteins Associated With Development of Chronic Q Fever

artículo científico publicado en 2015

Genetic Variation in TLR10, an Inhibitory Toll-Like Receptor, Influences Susceptibility to Complicated Skin and Skin Structure Infections

artículo científico publicado en 2015

Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content

artículo científico publicado en 2020

Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease

artículo científico publicado en 2009

Genetic basis for recurrent vulvo-vaginal candidiasis

artículo científico

Genetic determinants of fungi-induced ROS production are associated with the risk of invasive pulmonary aspergillosis

artículo científico publicado en 2022

Genetic diversity of lactase persistence in East African populations.

artículo científico publicado en 2016

Genetic regulators of cytokine responses upon BCG vaccination in children from West Africa

scientific article published in 2023

Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients

artículo científico publicado en 2018

Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro.

artículo científico publicado en 2015

Genetic variation in pattern recognition receptors: functional consequences and susceptibility to infectious disease.

artículo científico

Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia

artículo científico publicado en 2011

Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis

artículo científico publicado en 2020

Genome-Wide Association Study Reveals CLEC7A and PROM1 as Potential Regulators of Paracoccidioides brasiliensis-Induction of Cytokine Production in Peripheral Blood Mononuclear Cells

scientific article published in 2023

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

artículo científico publicado en 2016

Gout

artículo científico publicado en 2019

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout

scientific article published on 9 September 2019

Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: a comparative study in gene-deficient mice

article

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk

scientific article published on 11 April 2019

Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity

artículo científico publicado en 2020

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

artículo científico publicado en 2021

High LDL-C levels attenuate onset of inflammation and cartilage destruction in antigen-induced arthritis

scientific article published on 07 May 2019

High efficacy of Toll-like receptor 4 targeting in murine and humanized models of rheumatoid arthritis in comparison with IL-1 and TNF inhibitors (THER6P.860)

scientific article published in 2014

High variability of TLR4 gene in different ethnic groups in Iran

artículo científico publicado en 2011

High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells.

artículo científico publicado en 2018

High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study

artículo científico publicado en 2012

High-throughput proteomic analysis reveals systemic dysregulation in virally suppressed people living with HIV

scientific article published in 2023

Host and Environmental Factors Influencing Individual Human Cytokine Responses

artículo científico publicado en 2016

How the COVID-19 pandemic highlights the necessity of animal research

scientific article published on 10 August 2020

How the COVID-19 pandemic highlights the necessity of animal research

artículo científico publicado en 2020

Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis

artículo científico publicado en 2015

Human Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.

artículo científico publicado en 2018

Human TLR10 is an anti-inflammatory pattern-recognition receptor

artículo científico publicado en 2014

Human dectin-1 deficiency and mucocutaneous fungal infections

artículo científico publicado en 2009

Human genetic susceptibility to Candida infections.

artículo científico

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

artículo científico publicado en 2020

Human variation in population-wide gene expression data predicts gene perturbation phenotype

artículo científico publicado en 2022

Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons

artículo científico publicado en 2020

Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1β Transcription in Human Adipose Tissue ⬇️

artículo científico publicado el 1 de febrero de 2011

Hypothesis: stimulation of trained immunity as adjunctive immunotherapy in cancer

artículo científico publicado en 2017

IL-1 Family Cytokine Pathways Underlying NAFLD: Towards New Treatment Strategies.

artículo científico publicado en 2018

IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation.

artículo científico publicado en 1999

IL-1 family cytokines as drivers and inhibitors of trained immunity

artículo científico publicado en 2022

IL-1 family nomenclature

artículo científico publicado en 2010

IL-1 in chronic arthritis, lessons from animal models

scientific article published in 2006

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

scientific article published on 18 February 2014

IL-1-8 IL-1β and the development of Th17 responses

artículo científico publicado en 2010

IL-15 enhances the capacity of primary human macrophages to control Leishmania braziliensis infection by IL-32/vitamin D dependent and independent pathways

artículo científico publicado en 2020

IL-17 produced by Paneth cells drives TNF-induced shock

artículo científico publicado en 2008

IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance

artículo científico publicado en 2003

IL-18 serum concentration is markedly elevated in acute EBV infection and can serve as a marker for disease severity.

artículo científico publicado en 2012

IL-1beta processing in host defense: beyond the inflammasomes

artículo científico publicado en 2010

IL-32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1/Th17 cytokines

scientific article published on 4 August 2019

IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis

scientific article published on 30 January 2017

IL-32 promotes angiogenesis

artículo científico publicado en 2013

IL-32, a proinflammatory cytokine in rheumatoid arthritis ⬇️

artículo científico publicado en 2006

IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2

IL-32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis.

artículo científico publicado en 2017

IL-37 protects against obesity-induced inflammation and insulin resistance.

artículo científico publicado en 2014

IL-38 Gene Deletion Worsens Murine Colitis

scientific article published in 2022

IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist

artículo científico publicado en 2012

IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation

artículo científico publicado en 2014

IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling

artículo científico publicado en 2021

INHIBITION OF CHRONIC DESTRUCTIVE ARTHRITIS USING A NATURALLY OCCURRING TLR4 ANTAGONIST

scientific article published in 2006

INTERACTING NON-SPECIFIC IMMUNOLOGICAL EFFECTS OF BCG AND Tdapf VACCINATIONS: AN EXPLORATIVE RANDOMIZED TRIAL

artículo científico publicado en 2020

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.

artículo científico publicado en 2018

Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis

artículo científico publicado en 2006

Identifying platelet-derived factors as amplifiers of <i>B. burgdorferi</i>-induced cytokine production

scientific article published in 2022

Immune activation by medium-chain triglyceride-containing lipid emulsions is not modulated by n-3 lipids or toll-like receptor 4.

artículo científico publicado en 2015

Immune defence against Candida fungal infections

artículo científico

Immune modulatory effects of progesterone on oxLDL‐induced trained immunity in monocytes

artículo científico publicado en 2022

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.

artículo científico publicado en 2014

Immunogenicity of the Q fever skin test

artículo científico publicado en 2014

Immunometabolic Pathways in BCG-Induced Trained Immunity

artículo científico publicado en 2016

Immunometabolic circuits in trained immunity

artículo científico publicado en 2016

Immunometabolism orchestrates training of innate immunity in atherosclerosis

artículo científico publicado en 2019

Immunotherapeutic Potential of Interleukin-32 and Trained Immunity for Leishmaniasis Treatment

artículo científico publicado en 2020

Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses

artículo científico publicado en 2021

In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes

artículo científico publicado en 2016

Increase in expression of receptor activator of nuclear factor kappaB at sites of bone erosion correlates with progression of inflammation in evolving collagen-induced arthritis

artículo científico publicado en 2002

Increased Plasma Heparanase Activity in COVID-19 Patients

artículo científico publicado en 2020

Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

artículo científico publicado en 2011

Increased innate immune responses by interleukin-22 contributes to the inflammatory process in rheumatoid arthritis

article

Increased plasma heparanase activity in COVID-19 patients

artículo científico publicado en 2020

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

artículo científico publicado en 2019

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G

artículo científico publicado en 2018

Induction of cartilage damage by overexpression of T cell interleukin-17A in experimental arthritis in mice deficient in interleukin-1.

artículo científico publicado en 2005

Inflammasome activation and IL-1β and IL-18 processing during infection

artículo científico publicado en 2011

Inflammasome inhibition: putting out the fire

artículo científico publicado en 2015

Inflammasome is a central player in the induction of obesity and insulin resistance

artículo científico publicado en 2011

Inflammasome-independent modulation of cytokine response by autophagy in human cells

artículo científico publicado en 2011

Inflammasome-independent regulation of IL-1-family cytokines

artículo científico

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

artículo científico publicado en 2010

Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis

artículo científico publicado en 2016

Inflammation links excess fat to insulin resistance: the role of the interleukin-1 family

artículo científico

Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis

artículo científico publicado en 2011

Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability

scientific article published on 26 August 2021

Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF

artículo científico publicado en 2009

Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

artículo científico publicado en 2009

Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis

artículo científico publicado en 2005

Inhibition of HDAC Activity by ITF2357 Ameliorates Joint Inflammation and Prevents Cartilage and Bone Destruction in Experimental Arthritis ⬇️

artículo científico publicado el 11 de febrero de 2011

Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

artículo científico publicado en 2007

Inhibition of caspase-1 activation in Gram-negative sepsis and experimental endotoxemia

artículo científico publicado en 2011

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens

artículo científico publicado en 2019

Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo

artículo científico publicado en 2016

Innate immune cells in the pathophysiology of calcific aortic valve disease: lessons to be learned from atherosclerotic cardiovascular disease?

scientific article published in 2022

Innate immune memory: Implications for host responses to damage-associated molecular patterns

artículo científico publicado en 2016

Innate immune recognition of Mycobacterium tuberculosis

artículo científico publicado en 2011

Innate immunity networks during infection with Borrelia burgdorferi

artículo científico publicado en 2014

Insights into the role of IL-32 in cancer

scientific article published on 08 May 2018

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

artículo científico publicado en 2015

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

artículo científico publicado en 2021

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

artículo científico publicado en 2018

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

artículo científico publicado en 2016

Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

artículo científico publicado en 2018

Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.

artículo científico publicado en 2011

Interleukin 32: a novel player in the control of infectious diseases.

artículo científico publicado en 2016

Interleukin 32γ (IL-32γ) is highly expressed in cutaneous and mucosal lesions of American Tegumentary Leishmaniasis patients: association with tumor necrosis factor (TNF) and IL-10.

artículo científico publicado en 2014

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

artículo científico publicado en 2017

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice

artículo científico publicado en 2008

Interleukin-1 receptor-associated kinase 4 links innate immunity to the pathogenesis of rheumatoid arthritis

artículo científico publicado en 2009

Interleukin-17 acts independently of TNF-alpha under arthritic conditions

scientific article published on 01 May 2006

Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.

artículo científico publicado en 2005

Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction

artículo científico publicado en 2004

Interleukin-1β activation during acute joint inflammation: a limited role for the NLRP3 inflammasome in vivo

scientific article published on 22 December 2010

Interleukin-1β in innate inflammation, autophagy and immunity

artículo científico publicado en 2013

Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases

artículo científico publicado en 2017

Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

artículo científico publicado en 2008

Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes.

artículo científico publicado en 2018

Interleukin-32: An endogenous danger signal or master regulator of intracellular pathogen infections-Focus on leishmaniases.

artículo científico publicado en 2018

Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death

artículo científico publicado en 2012

Interleukin-32γ in the Control of Acute Experimental Chagas Disease

scientific article published in 2022

Interleukin-38 in Health and Disease

scientific article published in 2022

Interplay between Candida albicans and the mammalian innate host defense.

artículo científico

Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration

scientific article published on 14 June 2019

Intracellular Alarmins: Hidden dangers signals crucial for cancer, host defense and inflammatory processes

artículo científico publicado en 2018

Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections

artículo científico publicado en 2023

In vitro induction of trained immunity in adherent human monocytes

scientific article published in 2021

Kallikrein augments the anticoagulant function of the protein C system in thrombin generation

scientific article published in 2022

Leishmania (Viannia) braziliensis amastigotes induces the expression of TNFα and IL-10 by human peripheral blood mononuclear cells in vitro in a TLR4-dependent manner.

artículo científico publicado en 2016

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

scientific article published on 25 October 2019

Limited humoral and cellular responses to Q fever vaccination in older adults with risk factors for chronic Q fever

artículo científico publicado en 2013

Limited impact of impaired awareness of hypoglycaemia and severe hypoglycaemia on the inflammatory profile of people with type 1 diabetes

scientific article published in 2020

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity ⬇️

artículo científico publicado en 2016

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

artículo científico publicado en 2016

Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation

artículo científico publicado en 2009

Local interleukin-12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis.

artículo científico publicado en 2002

Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity

artículo científico publicado en 2013

Long-term in vitro and in vivo effects of γ-irradiated BCG on innate and adaptive immunity

artículo científico publicado en 2015

Low induction of proinflammatory cytokines parallels evolutionary success of modern strains within the Mycobacterium tuberculosis Beijing genotype

artículo científico publicado en 2013

Low interleukin-17A production in response to fungal pathogens in patients with chronic granulomatous disease

artículo científico publicado en 2011

Lyme Borreliosis Serology: A Prospective Cohort Study of Forestry Service Workers in the Netherlands over 8 Years (2008 to 2016) of Follow-Up

scientific article published in 2023

MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice

artículo científico publicado en 2014

MST1R mutation as a genetic cause of Lady Windermere syndrome

artículo científico publicado en 2017

Master and commander: epigenetic regulation of macrophages

artículo científico

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

artículo científico publicado en 2018

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD

scientific article published on 30 January 2020

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

artículo científico publicado en 2016

Mimicking Behcet's disease: GM-CSF gain of function mutation in a family suffering from a Behcet's disease-like disorder marked by extreme pathergy

artículo científico publicado en 2020

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

artículo científico publicado en 2018

Modulation of Toll-like receptor 2 (TLR2) and TLR4 responses by Aspergillus fumigatus

scientific article published on 09 February 2009

Modulation of Toll-like receptor ligands and Candida albicans-induced cytokine responses by specific probiotics.

artículo científico publicado en 2012

Modulation of inflammation by autophagy: consequences for Crohn's disease.

artículo científico

Monocyte and macrophage immunometabolism in atherosclerosis.

artículo científico publicado en 2017

Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19

artículo científico publicado en 2022

Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome

scientific article published on 26 November 2020

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

artículo científico publicado en 2012

Murine antigen-induced arthritis

artículo científico publicado en 2007

Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1.

artículo científico publicado en 2010

Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism

artículo científico publicado en 2006

Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production

scientific article published in 2023

NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis

scientific article published on 03 August 2018

NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with Crohn's disease

artículo científico publicado en 2008

Neisseria meningitidislipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production ⬇️

artículo científico publicado el 18 de noviembre de 2010

Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis

scientific article published in 2021

Neutrophil-mediated inhibition of proinflammatory cytokine responses

artículo científico publicado en 2012

New gout test: enhanced ex vivo cytokine production from PBMCS in common gout patients and a gout patient with Kearns-Sayre syndrome

artículo científico publicado en 2014

No Signs of Neuroinflammation in Women With Chronic Fatigue Syndrome or Q Fever Fatigue Syndrome Using the TSPO Ligand [<sup>11</sup>C]-PK11195

scientific article published in 2021

Non-specific effects of vaccines: Current evidence and potential implications

artículo científico publicado en 2018

Novel cardiovascular biomarkers in women with a history of early preeclampsia

artículo científico publicado en 2014

Novel insights into the biology of interleukin-32.

artículo científico

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

artículo científico publicado en 2018

OR04-2 Aldosterone Induces Trained Immunity via Fatty Acid Synthesis.

artículo científico publicado en 2019

Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides

artículo científico publicado en 2019

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

artículo científico publicado en 2021

Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity

scientific article published in 2023

Oxidative and nitrosative stress in acute pancreatitis. Modulation by pentoxifylline and oxypurinol

artículo científico publicado en 2011

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans ⬇️

artículo científico

Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes

artículo científico publicado en 2014

Oxidized phospholipids on lipoprotein(a) induce epigenetic reprogramming and an increased pro-atherogenic response in human monocytes

scientific article published in 2017

PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis

artículo científico publicado en 2009

PS1 - 1. TLR-3 is highly expressed in human adipocytes, but deficiency of TLR3 does not protect against obesity-induced inflammation and insulin resistance in mice

scientific article published in 2013

PS2 - 9. Effect of B- and T-cell deficiency on obesity-induced inflammation and insulin resistance

scientific article published in 2011

PS2-102. Cross-tolerance and priming between C-type lectin receptors and TLRs

scientific article published in 2011

PS2-26 Crohn’s disease associated ATG16L1 polymorphism modulates cytokine production after NOD2 engagement

scientific article published in 2010

PS21 - 102. IL-37 protects against obesity-induced inflammation and insulin resistance in mice

artículo científico publicado en 2012

PS4 - 4. Proteinase 3: a new link between inflammation, obesity and Type 2 Diabetes

scientific article published in 2013

Paracoccidioides brasiliensis induces IL-32 and is controlled by IL-15/IL-32/vitamin D pathway in vitro

scientific article published in 2021

People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells

artículo científico publicado en 2022

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

scientific article published on 08 May 2020

Physiological and Genetic Adaptations to Diving in Sea Nomads

artículo científico publicado en 2018

Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination

artículo científico publicado en 2022

Plasma proteins as a predictor of chronological age in people living with HIV: a cross-sectional study

scientific article published in 2022

Platelet Integrin αIIbβ3 Activation is Associated with 25-Hydroxyvitamin D Concentrations in Healthy Adults

scientific article published on 05 May 2020

Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout

scientific article published on 12 March 2020

Polymorphisms in autophagy genes and susceptibility to tuberculosis

artículo científico publicado en 2012

Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate

artículo científico publicado en 2010

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

scientific article published on 22 July 2019

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis

artículo científico publicado en 2019

Predictive value of serum calprotectin (S100A8/A9) for clinical response after starting or tapering anti-TNF treatment in patients with rheumatoid arthritis.

artículo científico publicado en 2018

Presence of Genetic Variants Among Young Men With Severe COVID-19

scientific article published on 24 July 2020

Prevalence and associated risk factors for Kaposi's sarcoma among HIV-positive patients in a referral hospital in Northern Tanzania: a retrospective hospital-based study

article

Prevalence and determinants of persistent symptoms after treatment for Lyme borreliosis: study protocol for an observational, prospective cohort study (LymeProspect)

artículo científico publicado en 2019

Prevalence of persistent symptoms after treatment for lyme borreliosis: A prospective observational cohort study

scientific article published in 2021

Pro-inflammatory Monocyte Phenotype During Acute Progression of Cerebral Small Vessel Disease

scientific article published in 2021

Profiling Serum Antibodies Against Muscle Antigens in Facioscapulohumeral Muscular Dystrophy Finds No Disease-Specific Autoantibodies

scientific article published in 2021

Prosaposin mediates inflammation in atherosclerosis

scientific article published in 2021

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.

artículo científico publicado en 2014

Protective immune response mediated by neutrophils in experimental visceral leishmaniasis is enhanced by IL-32γ

scientific article published in 2022

Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis

artículo científico publicado en 2013

Publisher Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

scientific article published in 2021

R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway

artículo científico publicado en 2010

Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

artículo científico publicado en 2020

Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease

artículo científico publicado en 2010

Receptor recognition of and immune intracellular pathways for Veillonella parvula lipopolysaccharide

artículo científico publicado en 2009

Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction

artículo científico publicado en 2010

Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors

artículo científico publicado en 2014

Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects

artículo científico publicado en 2020

Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly.

artículo científico publicado en 2016

Relation Between Plasma Proteomics Analysis and Major Adverse Cardiovascular Events in Patients With Stable Coronary Artery Disease

scientific article published in 2022

Reply to: ‘Lack of evidence for intergenerational inheritance of immune resistance to infections’

scientific article published in 2022

Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease

artículo científico publicado en 2020

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells

scientific article published in 2023

Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study.

artículo científico publicado en 2012

Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells

scientific article published on 14 September 2016

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis

artículo científico publicado en 2017

Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

artículo científico publicado en 2020

Role of Dectin-2 for host defense against systemic infection with Candida glabrata.

artículo científico publicado en 2013

Role of Glutamine Metabolism in Host Defense Against Mycobacterium tuberculosis Infection

artículo científico publicado en 2019

Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis

artículo científico publicado en 2013

Role of autophagy genetic variants for the risk of Candida infections.

artículo científico publicado en 2014

Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome

artículo científico publicado en 2014

Role of glutathione metabolism in host defense against Borrelia burgdorferi infection.

artículo científico publicado en 2018

Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease

artículo científico publicado en 2011

STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis

artículo científico publicado en 2011

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

artículo científico publicado en 2011

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

artículo científico publicado en 2020

Seasonal and Nonseasonal Longitudinal Variation of Immune Function

scientific article published in 2021

Severe Candida spp. infections: new insights into natural immunity

artículo científico publicado en 2010

Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity

artículo científico publicado en 2020

Sex-specific Association Between Adipose Tissue Inflammation and Vascular and Metabolic Complications of Obesity

scientific article published in 2023

Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production

artículo científico publicado en 2008

Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes

artículo científico publicado en 2021

Sixteen-Week Physical Activity Intervention in Subjects With Increased Cardiometabolic Risk Shifts Innate Immune Function Towards a Less Proinflammatory State

scientific article published on 18 October 2019

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

artículo científico publicado en 2015

Specific and Complex Reprogramming of Cellular Metabolism in Myeloid Cells during Innate Immune Responses

artículo científico publicado en 2017

Specific interferon γ detection for the diagnosis of previous Q fever

artículo científico publicado en 2013

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

artículo científico publicado en 2008

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

artículo científico publicado en 2015

Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study

scientific article published in 2022

Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus

scientific article published on 30 January 2020

Systemic administration of β-glucan induces immune training in microglia

scientific article published in 2021

T cell dependence of chronic destructive murine arthritis induced by repeated local activation of toll-like receptor–driven pathways: Crucial role of both interleukin-1β and interleukin-17

artículo científico publicado en 2008

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4ig but is successfully treated by interleukin-17 neutralization

article

TLR-3 is present in human adipocytes, but its signalling is not required for obesity-induced inflammation in adipose tissue in vivo

artículo científico publicado en 2015

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

artículo científico publicado en 2014

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes

artículo científico publicado en 2011

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

artículo científico

TLRs of Our Fathers

artículo científico publicado en 2016

TNF-induced structural joint damage is mediated by IL-1.

artículo científico publicado en 2007

TREM-1 interaction with the LPS/TLR4 receptor complex

artículo científico publicado el 1 de marzo de 2011

TREM-1: intracellular signaling pathways and interaction with pattern recognition receptors

artículo científico

Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size

scientific article published in 2023

Targeted plasma proteomics reveals upregulation of distinct inflammatory pathways in people living with HIV

scientific article published in 2022

Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19

scientific article published in 2022

Targeting inflammasomes in rheumatic diseases

artículo científico publicado en 2013

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

scientific article published in 2021

Tendon degeneration is not mediated by regulation of Toll-like receptors 2 and 4 in human tenocytes

scientific article published on 01 August 2009

Th17 responses and host defense against microorganisms: an overview

scientific article published on December 2009

The 2000HIV study: Design, multi-omics methods and participant characteristics

artículo científico publicado en 2022

The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation

scientific article published in 2021

The Association of TSH and Thyroid Hormones With Lymphopenia in Bacterial Sepsis and COVID-19

scientific article published in 2021

The BNT162b2 mRNA Vaccine Against SARS-CoV-2 Reprograms Both Adaptive and Innate Immune Responses

scientific article published in 2021

The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2.

artículo científico publicado en 2010

The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease

artículo científico publicado en 2022

The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses

artículo científico publicado en 2022

The Gut Microbiome Composition Is Altered in Long-standing Type 1 Diabetes and Associates With Glycemic Control and Disease-Related Complications

scientific article published in 2022

The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses

artículo científico publicado en 2013

The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men

scientific article published in 2021

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans

scientific article published on 19 November 2018

The Intersection of Epigenetics and Metabolism in Trained Immunity

artículo científico publicado en 2020

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity

artículo científico publicado en 2018

The Janus face of Bartonella quintana recognition by Toll-like receptors (TLRs): a review

artículo científico publicado en 2008

The NLRP1-IL18 Connection: A Stab in the Back of Obesity-Induced Inflammation

artículo científico publicado en 2016

The NOD2 receptor is crucial for immune responses towards New World Leishmania species

artículo científico publicado en 2017

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders

artículo científico publicado en 2018

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

artículo científico publicado en 2015

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis

artículo científico publicado en 2016

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by Beta-Glucan

scientific article published in 2019

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

artículo científico publicado en 2020

The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome

artículo científico publicado en 2004

The anti-CD20 antibody Rituximab reduces the Th17 response

The anti-CD20 antibody rituximab reduces the Th17 cell response

article

The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity

artículo científico publicado en 2021

The classical CD14⁺⁺ CD16⁻ monocytes, but not the patrolling CD14⁺ CD16⁺ monocytes, promote Th17 responses to Candida albicans

artículo científico publicado en 2011

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

artículo científico publicado en 2011

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases.

artículo científico publicado en 2014

The effect of host genetics on the gut microbiome

artículo científico

The effect of the ATG16L1 Thr300Ala polymorphism on susceptibility and outcome of patients with epithelial cell-derived thyroid carcinoma

artículo científico publicado en 2012

The effect of the interleukin-1 cytokine family members IL-1F6 and IL-1F8 on adipocyte differentiation

artículo científico publicado en 2010

The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production

artículo científico publicado en 2013

The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis

artículo científico publicado en 2015

The evolutionary history of TLR4 polymorphisms in Europe

artículo científico publicado en 2012

The functional variant (Asp299gly) of toll-like receptor 4 (TLR4) influences TLR4-mediated cytokine production in rheumatoid arthritis

scientific article published on 15 March 2008

The future clinical implications of trained immunity

scientific article published in 2022

The gut microbiome as mediator between diet and its impact on immune function

scientific article published in 2022

The impact of pre-existing thyroid diseases on susceptibility to respiratory infections or self-reported sickness during the SARS-CoV-2 pandemic

scientific article published in 2022

The impact of sex hormones on BCG-induced trained immunity

artículo científico publicado en 2018

The inflammasome and caspase-1 activation: a new mechanism underlying increased inflammatory activity in human visceral adipose tissue

artículo científico publicado en 2011

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.

scientific article published on 04 July 2011

The inflammasome puts obesity in the danger zone

artículo científico publicado en 2012

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

artículo científico publicado en 2010

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

scientific article published in 2009

The influence of the gut microbiome on BCG-induced trained immunity

artículo científico publicado en 2021

The interplay between central metabolism and innate immune responses

artículo científico publicado en 2014

The interplay between inflammasome activation and antifungal host defense

artículo científico

The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis

artículo científico publicado en 2018

The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis

artículo científico publicado en 2012

The macrophage mannose receptor induces IL-17 in response to Candida albicans.

artículo científico publicado en 2009

The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis

artículo científico publicado en 2018

The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40

scientific article published on 01 November 2008

The orchestra of Toll-like receptors and their potential role in frequently occurring rheumatic conditions

artículo científico publicado en 2008

The role of IL-32 in Bacillus Calmette-Guérin (BCG)-induced trained immunity in infections caused by different Leishmania spp.

scientific article published in 2021

The role of NLRs and TLRs in the activation of the inflammasome

artículo científico publicado en 2008

The role of Toll-like receptor 10 in modulation of trained immunity

artículo científico publicado en 2019

The role of host immune cells and Borrelia burgdorferi antigens in the etiology of Lyme disease

artículo científico publicado en 2017

The role of interleukin-1 family members in hyperuricemia and gout

artículo científico publicado en 2020

The role of sirtuin 1 on the induction of trained immunity

scientific article published in 2021

The role of the interleukin-1 family in trained immunity

artículo científico publicado en 2018

Therapeutic targeting of trained immunity

artículo científico publicado en 2019

Thyrotrophin and thyroxine support immune homeostasis in humans

artículo científico publicado en 2021

Tissue metabolic changes drive cytokine responses to Mycobacterium tuberculosis.

artículo científico publicado en 2018

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

artículo científico publicado en 2012

Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88

artículo científico publicado en 2003

Toll-like receptors and chronic inflammation in rheumatic diseases: new developments

artículo científico publicado en 2016

Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics

artículo científico publicado en 2017

Toll‐like receptor 10 controls TLR2‐induced cytokine production in monocytes from patients with Parkinson's disease

scientific article published in 2021

Towards a role of interleukin-32 in atherosclerosis

artículo científico publicado en 2013

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease

artículo científico publicado en 2018

Trained Immunity and Local Innate Immune Memory in the Lung

artículo científico publicado en 2018

Trained Immunity as a Preventive Measure for Surgical Site Infections

artículo científico publicado en 2021

Trained Immunity in Primary Sjögren’s Syndrome: Linking Type I Interferons to a Pro-Atherogenic Phenotype

artículo científico publicado en 2022

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

scientific article published on 01 October 2020

Trained Immunity: Long-Term Adaptation in Innate Immune Responses

scientific article published on 22 October 2020

Trained Immunity: Reprogramming Innate Immunity in Health and Disease

artículo científico publicado en 2021

Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

artículo científico publicado en 2018

Trained immunity and inflammation in rheumatic diseases

artículo científico publicado en 2022

Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer

scientific article published on 16 July 2020

Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors.

artículo científico publicado en 2014

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

artículo científico publicado en 2020

Trained immunity: A program of innate immune memory in health and disease.

artículo científico publicado en 2016

Trained immunity: A smart way to enhance innate immune defence

artículo científico publicado en 2015

Trained immunity: adaptation within innate immune mechanisms

scientific article published in 2023

Trained innate immunity and atherosclerosis

artículo científico

Trained innate immunity as a mechanistic link between sepsis and atherosclerosis

artículo científico publicado en 2014

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

artículo científico publicado en 2021

Training the trainable cells of the immune system and beyond

artículo científico publicado en 2020

Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.

artículo científico publicado en 2009

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages.

artículo científico publicado en 2016

Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes

scientific article published on 06 August 2019

Transmission of trained immunity and heterologous resistance to infections across generations

artículo científico publicado en 2021

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation

artículo científico publicado en 2016

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation

artículo científico publicado en 2017

Treatment with Anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study

artículo científico publicado en 2011

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia

scientific article published on 13 June 2019

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

artículo científico publicado en 2004

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression

scientific article published in 2021

Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis

scholarly article by Marije I. Koenders et al published August 2011 in Arthritis and Rheumatism

Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade ⬇️

artículo científico publicado el 27 de diciembre de 2010

Understanding human immune function using the resources from the Human Functional Genomics Project

artículo científico publicado en 2016

Understanding the increased risk of infections in diabetes: innate and adaptive immune responses in type 1 diabetes

scientific article published in 2021

Untargeted Plasma Metabolomics and Gut Microbiome Profiling Provide Novel Insights into the Regulation of Platelet Reactivity in Healthy Individuals

scientific article published in 2021

Urate-induced epigenetic modifications in myeloid cells

scientific article published in 2021

Urate-induced immune programming: Consequences for gouty arthritis and hyperuricemia

artículo científico publicado en 2019

Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes

artículo científico publicado en 2021

Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway

artículo científico publicado en 2017

Variable recognition of Candida albicans strains by TLR4 and lectin recognition receptors.

artículo científico publicado en 2010

Variation in genes of β-glucan recognition pathway and susceptibility to opportunistic infections in HIV-positive patients

artículo científico publicado en 2011

Vasculometabolic and Inflammatory Effects of Aldosterone in Obesity

artículo científico publicado en 2020

Viable Coxiella burnetii Induces Differential Cytokine Responses in Chronic Q Fever Patients Compared to Heat-Killed Coxiella burnetii

article

Vitamin A induces inhibitory histone methylation modifications and down-regulates trained immunity in human monocytes

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

artículo científico publicado en 2018

mTOR Inhibition promotes TTF1-dependent redifferentiation and restores iodine uptake in thyroid carcinoma cell lines

artículo científico publicado en 2014

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

artículo científico publicado en 2014

oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming

scientific article published in 2021

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32

scientific article published on 01 September 2019

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de

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12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

A NOD for autophagy

A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis.

A functional genomics approach in Tanzanian population identifies distinct genetic regulators of cytokine production compared to European population

A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis

A guiding map for inflammation

A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis

A limited role of cytokine storm and fibrogenesis in COVID-19 related liver injury

A modular approach toward producing nanotherapeutics targeting the innate immune system

A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome

A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma

A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis

A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis.

A role for TLR10 in obesity and adipose tissue morphology.

A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity

A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection

ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation

Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

Absence of citrulline-specific autoantibodies in animal models of autoimmunity

Abstract 19220: Hepatic Steatosis is Independently Associated With an Increased Vascular Stiffness in Overweight Subjects

Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers

Activation of innate host defense mechanisms by Borrelia

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance

Acute Cytokine Response During Breast Cancer Surgery: Potential Role of Dexamethasone and Lidocaine and Relationship with Postoperative Pain and Complications - Analysis of Three Pooled Pilot Randomized Controlled Trials

Adaptation and memory in innate immunity

Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction

Advances in understanding molecular regulation of innate immune memory

Aldosterone induces trained immunity: the role of fatty acid synthesis

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

Altered Ex-Vivo Cytokine Responses in Children With Asymptomatic Plasmodium falciparum Infection in Burkina Faso: An Additional Argument to Treat Asymptomatic Malaria?

Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines

Amplifying elements of arthritis and joint destruction

An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism

An integrative genomics approach identifies KDM4 as a modulator of trained immunity

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

An integrative model of cardiometabolic traits identifies two types of metabolic syndrome

An observational study of innate immune responses in patients with acute appendicitis

Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance

Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity.

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra

Arterial Wall Inflammation and Increased Hematopoietic Activity in Patients With Primary Aldosteronism

Aspergillus fumigatus cell wall components differentially modulate host TLR2 and TLR4 responses

Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3.

Assessment of inflammasome activation in primary human immune cells.

Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout

Association of NF-κB polymorphisms with clinical outcome of non-medullary thyroid carcinoma

Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis

Asymptomatic hyperuricaemia: a silent activator of the innate immune system

Author Correction: A guiding map for inflammation

Author Correction: Engineering cytokine therapeutics

Author Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes

Author Correction: Training the trainable cells of the immune system and beyond

Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β)

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi

B. burgdorferisensu lato-induced inhibition of antigen presentation is mediated by RIP1 signaling resulting in impaired functional T cell responses towards Candida albicans

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

BCG-Induced Trained Immunity in Healthy Individuals: The Effect of Plasma Muramyl Dipeptide Concentrations

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.

Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications

Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4

Beyond adaptive immunity: induction of trained immunity by COVID-19 adenoviral vaccines

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

Blueprints of signaling interactions between pattern recognition receptors: implications for the design of vaccine adjuvants.