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193 A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.

artículo científico publicado en 2015

A protoplast system for studying tomato spotted wilt virus infection ⬇️

artículo científico publicado el 1 de julio de 1997

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

artículo científico publicado en 2022

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

artículo científico publicado en 2020

Antiviral Innate Immune Response Interferes with the Formation of Replication-Associated Membrane Structures Induced by a Positive-Strand RNA Virus

artículo científico publicado en 2016

Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling

artículo científico publicado en 2011

Arterivirus molecular biology and pathogenesis

artículo científico

CS17-5. Arteri- and nairovirus OTU domain-containing proteases target ubiquitin-regulated factors in the RLR-mediated innate immune signaling pathway

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

artículo científico publicado en 2021

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

artículo científico publicado en 2014

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

artículo científico publicado en 2013

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.

artículo científico publicado en 2017

Host Factors in Coronavirus Replication

artículo científico

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

artículo científico publicado en 2004

Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes

artículo científico publicado en 2009

Interaction of the innate immune system with positive-strand RNA virus replication organelles

artículo científico publicado en 2017

Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex

artículo científico publicado en 2012

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

artículo científico publicado en 2016

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

artículo científico publicado en 2007

Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates

artículo científico publicado en 2010

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

artículo científico publicado en 2005

Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

artículo científico publicado en 2012

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

artículo científico publicado en 2008

Structure and Function of Viral Deubiquitinating Enzymes.

artículo científico publicado en 2017

TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

artículo científico publicado en 2005

The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation

artículo científico publicado en 2009

The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease delays the innate immune response and enhances virulence in a mouse model

scientific article published on 30 August 2019

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway

artículo científico publicado en 2005

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

artículo científico publicado en 2010

Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.

artículo científico publicado en 2006

Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections

scientific article published on 18 October 2019

Viral OTU deubiquitinases: a structural and functional comparison

artículo científico publicado en 2014

Lista de obras de

193

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.

A protoplast system for studying tomato spotted wilt virus infection ⬇️

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Antiviral Innate Immune Response Interferes with the Formation of Replication-Associated Membrane Structures Induced by a Positive-Strand RNA Virus

Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling

Arterivirus molecular biology and pathogenesis

CS17-5. Arteri- and nairovirus OTU domain-containing proteases target ubiquitin-regulated factors in the RLR-mediated innate immune signaling pathway

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.

Host Factors in Coronavirus Replication

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes

Interaction of the innate immune system with positive-strand RNA virus replication organelles

Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

Structure and Function of Viral Deubiquitinating Enzymes.

TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation

The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease delays the innate immune response and enhances virulence in a mouse model

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.

Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections

Viral OTU deubiquitinases: a structural and functional comparison