Lista de obras -

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

scientific article (preprint)

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2015

A SARS-CoV-2 vaccine candidate would likely match all currently circulating strains

artículo científico publicado en 2020

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

scientific article published on 31 August 2020

A rational approach to heavy-atom derivative screening

artículo científico publicado en 2010

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

artículo científico publicado en 2004

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

artículo científico publicado en 2017

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

artículo científico publicado en 2015

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

artículo científico publicado en 2017

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

artículo científico publicado en 2014

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

article

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

artículo científico publicado en 2013

Computational prediction of N-linked glycosylation incorporating structural properties and patterns ⬇️

artículo científico publicado el 10 de julio de 2012

Conformational Mobility in the Active Site of a Heme Peroxidase

artículo científico publicado en 2006

Correction: Trinh, H.V., et al. Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort. Cells 2019, 8, 365

scientific article published on 06 June 2019

CprK crystal structures reveal mechanism for transcriptional control of halorespiration

artículo científico publicado en 2006

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site

artículo científico publicado en 2011

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells

artículo científico publicado en 2012

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

artículo científico publicado en 2019

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

artículo científico publicado en 2016

Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.

artículo científico publicado en 2013

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

artículo científico publicado en 2014

Evaluation of candidate vaccine approaches for MERS-CoV.

artículo científico publicado en 2015

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

artículo científico publicado en 2007

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

artículo científico publicado en 2004

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

scientific article published on 22 September 2010

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

artículo científico publicado en 2016

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

article

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

scientific article published on 30 January 2020

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

artículo científico publicado en 2015

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.

artículo científico publicado en 2019

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

scientific article published on 01 September 2020

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

artículo científico publicado en 2016

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

scientific article published on 09 April 2019

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape

artículo científico publicado en 2018

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

artículo científico publicado en 2016

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis

scientific article published on 12 September 2019

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

artículo científico publicado en 2021

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

artículo científico publicado en 2016

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

artículo científico publicado en 2014

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

artículo científico publicado en 2015

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

artículo científico publicado en 2008

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

artículo científico publicado en 2016

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

artículo científico publicado en 2019

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

artículo científico publicado en 2013

Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

artículo científico publicado en 2020

Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous andvirion-associated SERINC5

artículo científico publicado en 2020

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

artículo científico publicado en 2013

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

artículo científico publicado en 2020

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

artículo científico

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

artículo científico publicado en 2015

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

artículo científico publicado en 2019

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

artículo científico publicado en 2017

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

artículo científico publicado en 2015

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2017

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

artículo científico publicado en 2021

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

artículo científico publicado en 2015

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

artículo científico publicado en 2017

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

artículo científico publicado en 2016

Strategies to guide the antibody affinity maturation process

artículo científico publicado en 2015

Structural Determinants of Integrin Binding to the Talin Rod

artículo científico publicado en 2009

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

artículo científico publicado en 2021

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

artículo científico publicado en 2017

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)

article

Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain)

article

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2013

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

artículo científico publicado en 2017

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

artículo científico publicado en 2016

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

The Structural Basis of Ligand Recognition by Natural Killer Cell Receptors ⬇️

artículo científico publicado el 18 de mayo de 2011

The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors

artículo científico publicado en 2012

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

artículo científico publicado en 2016

Towards a rational approach for heavy-atom derivative screening in protein crystallography.

artículo científico publicado en 2008

Transient Protein Expression Facilitates X-ray Structural Studies of HIV-1.

artículo científico publicado en 2014

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

artículo científico publicado en 2014

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

artículo científico publicado en 2017

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

artículo científico publicado en 2016

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Lista de obras de

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

A SARS-CoV-2 vaccine candidate would likely match all currently circulating strains

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

A rational approach to heavy-atom derivative screening

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Computational prediction of N-linked glycosylation incorporating structural properties and patterns ⬇️

Conformational Mobility in the Active Site of a Heme Peroxidase

Correction: Trinh, H.V., et al. Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort. Cells 2019, 8, 365

CprK crystal structures reveal mechanism for transcriptional control of halorespiration

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

Evaluation of candidate vaccine approaches for MERS-CoV.

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort.

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous andvirion-associated SERINC5

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

Strategies to guide the antibody affinity maturation process

Structural Determinants of Integrin Binding to the Talin Rod

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)

Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain)

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus