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A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

artículo científico publicado en 2017

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

article

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

artículo científico publicado en 2015

Common genetic variants modulate pathogen-sensing responses in human dendritic cells

artículo científico publicado en 2014

Gene expression elucidates functional impact of polygenic risk for schizophrenia

artículo científico publicado en 2016

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of transcripts under balancing selection

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

artículo científico publicado en 2015

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

artículo científico publicado en 2014

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility

artículo científico publicado en 2018

Intersection of population variation and autoimmunity genetics in human T cell activation

artículo científico publicado en 2014

Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.

artículo científico publicado en 2018

Parsing the Interferon Transcriptional Network and Its Disease Associations

artículo científico publicado en 2016

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

artículo científico publicado en 2014

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

artículo científico publicado en 2022

Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs

artículo científico publicado en 2020

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

artículo científico publicado en 2013