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A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

artículo científico publicado en 2020

Advances in detecting and reducing off-target effects generated by CRISPR-mediated genome editing

scientific article published on 22 November 2019

Anti-silencing factor 1A is associated with genome stability maintenance of mouse preimplantation embryos†

scientific article published on 01 April 2020

Base editing-mediated splicing correction therapy for spinal muscular atrophy

artículo científico publicado en 2020

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

artículo científico publicado en 2019

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

artículo científico publicado en 2020

Identification of the Sex of Pre-implantation Mouse Embryos Using a Marked Y Chromosome and CRISPR/Cas9

artículo científico publicado en 2019

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

artículo científico publicado en 2019

PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis

artículo científico publicado en 2019

Programmable C-to-U RNA editing using the human APOBEC3A deaminase

artículo científico publicado en 2020

Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

scientific article published on 15 July 2020

The roles of testicular c-kit positive cells in de novo morphogenesis of testis

artículo científico publicado en 2014

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