Lista de obras -

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors

scientific article published in 2018

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors

scholarly article by Letizia Crocetti published in November 2018

2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.

artículo científico publicado en 2016

3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2

artículo científico publicado en 2012

4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists

artículo científico publicado en 2017

6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors

artículo científico publicado en 2009

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice

artículo científico publicado en 2016

A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications

scientific article published on 16 June 2019

Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.

artículo científico publicado en 2015

Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation

artículo científico publicado en 2020

Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.

artículo científico publicado en 2014

Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives

artículo científico

Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.

artículo científico publicado en 2015

Antihypertensive activity of a new c-Jun N-terminal kinase inhibitor in spontaneously hypertensive rats

artículo científico publicado en 2020

Aurantiamide-related dipeptide derivatives are formyl peptide receptor 1 antagonists

scientific article published on 07 October 2019

Botanical polysaccharides: macrophage immunomodulation and therapeutic potential

artículo científico publicado en 2005

Characterization and biological activities of humic substances from mumie.

artículo científico publicado en 2003

Chemical Composition and Antibacterial Activity of Essential Oils from L. Species against Methicillin-Resistant

article

Chemical Composition and Immunomodulatory Activity of Hypericum perforatum Essential Oils

scientific article published on 17 June 2020

Chemical composition and phagocyte immunomodulatory activity of Ferula iliensis essential oils.

artículo científico publicado en 2017

Cinnoline derivatives as human neutrophil elastase inhibitors

artículo científico publicado en 2015

Complement-fixing activity of fulvic acid from Shilajit and other natural sources

artículo científico publicado en 2009

Computational structure-activity relationship analysis of non-peptide inducers of macrophage tumor necrosis factor-alpha production.

artículo científico publicado en 2008

Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors.

artículo científico publicado en 2010

Decomposition of reactive oxygen species by copper(II) bis(1-pyrazolyl)methane complexes

artículo científico publicado en 2006

Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer

artículo científico publicado en 1991

Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase.

artículo científico publicado en 2011

Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition.

artículo científico publicado en 2014

Different metabolic effects of ganglioside GM1 in brain synaptosomes and phagocytic cells

artículo científico publicado en 2002

Electrosprayed poly(lactic-co-glycolic acid) particles as a promising drug delivery system for the novel JNK inhibitor IQ-1

scientific article published on 04 March 2020

Essential Oils from Monarda fistulosa: Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels

scientific article published on 22 October 2020

Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors

artículo científico publicado en 2020

Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita

artículo científico publicado en 2008

Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress

artículo científico publicado en 2017

Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase

artículo científico publicado en 2019

Further studies on 2-arylacetamide pyridazin-3(2H)-ones: Design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists ⬇️

artículo científico publicado el 8 de abril de 2013

Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.

artículo científico publicado en 2010

High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists

artículo científico publicado en 2007

Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors

artículo científico publicado en 2012

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

artículo científico publicado en 2008

Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.

artículo científico publicado en 2009

Immune response to haptenized tumor antigen as possible mechanism of anticancer action of hypoxic bioreductive agents at low doses

artículo científico publicado en 1999

Immunomodulatory activity of acidic polysaccharides isolated from Tanacetum vulgare L.

artículo científico publicado en 2007

Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium

artículo científico publicado en 2009

Immunomodulatory activity of polysaccharides isolated from Alchornea cordifolia ⬇️

artículo científico publicado el 2 de enero de 2013

Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis

artículo científico publicado en 2013

Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum ⬇️

artículo científico publicado el 1 de febrero de 2013

Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems

artículo científico publicado en 2006

Inhibition of Human Neutrophil Responses by the Essential Oil of Artemisia kotuchovii and Its Constituents

artículo científico publicado en 2015

Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70

artículo científico publicado en 2019

Inhibitory effect of IQ-1S, a selective c-Jun N-terminal kinase (JNK) inhibitor, on phenotypical and cytokine-producing characteristics in human macrophages and T-cells

artículo científico publicado en 2020

Isolation of Neutrophils from Nonhuman Species

artículo científico publicado en 2020

Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors

artículo científico publicado en 2017

Lucigenin as a substrate of microsomal NAD(P)H-oxidoreductases.

artículo científico publicado en 1999

Lucigenin luminescence elicited by microsomes and its modulation by nitroazole compounds

scientific article published on 01 November 1999

Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum

artículo científico publicado en 2005

Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha

artículo científico publicado en 2008

Medical drugs from humus matter: Focus on mumie

artículo científico publicado en 2002

Modeling of the anticancer action for radical derivatives of nitroazoles: quantitative structure-activity relationship (QSAR) study.

artículo científico publicado en 2002

Modulation of Human Neutrophil Responses by the Essential Oils from Ferula akitschkensis and Their Constituents

artículo científico publicado en 2016

Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1

artículo científico publicado en 2011

N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase

artículo científico publicado en 2007

Nasal Acai polysaccharides potentiate innate immunity to protect against pulmonary Francisella tularensis and Burkholderia pseudomallei Infections

artículo científico publicado en 2012

Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia

artículo científico publicado en 2020

Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds

artículo científico publicado en 2019

Neutrophil isolation from nonhuman species

artículo científico publicado en 2007

Neutrophil isolation from nonhuman species.

artículo científico publicado en 2014

New 3-unsubstituted isoxazolones as potent human neutrophil elastase inhibitors: Synthesis and molecular dynamic simulation

scientific article published on 04 December 2019

Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism

artículo científico publicado en 2009

Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2

artículo científico publicado en 2014

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors

artículo científico publicado en 2020

Novel formyl peptide receptors (FPRs) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis

scientific article published on 28 April 2020

Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening

scientific article published on 01 August 2006

Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation

artículo científico publicado en 2017

Oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium, enhances IFNγ production by lymphocytes

artículo científico publicado en 2012

Optimization of N-Benzoylindazole Derivatives as Inhibitors of Human Neutrophil Elastase ⬇️

artículo científico publicado el 25 de julio de 2013

Osteoclastic Bone Resorption: Normal and Pathological ⬇️

artículo científico publicado el 15 de diciembre de 1997

Physicochemical Characterization and Antioxidant Activity of Humic Acids Isolated from Peat of Various Origins

Poly(ε-caprolactone) Scaffolds Doped with c-Jun N-terminal Kinase Inhibitors Modulate Phagocyte Activation

scientific article published on 10 October 2019

Polysaccharides derived from Yamoa (Funtumia elastica) prime gammadelta T cells in vitro and enhance innate immune responses in vivo

artículo científico publicado en 2009

Polysaccharides isolated from Açaí fruit induce innate immune responses

artículo científico publicado en 2011

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats.

artículo científico publicado en 2019

Quantitative structure-activity relationships for small non-peptide antagonists of CXCR2: indirect 3D approach using the frontal polygon method.

artículo científico publicado en 2005

Role of NADPH oxidase in formation and function of multinucleated giant cells

artículo científico publicado en 2009

Sanazole as substrate of xanthine oxidase and microsomal NADPH/cytochrome P450 reductase

scientific article published on 01 December 2001

Structure-activity relationship analysis of N-benzoylpyrazoles for elastase inhibitory activity: a simplified approach using atom pair descriptors

artículo científico publicado en 2008

Suppression by radiosensitizer AK-2123 of early phorbol myristate acetate-stimulated chemiluminescence response of human neutrophils induced by gamma-irradiation (short communication)

artículo científico publicado en 1998

Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors.

artículo científico publicado en 2016

Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors

artículo científico publicado en 2017

Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists.

artículo científico publicado en 2016

Synthesis, HPLC enantioresolution, and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists.

artículo científico publicado en 2013

Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25

artículo científico publicado en 2019

Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors

article

Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors.

artículo científico publicado en 2018

Synthesis, characterization and potent superoxide dismutase-like activity of novel bis(pyrazole)-2,2'-bipyridyl mixed ligand copper(II) complexes

artículo científico publicado en 2009

Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists

artículo científico publicado en 2012

The luminol-amplified chemiluminescence of neutrophils and monocytes in patients with gastric cancer after intraoperative radiotherapy using radiosensitizer sanazole

artículo científico publicado en 1999

The natural sesquiterpene lactones arglabin, grosheimin, agracin, parthenolide, and estafiatin inhibit T cell receptor (TCR) activation

artículo científico publicado en 2017

Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis

artículo científico publicado en 2020

Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed)

artículo científico publicado en 2016

[JUN N-TERMINAL KINASES AND THEIR PHARMACOLOGICAL MODULATION OF ISCHE-MIC AND REPERFUSION INJURY OF THE BRAIN]

scientific article published on 01 March 2017

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury

scientific article published on 05 July 2018

Lista de obras de

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors

2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.

3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2

4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists

6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice

A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications

Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.

Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation

Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.

Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives

Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.

Antihypertensive activity of a new c-Jun N-terminal kinase inhibitor in spontaneously hypertensive rats

Aurantiamide-related dipeptide derivatives are formyl peptide receptor 1 antagonists

Botanical polysaccharides: macrophage immunomodulation and therapeutic potential

Characterization and biological activities of humic substances from mumie.

Chemical Composition and Antibacterial Activity of Essential Oils from L. Species against Methicillin-Resistant

Chemical Composition and Immunomodulatory Activity of Hypericum perforatum Essential Oils

Chemical composition and phagocyte immunomodulatory activity of Ferula iliensis essential oils.

Cinnoline derivatives as human neutrophil elastase inhibitors

Complement-fixing activity of fulvic acid from Shilajit and other natural sources

Computational structure-activity relationship analysis of non-peptide inducers of macrophage tumor necrosis factor-alpha production.

Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors.

Decomposition of reactive oxygen species by copper(II) bis(1-pyrazolyl)methane complexes

Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer

Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase.

Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition.

Different metabolic effects of ganglioside GM1 in brain synaptosomes and phagocytic cells

Electrosprayed poly(lactic-co-glycolic acid) particles as a promising drug delivery system for the novel JNK inhibitor IQ-1

Essential Oils from Monarda fistulosa: Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels

Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors

Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita

Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress

Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase

Further studies on 2-arylacetamide pyridazin-3(2H)-ones: Design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists ⬇️

Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.

High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists

Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.

Immune response to haptenized tumor antigen as possible mechanism of anticancer action of hypoxic bioreductive agents at low doses

Immunomodulatory activity of acidic polysaccharides isolated from Tanacetum vulgare L.

Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium

Immunomodulatory activity of polysaccharides isolated from Alchornea cordifolia ⬇️

Immunomodulatory activity of polysaccharides isolated from Clerodendrum splendens: beneficial effects in experimental autoimmune encephalomyelitis

Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum ⬇️

Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems

Inhibition of Human Neutrophil Responses by the Essential Oil of Artemisia kotuchovii and Its Constituents

Inhibition of T Cell Receptor Activation by Semi-Synthetic Sesquiterpene Lactone Derivatives and Molecular Modeling of Their Interaction with Glutathione and Tyrosine Kinase ZAP-70

Inhibitory effect of IQ-1S, a selective c-Jun N-terminal kinase (JNK) inhibitor, on phenotypical and cytokine-producing characteristics in human macrophages and T-cells

Isolation of Neutrophils from Nonhuman Species

Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors

Lucigenin as a substrate of microsomal NAD(P)H-oxidoreductases.

Lucigenin luminescence elicited by microsomes and its modulation by nitroazole compounds

Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum

Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha

Medical drugs from humus matter: Focus on mumie

Modeling of the anticancer action for radical derivatives of nitroazoles: quantitative structure-activity relationship (QSAR) study.

Modulation of Human Neutrophil Responses by the Essential Oils from Ferula akitschkensis and Their Constituents

Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1

N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase

Nasal Acai polysaccharides potentiate innate immunity to protect against pulmonary Francisella tularensis and Burkholderia pseudomallei Infections

Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia

Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds

Neutrophil isolation from nonhuman species

Neutrophil isolation from nonhuman species.

New 3-unsubstituted isoxazolones as potent human neutrophil elastase inhibitors: Synthesis and molecular dynamic simulation

Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism

Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors

Novel formyl peptide receptors (FPRs) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis

Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening

Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation

Oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium, enhances IFNγ production by lymphocytes

Optimization of N-Benzoylindazole Derivatives as Inhibitors of Human Neutrophil Elastase ⬇️

Osteoclastic Bone Resorption: Normal and Pathological ⬇️

Physicochemical Characterization and Antioxidant Activity of Humic Acids Isolated from Peat of Various Origins

Poly(ε-caprolactone) Scaffolds Doped with c-Jun N-terminal Kinase Inhibitors Modulate Phagocyte Activation