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5.17 Chemoimmunotherapy Improves Survival of Patients with Chronic Lymphocytic Leukemia

5.40 Rituximab Maintenance in Patients with Chronic Lymphocytic Leukemia after First-Line Treatment with Rituximab plus Fludarabine, Cyclophosphamide, and Mitoxantrone: Final Results of a Multicenter Phase II Trial on Behalf of the Spanish CLL Study

article

A Distributed International Patient Data Registry for Hairy Cell Leukemia

A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia

article

ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances

artículo científico publicado en 2002

Abdominal computed tomography predicts progression in patients with Rai stage 0 chronic lymphocytic leukemia.

artículo científico publicado en 2007

Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes

artículo científico publicado en 2004

Allogeneic Stem-Cell Transplantation May Overcome the Adverse Prognosis of UnmutatedVHGene in Patients With Chronic Lymphocytic Leukemia

article published in 2005

Analysis of criteria for treatment initiation in patients with progressive chronic lymphocytic leukemia

artículo científico publicado en 2018

Anemia associated with impaired erythropoietin secretion after allogeneic stem cell transplantation: incidence, risk factors, and response to treatment

artículo científico publicado en 2008

Appropriateness of applying the response criteria for multiple myeloma to Waldenstrom's macroglobulinemia?

artículo científico publicado el 1 de abril de 2003

Autoimmune cytopenia in chronic lymphocytic leukaemia: diagnosis and treatment

artículo científico publicado en 2011

Autoimmune cytopenia in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance

artículo científico publicado el 24 de agosto de 2010

Autologous stem cell transplantation for patients with active Hodgkin's lymphoma: Long-term outcome of 61 patients from a single institution

artículo científico publicado en 2007

B cell activation through CD40 and IL4R ligation modulates the response of chronic lymphocytic leukaemia cells to BAFF and APRIL.

artículo científico publicado en 2013

B cell activator factor and a proliferation-inducing ligand at the cross-road of chronic lymphocytic leukemia and autoimmunity

artículo científico publicado en 2009

Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling

artículo científico publicado en 2008

Bortezomib: an effective agent in extramedullary disease in multiple myeloma

artículo científico publicado en 2006

CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients

artículo científico publicado en 2003

CD34+-enriched–CD19+-depleted autologous peripheral blood stem cell transplantation for chronic lymphoproliferative disorders

artículo científico publicado en 2002

CD49d (ITGA4) expression is a predictor of time to first treatment in patients with chronic lymphocytic leukaemia and mutatedIGHVstatus

artículo científico publicado en 2015

CDK4andMDM2Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-typeINK4a/ARFLocus

article

CLL and COVID-19 at the Hospital Clinic of Barcelona: an interim report

scientific article published on 19 May 2020

COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

artículo científico publicado en 2021

Case-control comparison of at-home to total hospital care for autologous stem-cell transplantation for hematologic malignancies.

artículo científico publicado en 2006

Changes in clinical stage identify patients with CLL and different outcome within iwCLL partial response: RESONATE study

article

Chronic Lymphocytic Leukemia: New Concepts for Future Therapy

artículo científico publicado el 1 de octubre de 2010

Chronic lymphocytic leukemia and autoimmunity: a systematic review

artículo científico publicado el 17 de enero de 2011

Chronic lymphocytic leukemia in the elderly: clinico-biological features, outcomes, and proposal of a prognostic model

artículo científico publicado en 2014

Chronic lymphocytic leukemia therapy: beyond chemoimmunotherapy.

artículo científico publicado en 2012

Chronic lymphocytic leukemia: A prognostic model comprising only two biomarkers (IGHV mutational status and FISH cytogenetics) separates patients with different outcome and simplifies the CLL-IPI.

artículo científico publicado en 2017

Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies.

artículo científico publicado en 2005

Clinical Practice Recommendations for Use of Allogeneic Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation

artículo científico publicado en 2016

Clinical factors influencing T-cell receptor excision circle (TRECs) counts following allogeneic stem cell transplantation in adults

artículo científico publicado en 2006

Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma

artículo científico publicado en 2003

Clinical implications of ZAP-70 expressionin chronic lymphocytic leukemia

artículo científico publicado en 2006

Clinical significance of minimal residual disease, as assessed by different techniques, after stem cell transplantation for chronic lymphocytic leukemia.

artículo científico publicado en 2006

Clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-cell lymphomas

artículo científico publicado en 2004

Clonal T-cell populations and increased risk for cytotoxic T-cell lymphomas in B-CLL patients: clinicopathologic observations and molecular analysis

artículo científico publicado en 2004

Collection of Philadelphia-negative stem cells using recombinant human granulocyte colony-stimulating factor in chronic myeloid leukemia patients treated with alpha-interferon

artículo científico publicado en 2002

Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia.

artículo científico publicado en 2011

Comment on "Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors"

artículo científico publicado en 2012

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation

article

Comparative genomic hybridisation identifies two variants of smoldering multiple myeloma

artículo científico publicado en 2005

Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

artículo científico publicado en 2016

Critical molecular pathways in CLL therapy.

artículo científico publicado en 2018

Cytotoxic effects of B lymphocytes mediated by reactive oxygen species

artículo científico publicado en 2004

Detection of Aspergillus galactomannan by enzyme immunoabsorbent assay in recipients of allogeneic hematopoietic stem cell transplantation: a prospective study

scientific article published on 01 April 2004

Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations.

artículo científico publicado en 2012

Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction

artículo científico publicado en 2005

Diffuse large B-cell lymphoma: clinical and biological characterization and outcome according to the nodal or extranodal primary origin

artículo científico publicado en 2005

Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation

artículo científico publicado en 2006

Efficacy and tolerability of danazol as a treatment for the anaemia of myelofibrosis with myeloid metaplasia: long-term results in 30 patients

artículo científico publicado en 2005

Enteropathy-associated T-cell lymphoma: clinical and histological findings from the international peripheral T-cell lymphoma project.

artículo científico publicado en 2011

Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior

artículo científico publicado en 2010

Extramedullary multiple myeloma escapes the effect of thalidomide.

artículo científico publicado en 2004

Familial lymphoid neoplasms in patients with mantle cell lymphoma.

artículo científico publicado en 2004

FcγRIIb expression in early stage chronic lymphocytic leukemia.

artículo científico publicado en 2017

FcγRIIb-BCR co-ligation inhibits BCR signaling in chronic lymphocytic leukemia

scientific article published on 26 March 2020

Feasibility and results of autologous stem cell transplantation in de novo acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocol

artículo científico publicado en 2004

Fingertip cellulitis after fingerstick for capillary microhematocrit measurement in a patient with chronic lymphocytic leukemia: an uncommom infectious complication

artículo científico publicado en 2002

Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2003

Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia

artículo científico publicado en 2002

Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication

artículo científico publicado en 2008

Follicular lymphoma in early stages: high risk of relapse and usefulness of the Follicular Lymphoma International Prognostic Index to predict the outcome of patients

artículo científico publicado en 2006

Follicular lymphoma international prognostic index.

artículo científico publicado en 2004

Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM.

artículo científico publicado en 2009

Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasms

artículo científico publicado en 2004

Gene expression profile and genomic changes in disease progression of early-stage chronic lymphocytic leukemia

article

Gene expression profiling in chronic lymphocytic leukaemia

scientific article published on June 2009

Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression.

artículo científico publicado en 2006

Genetic imbalances in progressed B-cell chronic lymphocytic leukemia and transformed large-cell lymphoma (Richter's syndrome)

artículo científico publicado en 2002

Genetic lesions in chronic lymphocytic leukemia: clinical implications

artículo científico publicado en 2009

Genetic lesions in chronic lymphocytic leukemia: what's ready for prime time use?

artículo científico publicado en 2010

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia

artículo científico publicado en 2008

Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma

article

Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.

artículo científico publicado en 2006

Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene

article

Guidelines for diagnosis, indications for treatment, response assessment and supportive management of chronic lymphocytic leukemia.

artículo científico publicado en 2018

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

artículo científico publicado en 2008

Hematopoiesis-related microRNA expression in myelodysplastic syndromes.

artículo científico publicado en 2009

Hepatitis C virus and GBV-C virus prevalence among patients with B-cell lymphoma in different European regions: a case-control study of the International Extranodal Lymphoma Study Group.

artículo científico publicado en 2011

High clinical and molecular response rates with fludarabine, cyclophosphamide and mitoxantrone in previously untreated patients with advanced stage follicular lymphoma.

artículo científico publicado en 2008

High levels of chromosomal imbalances in typical and small-cell variants of T-cell prolymphocytic leukemia

artículo científico publicado en 2003

High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma.

artículo científico publicado en 2006

High numbers of tumor-infiltrating programmed cell death 1-positive regulatory lymphocytes are associated with improved overall survival in follicular lymphoma.

artículo científico publicado en 2009

High-dose infusional ifosfamide, etoposide plus methylprednisolone followed by dexamethasone, high-dose ara-C and cisplatinum and autologous stem cell transplantation for refractory or relapsed aggressive non-Hodgkin's lymphoma.

artículo científico publicado en 2002

High-risk chronic lymphocytic leukemia in the era of pathway inhibitors: integrating molecular and cellular therapies

scientific article published on 11 July 2018

Hope for high-risk chronic lymphocytic leukemia relapsing after allogeneic stem-cell transplantation

artículo científico publicado en 2015

How I treat refractory CLL.

artículo científico publicado en 2005

How We Manage Patients With Chronic Lymphocytic Leukemia During the SARS-CoV-2 Pandemic

scientific article published on 30 July 2020

IGHV gene insertions and deletions in chronic lymphocytic leukemia: "CLL-biased" deletions in a subset of cases with stereotyped receptors

artículo científico publicado en 2006

Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells

artículo científico publicado en 2008

Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms

artículo científico publicado en 2005

Improving survival in patients with chronic lymphocytic leukemia (1980-2008): the Hospital Clinic of Barcelona experience

artículo científico publicado en 2009

Incidence and clinical significance of bcl-2/IgH rearrangements in follicular lymphoma.

artículo científico publicado en 2003

Increased incidence of acute myeloid leukemia after liver transplantation? Description of three new cases and review of the literature

artículo científico publicado en 2004

Induction of histone H1.2 cytosolic release in chronic lymphocytic leukemia cells after genotoxic and non-genotoxic treatment

artículo científico publicado en 2008

Initial Clinico-Biological Characteristics and Follow-up Data of Elderly Patients With Chronic Lymphocytic Leukemia (CLL): A Retrospective Analysis of a Series of 364 Cases

Initial features and outcome of cutaneous and non-cutaneous primary extranodal follicular lymphoma.

artículo científico publicado en 2011

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

artículo científico publicado en 2016

Interleukin 6 and tumour necrosis factor alpha serum levels in monoclonal gammopathy of undetermined significance

artículo científico publicado en 2002

International Prognostic Score for Asymptomatic Early-stage Chronic Lymphocytic Leukemia

artículo científico publicado en 2020

International and Italian prognostic indices in follicular lymphoma.

artículo científico publicado en 2003

International network of cancer genome projects

artículo científico publicado en 2010

Kinetics of recovery of dendritic cell subsets after reduced-intensity conditioning allogeneic stem cell transplantation and clinical outcome

artículo científico publicado en 2007

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy

artículo científico publicado en 2006

Leukemic involvement is a common feature in mantle cell lymphoma

artículo científico publicado en 2007

Limitations of Gallium-67 SPECT in histological transformation of chronic lymphocytic leukaemia: an analysis of 13 patients with clinically suspected Richter's syndrome

scientific article published on 01 November 2002

Low-dose total-body irradiation and fludarabine followed by hematopoietic cell transplantation from HLA-identical sibling donors do not induce complete T-cell donor engraftment in most patients with progressive hematologic diseases

artículo científico publicado en 2003

MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis

artículo científico publicado en 2014

Maintenance therapy in chronic lymphocytic leukaemia

scientific article published on 01 August 2016

Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents?

artículo científico publicado en 2014

Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation

artículo científico publicado en 2006

Mechanism of action and resistance to monoclonal antibody therapy

artículo científico publicado en 2003

MicroRNA expression in chronic lymphocytic leukemia developing autoimmune hemolytic anemia

scientific article published on 29 January 2013

MicroRNA expression profiling in classic Hodgkin lymphoma

artículo científico publicado en 2007

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

artículo científico publicado en 2003

NOTCH1 mutations in chronic lymphocytic leukemia with trisomy 12

New Developments in Chronic Lymphocytic Leukaemia Diagnosis

New prognostic markers in chronic lymphocytic leukemia

artículo científico publicado en 2008

New treatment options for chronic lymphocytic leukemia.

artículo científico

Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival

artículo científico

Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia

artículo científico publicado en 2015

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

artículo científico publicado en 2006

Perspectives on the use of new diagnostic tools in the treatment of chronic lymphocytic leukemia

artículo científico publicado en 2005

Predicting the outcome of patients with chronic lymphocytic leukemia: Progress and uncertainty

scientific article published on 05 August 2019

Present and future of personalized medicine in CLL.

artículo científico publicado en 2016

Reduced-intensity conditioning regimen preserves thymic function in the early period after hematopoietic stem cell transplantation

artículo científico publicado en 2005

Refining prognostic factors in chronic lymphocytic leukemia

artículo científico publicado en 2002

Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma.

artículo científico publicado en 2009

Reliability of six prognostic models to predict time-to-first-treatment in patients with chronic lymphocytic leukaemia in early phase.

artículo científico publicado en 2017

Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project

artículo científico publicado en 2018

Response to thalidomide in multiple myeloma: impact of angiogenic factors

artículo científico publicado en 2004

Results of syngeneic hematopoietic stem cell transplantation for acute leukemia: risk factors for outcomes of adults transplanted in first complete remission

artículo científico publicado en 2008

Risk factors for acute graft-versus-host disease in patients undergoing transplantation with CD34+ selected blood cells from HLA-identical siblings

artículo científico publicado en 2002

Rituximab maintenance after first-line therapy with rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) for chronic lymphocytic leukemia

artículo científico publicado en 2013

Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.

artículo científico publicado en 2009

Rituximab-based chemoimmunotherapy prolongs survival of patients with chronic lymphocytic leukemia independently of the time of administration.

artículo científico publicado en 2013

Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma

artículo científico publicado en 2003

Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature

artículo científico publicado en 2007

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2002

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

artículo científico publicado en 2005

The role of stem-cell transplantation in chronic lymphocytic leukemia risk-adapted therapy

artículo científico publicado en 2007

Treatment of Chronic Lymphocytic Leukemia With del(17p)/TP53 Mutation: Allogeneic Hematopoietic Stem Cell Transplantation or BCR-Signaling Inhibitors?

artículo científico publicado en 2016

Treatment of primary acute myeloid leukemia: results of a prospective multicenter trial including high-dose cytarabine or stem cell transplantation as post-remission strategy

artículo científico publicado en 2004

Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation

artículo científico publicado en 2004

Unrelated donor marrow transplantation for B-cell chronic lymphocytic leukemia after using myeloablative conditioning: results from the Center for International Blood and Marrow Transplant research

artículo científico publicado en 2005

Where does allogeneic stem cell transplantation fit in the treatment of chronic lymphocytic leukemia?

artículo científico

XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells.

artículo científico publicado en 2014

ZAP-70 Expression in Normal Pro/Pre B Cells, Mature B Cells, and in B-Cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2006

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

artículo científico publicado en 2003

[Autologous haematopoietic stem cell transplantation in POEMS syndrome: results in 4 cases]

artículo científico publicado en 2007

p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

artículo científico publicado en 2009