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2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase

artículo científico publicado en 2003

Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases

artículo científico publicado en 2003

Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation

artículo científico publicado en 2011

Carotid artery wall mechanics in young males with high cardiorespiratory fitness

artículo científico publicado en 2018

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.

artículo científico publicado en 2013

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

artículo científico publicado en 2004

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

artículo científico publicado en 2004

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

artículo científico publicado en 2011

Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease

artículo científico publicado en 2015

Ectopic lipid storage in non-alcoholic fatty liver disease is not mediated by impaired mitochondrial oxidative capacity in skeletal muscle

article

Endothelial dysfunction in hyperandrogenic polycystic ovary syndrome is not explained by either obesity or ectopic fat deposition

artículo científico publicado en 2014

Exercise training improves cutaneous microvascular function in nonalcoholic fatty liver disease

artículo científico publicado en 2013

Exercise training in polycystic ovarian syndrome enhances flow-mediated dilation in the absence of changes in fatness

artículo científico publicado en 2013

Exercise training reverses endothelial dysfunction in nonalcoholic fatty liver disease

artículo científico publicado en 2014

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

scientific journal article

MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)

artículo científico publicado en 2009

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma

article

Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology

artículo científico publicado en 2006

Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis

artículo científico publicado en 2002

Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance.

artículo científico publicado en 2012

Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex

artículo científico publicado en 2002

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis

artículo científico publicado en 2010

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases

artículo científico publicado en 2013

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

artículo científico publicado en 2002

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

artículo científico publicado en 2003

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

scientific article published on 03 December 2019

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin

artículo científico publicado en 2004

The influence of habitual endurance exercise on carotid artery strain and strain-rate in young and middle-aged men

artículo científico publicado en 2020

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

artículo científico publicado en 2002