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A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice

artículo científico publicado en 2022

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

artículo científico publicado en 2018

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

artículo científico publicado en 2014

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

artículo científico publicado en 2014

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

artículo científico publicado en 2019

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

artículo científico publicado en 2017

Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency

artículo científico publicado en 2020

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

artículo científico publicado en 2013

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 02 December 2019

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

artículo científico publicado en 2020

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

artículo científico publicado en 2021

Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.

artículo científico publicado en 2018

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques

artículo científico publicado en 2017

HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.

artículo científico publicado en 2018

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

scientific article published on 30 January 2020

HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies

artículo científico publicado en 2017

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

artículo científico publicado en 2015

HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria

artículo científico publicado en 2014

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers

scientific article published on 15 July 2019

IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria

artículo científico publicado en 2014

Immune checkpoint modulation enhances HIV-1 antibody induction

artículo científico publicado en 2020

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

artículo científico publicado en 2016

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations

artículo científico publicado en 2017

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

scientific article published on April 2016

Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants

artículo científico publicado en 2020

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

artículo científico publicado en 2016

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

artículo científico publicado en 2022

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 17 September 2019

Polyreactivity and autoreactivity among HIV-1 antibodies

artículo científico publicado en 2014

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

artículo científico publicado en 2017

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation

artículo científico publicado en 2014

Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies

scientific article published in Nature Communications

Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage

artículo científico publicado en 2019

Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

artículo científico publicado en 2017

Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee

artículo científico publicado en 2015

Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

artículo científico publicado en 2022

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

artículo científico publicado en 2019

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

artículo científico publicado en 2016

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

article

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

artículo científico publicado en 2017

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

artículo científico publicado en 2013