Lista de obras - Yuan-Tsong Chen - Dominio Público Uruguay

A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defect

artículo científico publicado en 2006

A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians

artículo científico publicado en 2006

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

artículo científico publicado en 2017

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese

scientific journal article

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

artículo científico publicado en 2011

A genome-wide survey of copy number variations in Han Chinese residing in Taiwan

artículo científico publicado en 2009

A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene

artículo científico publicado en 2009

A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan

artículo científico publicado en 2008

A new analysis tool for individual-level allele frequency for genomic studies

artículo científico publicado en 2010

A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders

artículo científico publicado en 2013

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

artículo científico publicado en 2005

A prospective study of HLA*B-5801 genotyping in preventing allopurinol- induced severe cutaneous adverse reactions

artículo científico publicado en 2014

A recent update of pharmacogenomics in drug-induced severe skin reactions

artículo científico publicado en 2011

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

artículo científico publicado en 2008

Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.

artículo científico publicado en 2012

Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice

artículo científico publicado en 2011

An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays

artículo científico publicado en 2016

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin

artículo científico publicado en 2016

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

artículo científico publicado en 2017

Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension

artículo científico publicado en 2014

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan ⬇️

artículo científico publicado el 24 de marzo de 2011

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease.

artículo científico publicado en 2009

Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese

artículo científico publicado en 2010

Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease

artículo científico publicado en 2006

Correlations between the enantio- and regio-selective metabolisms of warfarin

artículo científico publicado en 2016

Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation.

artículo científico publicado en 2015

De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay

artículo científico publicado en 2013

Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses

artículo científico publicado en 2014

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

artículo científico publicado en 2012

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

scientific journal article

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

scientific journal article

FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization.

artículo científico publicado en 2006

Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies

artículo científico publicado en 2017

Functional analysis of novel SNPs and mutations in human and mouse genomes

artículo científico publicado en 2008

Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis

artículo científico publicado en 2010

Genetic determinants of warfarin dosing in the Han-Chinese population

artículo científico publicado en 2009

Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects

artículo científico publicado en 2013

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

artículo científico publicado en 2010

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

artículo científico publicado en 2006

GenoWatch: a disease gene mining browser for association study

artículo científico publicado en 2008

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

artículo científico publicado en 2016

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

artículo científico publicado en 2016

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

artículo científico publicado en 2016

Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan

artículo científico publicado en 2017

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations

artículo científico publicado en 2013

Genome-wide association study of treatment refractory schizophrenia in Han Chinese

scientific journal article

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan

artículo científico publicado en 2009

Genome-wide expression profiles of subchondral bone in osteoarthritis

artículo científico publicado en 2013

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

artículo científico publicado en 2019

Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease

artículo científico publicado en 2005

Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder

artículo científico publicado en 2010

Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.

artículo científico publicado en 2010

Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis

article

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

artículo científico publicado en 2007

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

artículo científico publicado en 2005

Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations

article

Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa

scientific journal article

Human leukocyte antigens and drug hypersensitivity

artículo científico publicado en 2007

Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study

artículo científico publicado en 2016

Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers

artículo científico publicado en 2013

Identification of functional single nucleotide polymorphisms in the branchpoint site

artículo científico publicado en 2017

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study

scientific journal article

Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study

artículo científico publicado en 2016

Inter-individual differences in baseline coagulation activities and their implications for international normalized ratio control during warfarin initiation therapy.

artículo científico publicado en 2012

Intragenic microdeletion of RUNX2 is a novel mechanism for cleidocranial dysplasia

artículo científico publicado en 2008

Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia

artículo científico publicado en 2017

Long contiguous stretches of homozygosity in the human genome

artículo científico publicado en 2006

Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans

artículo científico publicado en 2018

MPDA: microarray pooled DNA analyzer

artículo científico publicado en 2008

Mapping human genetic diversity in Asia

artículo científico publicado en 2009

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

artículo científico publicado en 2016

Medical genetics: a marker for Stevens-Johnson syndrome

artículo científico publicado en 2004

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

artículo científico publicado en 2012

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

artículo científico publicado en 2011

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

artículo científico publicado en 2010

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome

artículo científico publicado en 2010

Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan

artículo científico publicado en 2011

Mouse model of glycogen storage disease type III.

artículo científico publicado en 2014

Mutations in the SLC2A10 gene cause arterial abnormalities in mice

artículo científico publicado en 2008

Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population

artículo científico publicado en 2009

Novel susceptibility gene for nonfamilial hypokalemic periodic paralysis

artículo científico publicado en 2016

Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein

artículo científico publicado en 2010

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

artículo científico publicado en 2016

Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model

artículo científico publicado en 2014

Pharmacogenetic dosing of warfarin in the Han-Chinese population: a randomized trial

artículo científico publicado en 2017

Pharmacogenetics of toxic epidermal necrolysis.

artículo científico publicado en 2010

Pharmacogenomics for personalized pain medicine

artículo científico publicado en 2016

Pharmacogenomics of adverse drug reactions: implementing personalized medicine

artículo científico publicado en 2012

Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project

artículo científico publicado en 2016

Predicting HLA genotypes using unphased and flanking single-nucleotide polymorphisms in Han Chinese population

artículo científico publicado en 2014

PrimerZ: streamlined primer design for promoters, exons and human SNPs

artículo científico publicado en 2007

Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis

artículo científico publicado en 2016

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility

artículo científico publicado en 2013

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

artículo científico publicado en 2012

SAQC: SNP array quality control

artículo científico publicado en 2011

SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes

artículo científico publicado en 2010

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

artículo científico publicado en 2011

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

artículo científico publicado en 2012

Type II collagen gene variants and inherited osteonecrosis of the femoral head

artículo científico publicado en 2005

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study

artículo científico publicado en 2015

Use of the Biopharmaceutics Drug Disposition Classification System (BDDCS) to Help Predict the Occurrence of Idiosyncratic Cutaneous Adverse Drug Reactions Associated with Antiepileptic Drug Usage

artículo científico publicado en 2016

VKORC1 haplotypes in five East-Asian populations and Indians

artículo científico publicado en 2009

Variant GADL1 and response to lithium therapy in bipolar I disorder

artículo científico publicado en 2013

VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era.

artículo científico publicado en 2012

Lista de obras de Yuan-Tsong Chen

A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defect

A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes

A genome-wide survey of copy number variations in Han Chinese residing in Taiwan

A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene

A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan

A new analysis tool for individual-level allele frequency for genomic studies

A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

A prospective study of HLA*B-5801 genotyping in preventing allopurinol- induced severe cutaneous adverse reactions

A recent update of pharmacogenomics in drug-induced severe skin reactions

AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.

Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen storage disease type III.

Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice

An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan ⬇️

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease.

Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese

Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease

Correlations between the enantio- and regio-selective metabolisms of warfarin

Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation.

De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay

Determinants of the over-anticoagulation response during warfarin initiation therapy in Asian patients based on population pharmacokinetic-pharmacodynamic analyses

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization.

Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies

Functional analysis of novel SNPs and mutations in human and mouse genomes

Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis

Genetic determinants of warfarin dosing in the Han-Chinese population

Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.

GenoWatch: a disease gene mining browser for association study

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan

Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations

Genome-wide association study of treatment refractory schizophrenia in Han Chinese

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan

Genome-wide expression profiles of subchondral bone in osteoarthritis

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

Glucose tetrasaccharide as a biomarker for monitoring the therapeutic response to enzyme replacement therapy for Pompe disease

Glycogen storage disease type IV: novel mutations and molecular characterization of a heterogeneous disorder

Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.

Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations

Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa

Human leukocyte antigens and drug hypersensitivity

Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study

Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers

Identification of functional single nucleotide polymorphisms in the branchpoint site

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study

Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study

Inter-individual differences in baseline coagulation activities and their implications for international normalized ratio control during warfarin initiation therapy.

Intragenic microdeletion of RUNX2 is a novel mechanism for cleidocranial dysplasia

Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia

Long contiguous stretches of homozygosity in the human genome

Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans

MPDA: microarray pooled DNA analyzer

Mapping human genetic diversity in Asia

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

Medical genetics: a marker for Stevens-Johnson syndrome

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome

Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan