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"Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase

artículo científico publicado en 2017

: a comparative study with human GNE.

artículo científico publicado en 2018

A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products

artículo científico publicado en 2004

Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase

artículo científico publicado en 2002

An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells

Antibacterial drug leads: DNA and enzyme multitargeting

artículo científico publicado en 2015

Binding Modes of Zaragozic Acid A to Human Squalene Synthase and Staphylococcal Dehydrosqualene Synthase

artículo científico publicado en 2012

Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates

artículo científico publicado en 2010

Binding mode of the oxidized α-anomer of NAD+ to RSP, a Rex-family repressor

artículo científico publicado en 2015

Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

artículo científico publicado en 2007

Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton

artículo científico publicado en 2003

Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-β-endoglucanase from Thielavia terrestris.

artículo científico publicado en 2017

Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance

artículo científico publicado en 2011

Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism

artículo científico publicado en 2010

Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans

scientific article published on 03 January 2020

Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase.

artículo científico publicado en 2017

Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination ⬇️

artículo científico publicado el 15 de noviembre de 2003

Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase fromSaccharomyces cerevisiaeand the Mechanism of Product Chain Length Determination

artículo científico publicado en 2006

Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation

artículo científico publicado en 2007

Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris

artículo científico publicado en 2010

Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase

artículo científico publicado en 2021

Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides

artículo científico publicado en 2010

Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5

artículo científico publicado en 2012

Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima

artículo científico publicado en 2011

Crystal structure of D-aminoacylase from Alcaligenes faecalis DA1. A novel subset of amidohydrolases and insights into the enzyme mechanism

artículo científico publicado en 2003

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis

artículo científico publicado en 2008

Crystal structure of LepI, a multifunctional SAM-dependent enzyme which catalyzes pericyclic reactions in leporin biosynthesis

scientific article published on 01 February 2019

Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus) ⬇️

artículo científico publicado el 1 de marzo de 2004

Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: implications in virion assembly and immunogenicity

artículo científico publicado en 2006

Crystal structure of the blue fluorescent protein with a Leu-Leu-Gly tri-peptide chromophore derived from the purple chromoprotein of Stichodactyla haddoni

scientific article published on 02 March 2019

Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins

artículo científico publicado en 2007

Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein

artículo científico publicado en 2013

Crystal structure of vespid phospholipase A(1) reveals insights into the mechanism for cause of membrane dysfunction

artículo científico publicado en 2015

Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution

artículo científico publicado en 2003

Crystal structures of Bacillus alkaline phytase in complex with divalent metal ions and inositol hexasulfate

artículo científico publicado en 2011

Crystal structures of Staphylococcal SaeR reveal possible DNA-binding modes

artículo científico publicado en 2016

Crystal structures of d-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars

artículo científico publicado en 2012

Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation

artículo científico publicado en 2005

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase fromEscherichia colireveal the catalytic and chain-length determining mechanisms ⬇️

artículo científico publicado en 2015

Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons

artículo científico publicado en 2005

Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins

artículo científico publicado en 2004

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis

artículo científico publicado en 2005

Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosis

artículo científico publicado en 2014

Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp. subtilis strain 168.

artículo científico publicado en 2012

Crystallization and preliminary X-ray diffraction analysis of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485

artículo científico publicado en 2012

Crystallization and preliminary X-ray diffraction analysis of a novel β-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum.

artículo científico publicado en 2014

Crystallization and preliminary X-ray diffraction analysis of the S-adenosylhomocysteine hydrolase (SAHH) from Thermotoga maritima

artículo científico publicado en 2014

Current Progresses in Phytase Research: Three-Dimensional Structure and Protein Engineering

Design and characterization of a multimeric DNA binding protein using Sac7d and GCN4 as templates

artículo científico publicado en 2005

Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues

artículo científico publicado en 2002

Dietary Flavonoids Luteolin and Quercetin Inhibit Migration and Invasion of Squamous Carcinoma through Reduction of Src/Stat3/S100A7 Signaling

scientific article published on 15 November 2019

Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes

artículo científico publicado en 2014

Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose

artículo científico publicado en 2011

Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase

artículo científico publicado en 2006

Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop

artículo científico publicado en 2012

Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions

artículo científico publicado en 2010

Enzymatic characterization and crystal structure analysis of Chlamydomonas reinhardtii dehydroascorbate reductase and their implications for oxidative stress

artículo científico publicado en 2017

Functional and structural analyses of a 1,4-β-endoglucanase from Ganoderma lucidum

artículo científico publicado en 2016

Functional and structural studies of pullulanase from Anoxybacillus sp. LM18-11.

artículo científico

Head-to-Head Prenyl Synthases in Pathogenic Bacteria

artículo científico publicado en 2017

Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures

artículo científico publicado en 2005

Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions

scientific article published on 17 May 2019

Immunological, structural, and preliminary X-ray diffraction characterizations of the fusion core of the SARS-coronavirus spike protein

artículo científico publicado en 2004

Improving specific activity and thermostability of Escherichia coli phytase by structure-based rational design.

artículo científico publicado en 2014

Improving the catalytic performance of a GH11 xylanase by rational protein engineering

artículo científico publicado en 2015

Improving the specific activity of β-mannanase from Aspergillus niger BK01 by structure-based rational design

artículo científico publicado en 2014

Inactive S298R disassembles the dodecameric L-aspartate 4-decarboxylase into dimers

artículo científico publicado en 2008

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates: A Crystallographic and Computational Investigation †

artículo científico publicado en 2008

Insights into TIM-Barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB fromBacillus subtilisandStaphylococcus aureus

artículo científico publicado en 2013

Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes

artículo científico publicado en 2012

Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis

artículo científico publicado en 2016

Mechanism of action and inhibition of dehydrosqualene synthase

artículo científico publicado en 2010

Mechanism of the maturation process of SARS-CoV 3CL protease

artículo científico publicado en 2005

Modulation of Substrate Specificities of d-Sialic Acid Aldolase through Single Mutations of Val-251 ⬇️

artículo científico publicado el 26 de enero de 2011

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.

artículo científico publicado en 2016

NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius.

artículo científico publicado en 2018

Neisseria conserved hypothetical protein DMP12 is a DNA mimic that binds to histone-like HU protein ⬇️

artículo científico publicado el 26 de marzo de 2013

Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor

artículo científico publicado en 2012

Preliminary X-ray diffraction analysis of a thermophilic β-1,3-1,4-glucanase from Clostridium thermocellum

artículo científico publicado en 2014

Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli

artículo científico publicado en 2003

Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase from Escherichia coli.

artículo científico publicado en 2013

Preliminary X-ray diffraction analysis of thermostable β-1,4-xylanase from Streptomyces sp. S9.

artículo científico publicado en 2013

Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d

artículo científico publicado en 2005

Protein S-Thiolation by Glutathionylspermidine (Gsp): THE ROLE OF ESCHERICHIA COLI Gsp SYNTHETASE/AMIDASE IN REDOX REGULATION

artículo científico publicado en 2010

Purification, crystallization and preliminary X-ray analysis of immunogenic virus-like particles formed by infectious bursal disease virus (IBDV) structural protein VP2.

artículo científico publicado en 2003

Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-β-d-glucanase ⬇️

artículo científico publicado el 30 de septiembre de 2011

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

Roles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolase

artículo científico publicado en 2014

SH3-like motif-containing C-terminal domain of staphylococcal teichoic acid transporter suggests possible function

artículo científico publicado en 2016

Squalene synthase as a target for Chagas disease therapeutics

artículo científico publicado en 2014

Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor

artículo científico publicado en 2014

Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

artículo científico publicado en 2009

Structural Insights to the Heterotetrameric Interaction between the Vibrio parahaemolyticus PirAvp and PirBvp Toxins and Activation of the Cry-Like Pore-Forming Domain.

artículo científico publicado en 2019

Structural analyses and yeast production of the β-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellum

artículo científico publicado en 2015

Structural analysis of a glycoside hydrolase family 11 xylanase from Neocallimastix patriciarum: insights into the molecular basis of a thermophilic enzyme.

artículo científico publicado en 2014

Structural analysis of the antibiotic-recognition mechanism of MarR proteins ⬇️

artículo científico publicado el 16 de mayo de 2013

Structural and Functional Analyses of Five Conserved Positively Charged Residues in the L1 and N-Terminal DNA Binding Motifs of Archaeal RadA Protein

artículo científico publicado en 2007

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

artículo científico publicado en 2017

Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485

artículo científico publicado en 2013

Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production

artículo científico publicado en 2014

Structural and mutagenetic analyses of a 1,3-1,4-β-glucanase from Paecilomyces thermophila

artículo científico publicado en 2014

Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2

artículo científico publicado en 2008

Structural basis for fragmenting the exopolysaccharide of Acinetobacter baumannii by bacteriophage ΦAB6 tailspike protein

artículo científico publicado en 2017

Structural basis for the antibody neutralization ofHerpes simplex virus

artículo científico publicado en 2013

Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range

artículo científico publicado en 2010

Structural characterization of borneol dehydrogenase from Pseudomonas sp. TCU-HL1

artículo científico publicado en 2020

Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis

artículo científico publicado en 2017

Structural insight into catalytic mechanism of PET hydrolase

artículo científico publicado en 2017

Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-β-1,4-xylanase

artículo científico publicado en 2016

Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase

artículo científico publicado en 2020

Structural insights into enzymatic degradation of oxidized polyvinyl alcohol

artículo científico publicado en 2014

Structural insights into the catalytic mechanism of human squalene synthase

artículo científico publicado en 2014

Structural insights of the ssDNA binding site in the multifunctional endonuclease AtBFN2 from Arabidopsis thaliana.

artículo científico publicado en 2014

Structural perspectives of an engineered β-1,4-xylanase with enhanced thermostability

artículo científico publicado en 2014

Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis

artículo científico publicado en 2010

Structure and Function of a "Head-to-Middle" Prenyltransferase: Lavandulyl Diphosphate Synthase.

artículo científico publicado en 2016

Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

artículo científico publicado en 2014

Structure and Mechanism of an Arabidopsis Medium/Long-Chain-Length Prenyl Pyrophosphate Synthase

artículo científico publicado en 2011

Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.

artículo científico publicado en 2007

Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase

artículo científico publicado en 2015

Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase

artículo científico publicado en 2003

Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation

artículo científico publicado en 2010

Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec.

artículo científico publicado en 2006

Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding

artículo científico publicado en 2009

Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii

artículo científico publicado en 2018

Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase.

artículo científico publicado en 2016

Structure, assembly, and mechanism of a PLP-dependent dodecameric L-aspartate beta-decarboxylase

artículo científico publicado en 2009

Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum

artículo científico publicado en 2014

Structure, mechanism and function of prenyltransferases

artículo científico publicado en 2002

Structure-Based Inhibitors Exhibit Differential Activities againstHelicobacter pyloriandEscherichia coliUndecaprenyl Pyrophosphate Synthases

artículo científico publicado en 2008

Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms.

artículo científico publicado en 2015

Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets

artículo científico publicado en 2016

Structures of human MST3 kinase in complex with adenine, ADP and Mn2+

artículo científico publicado en 2010

Structures of the hyperthermophilic chromosomal protein Sac7d in complex with DNA decamers

scientific article published on 21 July 2004

Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies

artículo científico publicado en 2004

Substrate binding of a GH5 endoglucanase from the ruminal fungusPiromyces rhizinflata

artículo científico publicado en 2011

Substrate binding to a GH131 β-glucanase catalytic domain from Podospora anserina

artículo científico publicado en 2013

Substrate-analogue complex structure of Mycobacterium tuberculosis decaprenyl diphosphate synthase

scientific article published on 13 March 2019

Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase

artículo científico publicado en 2022

Terpyridine Platinum(II) Complexes Inhibit Cysteine Proteases by Binding to Active-site Cysteine ⬇️

artículo científico publicado el 1 de octubre de 2011

Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1

artículo científico publicado en 2009

The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium

artículo científico publicado en 2002

The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA

artículo científico publicado en 2017

The Hexameric Structures of Human Heat Shock Protein 90 ⬇️

artículo científico publicado el 25 de mayo de 2011

The Refined Crystal Structure of an Eel Pout Type III Antifreeze Protein RD1 at 0.62-Å Resolution Reveals Structural Microheterogeneity of Protein and Solvation

artículo científico publicado en 2003

The T4 phage DNA mimic protein Arn inhibits the DNA binding activity of the bacterial histone-like protein H-NS.

artículo científico publicado en 2014

The monomeric form of Neisseria DNA mimic protein DMP19 prevents DNA from binding to the histone-like HU protein

artículo científico publicado en 2017

The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin

artículo científico publicado en 2015

The structural interpretations of residue Ser297 in catalytic efficiency of Escherichia coli phenylalanine aminotransferase

artículo científico publicado en 2003

The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485

artículo científico publicado en 2012

Three New Structures of Left-Handed RadA Helical Filaments: Structural Flexibility of N-Terminal Domain Is Critical for Recombinase Activity

artículo científico publicado en 2009

Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase

artículo científico publicado en 2014

Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase

scientific article published on 02 April 2019

Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase

artículo científico publicado en 2016

White spot syndrome virus protein ICP11: A histone-binding DNA mimic that disrupts nucleosome assembly

artículo científico publicado en 2008

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