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2016 ATVB Plenary Lecture: Receptor for Advanced Glycation Endproducts and Implications for the Pathogenesis an Treatment of Cardiometabolic Disorders: Spotlight on the Macrophage

artículo científico publicado en 2017

2346: Receptor for advanced glycation end-products: Mitigating the persistent effects of particulate matter induced airway injury

A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis

artículo científico publicado en 2019

A novel monoclonal antibody for RAGE-directed imaging identifies accelerated atherosclerosis in diabetes

artículo científico publicado en 2009

AGE/RAGE produces endothelial dysfunction in coronary arterioles in type 2 diabetic mice

artículo científico publicado en 2008

Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice

artículo científico publicado en 2010

Advanced Glycation End Product Recognition by the Receptor for AGEs

artículo científico publicado en 2011

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

artículo científico publicado en 2002

Advanced Glycation End Products: Building on the Concept of the "Common Soil" in Metabolic Disease

artículo científico publicado en 2020

Advanced Glycation Endproducts and the Accelerated Atherosclerosis in Diabetes

Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages

artículo científico publicado en 2010

Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation

artículo científico publicado en 2005

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.

artículo científico publicado en 2004

Advanced glycation end products in diabetic cardiomyopathy: an alternative hypothesis

artículo científico publicado en 2011

Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway

artículo científico publicado en 2004

Advanced glycation end products on stored red blood cells increase endothelial reactive oxygen species generation through interaction with receptor for advanced glycation end products

artículo científico publicado en 2010

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway.

artículo científico publicado en 2017

Advanced glycation end products: sparking the development of diabetic vascular injury

artículo científico publicado en 2006

Advanced glycation endproducts: from precursors to RAGE: round and round we go.

artículo científico publicado en 2010

AgeR deletion decreases soluble fms-like tyrosine kinase 1 production and improves post-ischemic angiogenesis in uremic mice

scientific article published on 23 September 2020

Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice

artículo científico publicado en 2017

Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.

artículo científico publicado en 2016

Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats. ⬇️

artículo científico publicado en 2010

Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury

artículo científico publicado en 2005

Aldose reductase drives hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals.

artículo científico publicado en 2013

Aldose reductase modulates acute activation of mesenchymal markers via the β-catenin pathway during cardiac ischemia-reperfusion.

artículo científico publicado en 2017

Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury.

artículo científico publicado en 2011

Aldose reductase, oxidative stress and diabetic cardiovascular complications

artículo científico publicado en 2012

Alterations in ventricular K(ATP) channel properties during aging

artículo científico publicado en 2012

Alternative splicing of RAGE: roles in biology and disease

artículo científico publicado en 2011

Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene

artículo científico publicado en 2009

Alternatively spliced RAGEv1 inhibits tumorigenesis through suppression of JNK signaling

artículo científico publicado en 2010

Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants

scientific article published on 22 August 2018

An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation

artículo científico publicado en 2020

Analysis of the role of the conserved disulfide in amyloid formation by human IAPP in homogenous and heterogeneous environments.

artículo científico publicado en 2018

Annual Report on Sex in Preclinical Studies: Arteriosclerosis, Thrombosis, and Vascular Biology Publications in 2018

artículo científico publicado en 2019

Antagonism of RAGE suppresses peripheral nerve regeneration

artículo científico publicado en 2004

Anti-receptor for advanced glycation end products therapies as novel treatment for abdominal aortic aneurysm

artículo científico publicado en 2009

Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts

artículo científico publicado en 2007

Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: the Northern Manhattan Study (NOMAS)

artículo científico publicado en 2011

At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products

artículo científico publicado en 2005

Beneficial Effect of Glucose Control on Atherosclerosis Progression in Diabetic ApoE(-/-) Mice: Shown by Rage Directed Imaging.

artículo científico publicado en 2014

Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products

artículo científico publicado en 2004

Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice

artículo científico publicado en 2004

Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice

artículo científico publicado en 2008

Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders

artículo científico publicado en 2003

Blockade of the receptor for advanced glycation end products attenuates acetaminophen-induced hepatotoxicity in mice

artículo científico publicado en 2006

Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice

artículo científico publicado en 2013

Cellular mechanisms and consequences of glycation in atherosclerosis and obesity

artículo científico publicado en 2016

Central role for aldose reductase pathway in myocardial ischemic injury

artículo científico publicado en 2004

Central role of PKCbeta in neointimal expansion triggered by acute arterial injury.

artículo científico publicado en 2005

Central role of RAGE-dependent neointimal expansion in arterial restenosis

artículo científico publicado en 2003

Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling.

artículo científico publicado en 2016

Chronic low-dose rapamycin treatment fine tunes cardioprotective signalling in ischaemia-reperfused diabetic hearts

artículo científico publicado en 2020

Chronic vascular inflammation in patients with type 2 diabetes: endothelial biopsy and RT-PCR analysis.

artículo científico publicado en 2005

Combinatorial library of improved peptide aptamers, CLIPs to inhibit RAGE signal transduction in mammalian cells.

artículo científico publicado en 2013

Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility

article

Controllable expansion of primary cardiomyocytes by reversible immortalization

artículo científico publicado en 2009

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

artículo científico publicado en 2004

Deletion of the formin Diaph1 protects from structural and functional abnormalities in the murine diabetic kidney

scientific article published on 22 August 2018

Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse

artículo científico publicado en 2010

Development of receptor for advanced glycation end products-directed imaging of atherosclerotic plaque in a murine model of spontaneous atherosclerosis.

artículo científico publicado en 2008

Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE.

artículo científico publicado en 2017

Diabetes Mellitus and Cardiovascular Disease

scientific article published on 01 April 2019

Diabetes and oral disease: implications for health professionals

artículo científico publicado en 2012

Diabetes, leukoencephalopathy and rage

artículo científico publicado en 2006

Diabetic vascular disease: it's all the RAGE.

artículo científico publicado en 2005

Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease

artículo científico publicado en 2018

Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.

artículo científico publicado en 2015

Differential impact of diabetes and hypertension in the brain: adverse effects in grey matter

artículo científico publicado en 2011

Differential impact of diabetes and hypertension in the brain: adverse effects in white matter

article by Christina Yang et al published June 2011 in Neurobiology of Disease

Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation

artículo científico publicado en 2003

Editorial

artículo científico publicado en 2007

Enhanced expression of receptor for advanced glycation end products in chronic kidney disease

artículo científico publicado en 2004

Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?

artículo científico publicado en 2016

Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways.

artículo científico publicado en 2012

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy

artículo científico publicado en 2003

Glycation & the RAGE axis: targeting signal transduction through DIAPH1.

artículo científico publicado en 2016

Glycation and insulin resistance: novel mechanisms and unique targets?

artículo científico publicado en 2012

Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond

artículo científico publicado en 2003

Highlighting Diabetes Mellitus: The Epidemic Continues

artículo científico publicado en 2018

Human Vascular Endothelial Cells: A Model System for Studying Vascular Inflammation in Diabetes and Atherosclerosis ⬇️

artículo científico publicado el 1 de junio de 2011

Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein E-/- mice

artículo científico publicado en 2011

Human immunodeficiency virus type 2 DNA vaccine provides partial protection from acute baboon infection

artículo científico publicado en 2004

Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis

artículo científico publicado en 2013

Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia

artículo científico publicado en 2007

Identification, classification, and expression of RAGE gene splice variants

artículo científico publicado en 2007

Imaging RAGE expression in atherosclerotic plaques in hyperlipidemic pigs

artículo científico publicado en 2014

Imaging VEGF Receptors and αvβ3 Integrins in a Mouse Hindlimb Ischemia Model of Peripheral Arterial Disease.

artículo científico publicado en 2018

Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury

artículo científico publicado en 2012

Imaging receptor for advanced glycation end product expression in mouse model of hind limb ischemia

artículo científico publicado en 2013

Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes

artículo científico publicado en 2011

Impaired slow axonal transport in diabetic peripheral nerve is independent of RAGE.

artículo científico publicado en 2013

Incense Burning is Associated with Human Oral Microbiota Composition

scientific article published on 11 July 2019

Increased expression of the receptor for advanced glycation end-products in human peripheral neuropathies

artículo científico publicado en 2013

Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice.

artículo científico publicado en 2006

Infection with a periodontal pathogen increases mononuclear cell adhesion to human aortic endothelial cells.

artículo científico publicado en 2006

Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products.

artículo científico publicado en 2005

Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice.

artículo científico publicado en 2009

Influence of ischemic injury on vein graft remodeling: role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation.

artículo científico publicado en 2005

Insulin resistance and metabolic syndrome: mechanisms and consequences

artículo científico publicado en 2012

Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42

artículo científico publicado en 2008

Interstitial deletion of chromosome 12q: genotype-phenotype correlation of two patients utilizing array comparative genomic hybridization.

artículo científico publicado en 2005

Intra-coronary administration of soluble receptor for advanced glycation end-products attenuates cardiac remodeling with decreased myocardial transforming growth factor-beta1 expression and fibrosis in minipigs with ischemia-reperfusion injury.

artículo científico publicado en 2010

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

artículo científico publicado en 2015

Islet amyloid polypeptide toxicity and membrane interactions

artículo científico publicado en 2013

Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: With Stops Along the Way in the Lung, Heart, Blood Vessels, and Adipose Tissue

scientific article published on 17 December 2020

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity

artículo científico publicado en 2020

Lipid–Drug Association Enhanced HIV-1 Protease Inhibitor Indinavir Localization in Lymphoid Tissues and Viral Load Reduction: A Proof of Concept Study in HIV-2287-Infected Macaques ⬇️

artículo científico publicado el 1 de diciembre de 2003

Lysophosphatidic acid and apolipoprotein A1 predict increased risk of developing World Trade Center-lung injury: a nested case-control study

artículo científico publicado en 2014

Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling

artículo científico publicado en 2012

Macrophages: much more than big eaters!

scientific article published on 02 May 2013

Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells

artículo científico publicado en 2005

Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications

artículo científico publicado en 2008

Mechanisms of islet amyloidosis toxicity in type 2 diabetes

artículo científico publicado en 2013

Mechanisms of transcription factor acetylation and consequences in hearts.

artículo científico publicado en 2016

Metabolic dysfunction in Emirati subjects in Abu Dhabi: Relationship to levels of soluble RAGEs

scientific article published on 23 April 2019

Metabolism, Obesity, and Diabetes Mellitus

scientific article published on 26 June 2019

Methylglyoxal comes of AGE.

artículo científico publicado en 2006

Mice deficient in PKCbeta and apolipoprotein E display decreased atherosclerosis

artículo científico publicado en 2008

MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging

artículo científico publicado en 2021

Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome

article published in 2021

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1<sup>G93A</sup> murine model of amyotrophic lateral sclerosis in a sex-dependent manner

artículo científico publicado en 2021

Morphological Changes and Immunohistochemical Expression of RAGE and its Ligands in the Sciatic Nerve of Hyperglycemic Pig (Sus Scrofa)

artículo científico publicado en 2010

Multiomics of World Trade Center particulate matter-induced persistent airway hyperreactivity: role of receptor for advanced glycation end products

artículo científico publicado en 2020

Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet

artículo científico publicado en 2017

Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity

artículo científico publicado en 2019

Neuronal RAGE expression modulates severity of injury following transient focal cerebral ischemia

artículo científico publicado en 2008

Neuronal-glial communication perturbations in murine SOD1<sup>G93A</sup> spinal cord

artículo científico publicado en 2022

Novel role for aldose reductase in mediating acute inflammatory responses in the lung

artículo científico publicado en 2009

Opposing roles of RAGE and Myd88 signaling in extensive liver resection

artículo científico publicado en 2011

Oral infection with a periodontal pathogen accelerates early atherosclerosis in apolipoprotein E-null mice

artículo científico publicado en 2003

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products

scientific journal article

PKCbeta modulates ischemia-reperfusion injury in the heart

artículo científico publicado en 2008

PKCbeta regulates ischemia/reperfusion injury in the lung

artículo científico publicado en 2004

Patterns of tobacco use in the United Arab Emirates Healthy Future (UAEHFS) pilot study.

artículo científico publicado en 2018

Peripheral venous congestion causes inflammation, neurohormonal, and endothelial cell activation

artículo científico publicado en 2013

Peroxisome proliferator-activated receptor gamma down-regulates receptor for advanced glycation end products and inhibits smooth muscle cell proliferation in a diabetic and nondiabetic rat carotid artery injury model

scientific journal article

Polyol pathway and RAGE: a central metabolic and signaling axis in diabetic complications

scientific article published on 01 January 2010

Population-Level Prediction of Type 2 Diabetes From Claims Data and Analysis of Risk Factors.

artículo científico publicado en 2015

Porphyromonas gingivalis induces its uptake by human macrophages and promotes foam cell formation in vitro

artículo científico publicado en 2004

Porphyromonas gingivalis infection and cell death in human aortic endothelial cells.

artículo científico publicado en 2007

Porphyromonas gingivalis infection and prothrombotic effects in human aortic smooth muscle cells

artículo científico publicado en 2008

Protein glycation: a firm link to endothelial cell dysfunction

artículo científico publicado en 2004

Protein kinase C beta/early growth response-1 pathway: a key player in ischemia, atherosclerosis, and restenosis

artículo científico publicado en 2006

RAGE Mediates Cholesterol Efflux Impairment in Macrophages Caused by Human Advanced Glycated Albumin

artículo científico publicado en 2020

RAGE Signaling Significantly Impacts Tumorigenesis and Hepatic Tumor Growth in Murine Models of Colorectal Carcinoma ⬇️

artículo científico publicado el 8 de septiembre de 2010

RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes

artículo científico publicado en 2015

RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways

artículo científico publicado en 2007

RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling

artículo científico publicado en 2005

RAGE and its ligands in retinal disease

artículo científico publicado en 2007

RAGE and its ligands: a lasting memory in diabetic complications?

artículo científico publicado en 2004

RAGE and modulation of ischemic injury in the diabetic myocardium

artículo científico publicado en 2008

RAGE and the pathogenesis of chronic kidney disease

artículo científico publicado en 2010

RAGE axis: Animal models and novel insights into the vascular complications of diabetes

artículo científico publicado en 2004

RAGE binds C1q and enhances C1q-mediated phagocytosis.

artículo científico publicado en 2012

RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.

artículo científico publicado en 2018

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

artículo científico publicado en 2002

RAGE deficiency improves postinjury sciatic nerve regeneration in type 1 diabetic mice

artículo científico publicado en 2012

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy

artículo científico publicado en 2003

RAGE expression in human T cells: a link between environmental factors and adaptive immune responses

artículo científico publicado en 2012

RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer

artículo científico publicado en 2011

RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism ⬇️

artículo científico publicado en 2020

RAGE ligand upregulation of VEGF secretion in ARPE-19 cells.

artículo científico publicado en 2007

RAGE ligation affects T cell activation and controls T cell differentiation

artículo científico publicado en 2008

RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB

artículo científico publicado en 2005

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

artículo científico publicado en 2003

RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis

artículo científico

RAGE mediates vascular injury and inflammation after global cerebral ischemia

artículo científico publicado en 2011

RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways.

artículo científico publicado en 2010

RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model

artículo científico publicado en 2008

RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways

scientific article published on 01 December 2004

RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes

artículo científico publicado en 2005

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

artículo científico publicado en 2004

RAGE regulates the metabolic and inflammatory response to high-fat feeding in mice

artículo científico publicado en 2014

RAGE, glomerulosclerosis and proteinuria: roles in podocytes and endothelial cells.

artículo científico publicado en 2009

RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis

artículo científico publicado en 2017

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease

artículo científico publicado en 2009

RAGE-mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs)

scientific article published on 01 March 2002

RAGE: a journey from the complications of diabetes to disorders of the nervous system - striking a fine balance between injury and repair.

artículo científico publicado en 2005

RAGE: a novel biological and genetic marker for vascular disease.

scientific article published on April 2009

RAGE: a novel target for drug intervention in diabetic vascular disease

artículo científico publicado en 2004

RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease

artículo científico publicado en 2007

RAGE: exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes

scientific article published on January 2007

RAGE: therapeutic target and biomarker of the inflammatory response--the evidence mounts

artículo científico publicado en 2009

Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond.

scientific article published on October 2013

Randomized pilot trial of bariatric surgery versus intensive medical weight management on diabetes remission in type 2 diabetic patients who do NOT meet NIH criteria for surgery and the role of soluble RAGE as a novel biomarker of success

artículo científico publicado en 2014

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

artículo científico publicado en 2012

Recent highlights of ATVB: diabetes mellitus

artículo científico publicado en 2014

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response

artículo científico publicado en 2009

Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury

artículo científico publicado en 2003

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications

artículo científico publicado en 2011

Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response.

artículo científico publicado en 2007

Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

artículo científico publicado en 2020

Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral Sclerosis.

artículo científico publicado en 2015

Receptor for Advanced Glycation End Products is Involved in Platelet Hyperactivation and Arterial Thrombosis during Chronic Kidney Disease

artículo científico publicado en 2020

Receptor for Advanced Glycation Endproducts (RAGE): A Formidable Force in the Pathogenesis of the Cardiovascular Complications of Diabetes & Aging

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging

artículo científico publicado en 2007

Receptor for advanced glycation end product (RAGE)-dependent modulation of early growth response-1 in hepatic ischemia/reperfusion injury.

artículo científico publicado en 2009

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

artículo científico publicado en 2008

Receptor for advanced glycation end products (RAGE) and implications for the pathophysiology of heart failure

artículo científico publicado en 2012

Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress

artículo científico publicado en 2007

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

artículo científico publicado en 2004

Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy

artículo científico publicado en 2007

Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation.

artículo científico publicado en 2014

Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis

artículo científico publicado en 2005

Receptor for advanced glycation end products and its ligands: initiators or amplifiers of joint inflammation--a bit of both?

scientific article published on 01 January 2006

Receptor for advanced glycation end products and the cardiovascular complications of diabetes and beyond: lessons from AGEing

artículo científico publicado en 2006

Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo

scientific article published on 01 December 2007

Receptor for advanced glycation end products on human synovial fibroblasts: role in the pathogenesis of dialysis-related amyloidosis

artículo científico publicado en 2002

Receptor for advanced glycation end products: a key molecule in the genesis of chronic kidney disease vascular calcification and a potential modulator of sodium phosphate co-transporter PIT-1 expression

scientific article published on 01 December 2019

Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis

artículo científico publicado en 2008

Receptor for advanced glycation end-products (RAGE) modulates neutrophil adhesion and migration on glycoxidated extracellular matrix

scientific article published on 01 December 2008

Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: a case-cohort study and murine model of acute particulate exposure

artículo científico publicado en 2017

Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes

artículo científico publicado en 2002

Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes

artículo científico publicado en 2002

Receptor for advanced glycation endproducts mediates pro-atherogenic responses to periodontal infection in vascular endothelial cells

artículo científico publicado en 2010

Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings

artículo científico publicado en 2002

Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury

artículo científico publicado en 2006

Reduced expression of Munc13-1 in human and porcine diabetic peripheral nerve.

artículo científico publicado en 2013

Reporting Sex and Sex Differences in Preclinical Studies

artículo científico publicado en 2018

Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council"

artículo científico publicado en 2018

S100/calgranulins EN-RAGEing the blood vessels: implications for inflammatory responses and atherosclerosis

artículo científico publicado en 2011

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus

artículo científico publicado en 2020

S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular smooth muscle cells is dependent on PLD2.

artículo científico publicado en 2003

S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)

artículo científico publicado en 2004

S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis

scientific article published on 20 June 2012

Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20

artículo científico publicado en 2011

Signal Transduction in Receptor for Advanced Glycation End Products (RAGE): SOLUTION STRUCTURE OF C-TERMINAL RAGE (ctRAGE) AND ITS BINDING TO mDia1

artículo científico publicado en 2012

Signal transduction in receptor for advanced glycation end products (RAGE)

scientific article published in 2012

Signaling of Serum Amyloid A Through Receptor for Advanced Glycation End Products as a Possible Mechanism for Uremia-Related Atherosclerosis.

artículo científico publicado en 2016

Skin autofluorescence, 5-year mortality, and cardiovascular events in peripheral arterial disease: all that glitters is surely not gold

artículo científico publicado en 2014

Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction

artículo científico publicado en 2016

Soluble Levels of Receptor for Advanced Glycation Endproducts (sRAGE) and Coronary Artery Disease

scientific article published on 01 May 2005

Soluble RAGE Treatment Delays Progression of Amyotrophic Lateral Sclerosis in SOD1 Mice.

artículo científico publicado en 2016

Soluble RAGE: a hot new biomarker for the hot joint?

artículo científico publicado en 2005

Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging

artículo científico publicado en 2010

Soluble RAGEs - Prospects for treating & tracking metabolic and inflammatory disease

artículo científico publicado en 2015

Soluble Receptor for Advanced Glycation End Products Improves Stromal Cell-Derived Factor-1 Activity in Model Diabetic Environments

artículo científico publicado en 2016

Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation

artículo científico publicado en 2008

Sphingosine-1-phosphate: waging a battle in the diabetic blood vessel

artículo científico publicado en 2006

Stopping the primal RAGE reaction in myocardial infarction: capturing adaptive responses to heal the heart?

artículo científico publicado en 2008

Su1868 Dissecting the Role of RAGE in Intestinal Fibrosis

Suppression of RAGE as a basis of simvastatin-dependent plaque stabilization in type 2 diabetes

artículo científico publicado en 2006

Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system

artículo científico publicado en 2003

Tempering the wrath of RAGE: an emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation

artículo científico publicado en 2009

Temporal reliability of serum soluble and endogenous secretory receptors for advanced glycation end-products (sRAGE and esRAGE) in healthy women

artículo científico publicado en 2018

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

artículo científico publicado en 2017

The AGE-RAGE axis in an Arab population: The United Arab Emirates Healthy Futures (UAEHFS) pilot study

artículo científico publicado en 2017

The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury.

artículo científico publicado en 2017

The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study.

artículo científico publicado en 2005

The RAGE axis and endothelial dysfunction: maladaptive roles in the diabetic vasculature and beyond

artículo científico publicado en 2005

The RAGE axis in early diabetic retinopathy

artículo científico publicado en 2005

The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature

artículo científico publicado en 2010

The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system

scientific article published on 20 March 2019

The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration

scientific article published on 24 January 2018

The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies.

artículo científico publicado en 2018

The Semaphorin 3E/PlexinD1 axis regulates macrophage inflammation in obesity

artículo científico publicado en 2013

The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals

artículo científico publicado en 2018

The association between mediators of the receptor for advanced glycation end product (RAGE) axis and immune checkpoint inhibitor (ICI)–induced colitis in patients with melanoma.

artículo científico publicado en 2022

The biology of RAGE and its ligands: uncovering mechanisms at the heart of diabetes and its complications

artículo científico publicado en 2007

The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes.

artículo científico

The expression of the receptor for glycation endproducts (RAGE) in oral squamous cell carcinomas

artículo científico publicado en 2008

The ligand/RAGE axis: lighting the fuse and igniting vascular stress

artículo científico publicado en 2006

The multiple faces of RAGE--opportunities for therapeutic intervention in aging and chronic disease

artículo científico publicado en 2016

The next generation of RAGE modulators: implications for soluble RAGE therapies in vascular inflammation

artículo científico publicado en 2013

The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli

artículo científico publicado en 2009

The rationale and design of the personal diet study, a randomized clinical trial evaluating a personalized approach to weight loss in individuals with pre-diabetes and early-stage type 2 diabetes

artículo científico publicado en 2019

The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control

artículo científico publicado en 2003

The receptor for advanced glycation end products (RAGE) affects T cell differentiation in OVA induced asthma

artículo científico publicado en 2014

The receptor for advanced glycation end products (RAGE) and DIAPH1: unique mechanisms and healing the wounded vascular system

article

The receptor for advanced glycation end products mediates lung endothelial activation by RBCs

artículo científico publicado en 2012

The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease

artículo científico publicado en 2009

The role of RAGE in amyloid-beta peptide-mediated pathology in Alzheimer's disease.

artículo científico publicado en 2009

The role of RAGE in the pathogenesis of intestinal barrier dysfunction after hemorrhagic shock

artículo científico publicado en 2006

Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials

scientific article published on May 2009

Three-year follow-up comparing metabolic surgery versus medical weight management in patients with type 2 diabetes and BMI 30-35. The role of sRAGE biomarker as predictor of satisfactory outcomes.

artículo científico publicado en 2016

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.

scientific article published on 23 May 2016

Treatment effect with anti-RAGE F(ab')2 antibody improves hind limb angiogenesis and blood flow in Type 1 diabetic mice with left femoral artery ligation

artículo científico publicado en 2015

Types of tobacco consumption and the oral microbiome in the United Arab Emirates Healthy Future (UAEHFS) Pilot Study

artículo científico publicado en 2018

Ultrastructural features of retinal capillary basement membrane thickening in diabetic swine

artículo científico publicado en 2010

Unlocking the biology of RAGE in diabetic microvascular complications

artículo científico publicado en 2013

Upregulation of RAGE and its ligands in proliferative retinal disease

artículo científico publicado en 2005

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice

artículo científico publicado en 2008

Vascular endothelial sampling and analysis of gene transcripts: a new quantitative approach to monitor vascular inflammation

artículo científico publicado en 2007

sRAGE induces human monocyte survival and differentiation

artículo científico publicado en 2010

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