Lista de obras - Nicole Doria-Rose - Dominio Público Uruguay

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

scientific article published on 01 September 2019

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

artículo científico publicado en 2012

AIDS Vaccine 2005

artículo científico publicado en 2005

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

scientific article published on 11 October 2019

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

artículo científico publicado en 2020

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

artículo científico publicado en 2019

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

scholarly article by Nicole Doria-Rose published in 2021

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding ⬇️

artículo científico publicado el 6 de junio de 2012

Antibody-secreting B cells in HIV infection

artículo científico publicado en 2009

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

artículo científico publicado en 2009

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

artículo científico publicado en 2019

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

artículo científico publicado en 2012

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

artículo científico publicado en 2017

Characterization of the Neutralizing Antibody Response in a Case of Genetically Linked HIV Superinfection

article

Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells

artículo científico publicado en 2012

Coevolution of HIV-1 and broadly neutralizing antibodies

scientific article published on 01 July 2019

Comprehensive analysis of unique cases with extraordinary control over HIV replication

artículo científico publicado en 2012

Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

article

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

Cytotoxic Capacity of SIV-Specific CD8+ T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques ⬇️

artículo científico publicado el 28 de febrero de 2013

DNA vaccine strategies: candidates for immune modulation and immunization regimens.

artículo científico publicado en 2003

Defining the risk of SARS-CoV-2 variants on immune protection

artículo científico publicado en 2022

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

artículo científico publicado en 2013

Development of a 3Mut-Apex-Stabilized Envelope Trimer that Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

scientific article published on 15 April 2020

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

artículo científico publicado en 2020

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

artículo científico publicado en 2021

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

artículo científico publicado en 2021

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

artículo científico publicado en 2016

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

artículo científico publicado en 2014

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

artículo científico publicado en 2018

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

artículo científico publicado en 2020

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

artículo científico publicado en 2011

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

artículo científico publicado en 2008

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

artículo científico publicado en 2016

Glycan-dependent HIV-specific neutralizing antibodies bind to cells of uninfected individuals

artículo científico publicado en 2019

Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

artículo científico publicado en 2018

HIV Immunology Goes Out On a Limb

artículo científico publicado en 2016

HIV neutralizing antibodies: clinical correlates and implications for vaccines

artículo científico publicado en 2010

HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate

artículo científico publicado en 2017

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

scientific article published on 01 April 2020

HIV-1 Gag p17 presented as virus-like particles on the E2 scaffold from Geobacillus stearothermophilus induces sustained humoral and cellular immune responses in the absence of IFNγ production by CD4+ T cells.

artículo científico publicado en 2010

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins ⬇️

artículo científico publicado el 8 de agosto de 2012

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

article

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

scientific article published on 01 August 2019

HIV-1 gp120-CD4-Induced Antibody Complex Elicits CD4 Binding Site-Specific Antibody Response in Mice

scientific article published on 17 February 2020

HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

artículo científico publicado en 2012

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

artículo científico publicado en 2016

Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature

artículo científico publicado en 2020

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

artículo científico publicado en 2015

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

artículo científico publicado en 2016

Isolation of human monoclonal antibodies from peripheral blood B cells

artículo científico publicado en 2013

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

artículo científico publicado en 2019

Limited anti-HIV neutralizing antibody breadth and potency before and after HIV superinfection in Danish men who have sex with men

article

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

scientific article published on 01 February 2020

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

artículo científico publicado en 2017

Multigene DNA prime-boost vaccines for SHIV89.6P

article

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

artículo científico publicado en 2016

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs

artículo científico publicado en 2018

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound

artículo científico publicado en 2020

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

artículo científico publicado en 2015

Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies

scientific article published on January 2017

Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation

scientific article published on 01 November 2019

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

artículo científico publicado en 2020

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

artículo científico publicado en 2020

Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir

artículo científico publicado en 2019

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

artículo científico publicado en 2016

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes

article

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

artículo científico publicado en 2018

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

artículo científico publicado en 2010

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2020

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

artículo científico publicado en 2013

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

artículo científico publicado en 2020

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

artículo científico publicado en 2020

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

artículo científico publicado en 2020

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

artículo científico publicado en 2019

Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial

scientific article published on 28 August 2019

Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site ⬇️

artículo científico publicado el 14 de marzo de 2012

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

scientific article published in Nature Communications

Sequential immunization with a subtype B HIV-1 envelope quasispecies partially mimics the in vivo development of neutralizing antibodies

artículo científico publicado en 2011

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

artículo científico publicado en 2016

Strategies to guide the antibody affinity maturation process

artículo científico publicado en 2015

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

artículo científico publicado en 2014

Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation

article

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition

article

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

artículo científico publicado en 2013

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

scientific article published on 01 April 2020

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

artículo científico publicado en 2017

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

artículo científico publicado en 2018

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells

scientific article published on 12 December 2019

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

artículo científico publicado en 2017

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

artículo científico publicado en 2018

Use of Enzyme-digested Virus-like Particles as Probes for Flow Cytometric Sorting of HIV-specific Neutralizing Ab-producing B-cells.

artículo científico publicado en 2014

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage

artículo científico publicado en 2020

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

artículo científico publicado en 2021

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

artículo científico publicado en 2015

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies.

artículo científico publicado en 2014

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2015

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Lista de obras de Nicole Doria-Rose

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

AIDS Vaccine 2005

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding ⬇️

Antibody-secreting B cells in HIV infection

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

Characterization of the Neutralizing Antibody Response in a Case of Genetically Linked HIV Superinfection

Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells

Coevolution of HIV-1 and broadly neutralizing antibodies

Comprehensive analysis of unique cases with extraordinary control over HIV replication

Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Cytotoxic Capacity of SIV-Specific CD8+ T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques ⬇️

DNA vaccine strategies: candidates for immune modulation and immunization regimens.

Defining the risk of SARS-CoV-2 variants on immune protection

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

Development of a 3Mut-Apex-Stabilized Envelope Trimer that Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Glycan-dependent HIV-specific neutralizing antibodies bind to cells of uninfected individuals

Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

HIV Immunology Goes Out On a Limb

HIV neutralizing antibodies: clinical correlates and implications for vaccines

HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

HIV-1 Gag p17 presented as virus-like particles on the E2 scaffold from Geobacillus stearothermophilus induces sustained humoral and cellular immune responses in the absence of IFNγ production by CD4+ T cells.

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins ⬇️

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

HIV-1 gp120-CD4-Induced Antibody Complex Elicits CD4 Binding Site-Specific Antibody Response in Mice

HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Isolation of human monoclonal antibodies from peripheral blood B cells

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Limited anti-HIV neutralizing antibody breadth and potency before and after HIV superinfection in Danish men who have sex with men

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

Multigene DNA prime-boost vaccines for SHIV89.6P

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies

Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness