Lista de obras -

(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents

artículo científico publicado en 2013

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

artículo científico publicado en 2017

CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking

artículo científico publicado en 2013

Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain

artículo científico publicado en 2014

Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lac

artículo científico publicado en 2014

Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.

artículo científico publicado en 2015

Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties

artículo científico publicado en 2013

Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.

artículo científico publicado en 2017

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

artículo científico publicado en 2016

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

artículo científico publicado en 2017

Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation

artículo científico publicado en 2012

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

scientific article published on 01 October 2018

Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides

artículo científico publicado en 2012

Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics

artículo científico publicado en 2019

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

artículo científico publicado en 2018

Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1.

artículo científico publicado en 2016

Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels

artículo científico publicado en 2014

The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents

artículo científico publicado en 2020

Lista de obras de

(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking

Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain

Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lac

Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.

Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties

Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides

Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1.

Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels

The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents