Lista de obras -

A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component

artículo científico publicado en 2014

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

artículo científico publicado en 2016

Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses

scientific article published on 25 July 2019

Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heterolo

artículo científico publicado en 2006

B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.

artículo científico publicado en 2018

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

artículo científico publicado en 2011

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

artículo científico publicado en 2012

Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus ⬇️

artículo científico publicado el 12 de septiembre de 2012

Changes in the immunogenic properties of soluble gp140 human immunodeficiency virus envelope constructs upon partial deletion of the second hypervariable region

artículo científico publicado en 2003

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

artículo científico publicado en 2011

Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses

artículo científico publicado en 2008

Comparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopes

artículo científico publicado en 2009

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

artículo científico publicado en 2010

Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1.

artículo científico publicado en 2011

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

article

Correction: Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs.

artículo científico publicado en 2013

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

artículo científico publicado en 2011

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

artículo científico publicado en 2017

Designed proteins assemble antibodies into modular nanocages

scientific article published on 01 December 2020

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

scientific article published on 25 July 2019

Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors

artículo científico publicado en 2016

Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection

artículo científico publicado en 2014

Emergence of broadly neutralizing antibodies and viral coevolution in two subjects during the early stages of infection with human immunodeficiency virus type 1

artículo científico publicado en 2014

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

artículo científico publicado en 2013

Engineering, Expression, Purification, and Characterization of Stable Clade A/B Recombinant Soluble Heterotrimeric gp140 Proteins ⬇️

artículo científico publicado el 26 de octubre de 2011

Epitope specificities of broadly neutralizing plasmas from HIV-1 infected subjects

artículo científico publicado en 2010

Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject

artículo científico publicado en 2012

Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection.

artículo científico publicado en 2009

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

artículo científico publicado en 2008

Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks

artículo científico publicado en 2014

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

artículo científico publicado en 2014

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

article

HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA

artículo científico publicado en 2011

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

scientific article published on 11 April 2019

Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

artículo científico publicado en 2005

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

artículo científico publicado en 2015

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

artículo científico publicado en 2011

Increased level and longevity of protective immune responses induced by DNA vaccine expressing the HIV-1 Env glycoprotein when combined with IL-21 and IL-15 gene delivery

artículo científico publicado en 2006

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

artículo científico publicado en 2016

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

artículo científico publicado en 2010

Isolation and characterization of monoclonal antibodies elicited by trimeric HIV-1 Env gp140 protein immunogens

artículo científico publicado en 2007

Macaques infected with a CCR5-tropic simian/human immunodeficiency virus (SHIV) develop broadly reactive anti-HIV neutralizing antibodies

artículo científico publicado en 2007

Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses

artículo científico publicado en 2014

Motif-optimized subtype A HIV envelope-based DNA vaccines rapidly elicit neutralizing antibodies when delivered sequentially

artículo científico publicado en 2012

N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

artículo científico publicado en 2004

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

artículo científico publicado en 2014

Prospects of HIV Env modification as an approach to HIV vaccine design

artículo científico publicado en 2007

Purification and characterization of oligomeric envelope glycoprotein from a primary R5 subtype B human immunodeficiency virus

artículo científico publicado en 2002

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

artículo científico publicado en 2013

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

artículo científico publicado en 2013

Repertoire comparison of the B-cell receptor-encoding loci in humans and rhesus macaques by next-generation sequencing

artículo científico publicado en 2016

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

artículo científico publicado en 2005

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

artículo científico publicado en 2013

Role of neutralizing antibodies in HIV infection

artículo científico publicado en 2003

Sequential immunization with a subtype B HIV-1 envelope quasispecies partially mimics the in vivo development of neutralizing antibodies

artículo científico publicado en 2011

Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation ⬇️

artículo científico publicado el 25 de julio de 2012

Soluble HIV-1 envelope immunogens derived from an elite neutralizer elicit cross-reactive V1V2 antibodies and low potency neutralizing antibodies

scientific article published on 23 January 2014

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

artículo científico publicado en 2016

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural basis for germline antibody recognition of HIV-1 immunogens

artículo científico publicado en 2016

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

artículo científico publicado en 2022

The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner

artículo científico publicado en 2005

Lista de obras de

A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses

Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heterolo

B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus ⬇️

Changes in the immunogenic properties of soluble gp140 human immunodeficiency virus envelope constructs upon partial deletion of the second hypervariable region

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses

Comparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopes

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

Correction: Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1.

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

Correction: Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs.

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

Designed proteins assemble antibodies into modular nanocages

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors

Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection

Emergence of broadly neutralizing antibodies and viral coevolution in two subjects during the early stages of infection with human immunodeficiency virus type 1

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

Engineering, Expression, Purification, and Characterization of Stable Clade A/B Recombinant Soluble Heterotrimeric gp140 Proteins ⬇️

Epitope specificities of broadly neutralizing plasmas from HIV-1 infected subjects

Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject

Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection.

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies

Increased level and longevity of protective immune responses induced by DNA vaccine expressing the HIV-1 Env glycoprotein when combined with IL-21 and IL-15 gene delivery

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

Isolation and characterization of monoclonal antibodies elicited by trimeric HIV-1 Env gp140 protein immunogens

Macaques infected with a CCR5-tropic simian/human immunodeficiency virus (SHIV) develop broadly reactive anti-HIV neutralizing antibodies

Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses

Motif-optimized subtype A HIV envelope-based DNA vaccines rapidly elicit neutralizing antibodies when delivered sequentially

N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

Prospects of HIV Env modification as an approach to HIV vaccine design

Purification and characterization of oligomeric envelope glycoprotein from a primary R5 subtype B human immunodeficiency virus

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

Repertoire comparison of the B-cell receptor-encoding loci in humans and rhesus macaques by next-generation sequencing

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

Role of neutralizing antibodies in HIV infection

Sequential immunization with a subtype B HIV-1 envelope quasispecies partially mimics the in vivo development of neutralizing antibodies

Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation ⬇️

Soluble HIV-1 envelope immunogens derived from an elite neutralizer elicit cross-reactive V1V2 antibodies and low potency neutralizing antibodies

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Structural basis for germline antibody recognition of HIV-1 immunogens

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner