Lista de obras -

A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis

artículo científico publicado en 2020

An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera

scientific article published on 04 September 2019

Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases

scientific article published on 24 February 2020

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes

artículo científico publicado en 2022

Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68

artículo científico publicado en 2019

D-alanine-D-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations

scientific article published on 25 April 2020

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex ⬇️

artículo científico publicado el 10 de abril de 2011

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

artículo científico publicado en 2022

Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme

artículo científico publicado en 2023

Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation

artículo científico publicado en 2022

Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

artículo científico publicado en 2022

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

scientific article published on 13 November 2019

Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase

artículo científico publicado en 2020

Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase

artículo científico publicado en 2018

Rational Design of a 310 -Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp

artículo científico publicado en 2018

Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid

artículo científico publicado en 2021

Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from Mycobacterium marinum

artículo científico publicado en 2018

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

artículo científico publicado en 2020

Structure of the Mycobacterium tuberculosis d -Alanine: d -Alanine Ligase, a Target of the Antituberculosis Drug d -Cycloserine ⬇️

artículo científico publicado el 18 de octubre de 2010

Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21.

artículo científico publicado en 2017

Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics

artículo científico

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads

artículo científico publicado en 2019

Targeting PCNA with Peptide Mimetics for Therapeutic Purposes

scientific article published on 15 October 2019

The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum

scientific article published on 28 February 2019

The role of N-terminal heterocycles in hydrogen bonding to α-chymotrypsin

scientific article published on 14 December 2018

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

scientific article published on 15 April 2019

Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA

artículo científico publicado en 2021

Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations

artículo científico publicado en 2021

Lista de obras de

A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis

An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera

Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases

Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes

Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68

D-alanine-D-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex ⬇️

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme

Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation

Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase

Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase

Rational Design of a 310 -Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp

Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid

Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from Mycobacterium marinum

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

Structure of the Mycobacterium tuberculosis d -Alanine: d -Alanine Ligase, a Target of the Antituberculosis Drug d -Cycloserine ⬇️

Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21.

Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads

Targeting PCNA with Peptide Mimetics for Therapeutic Purposes

The characterisation of two members of the cytochrome P450 CYP150 family: CYP150A5 and CYP150A6 from Mycobacterium marinum

The role of N-terminal heterocycles in hydrogen bonding to α-chymotrypsin

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA

Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations