Filtros de búsqueda

Lista de obras de

68Ga-DOTATATE PET/CT in the Localization of Head and Neck Paragangliomas Compared with Other Functional Imaging Modalities and CT/MRI

artículo científico publicado en 2015

A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days.

artículo científico publicado en 2005

A Phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar).

artículo científico publicado en 2001

A Phase II Multi-Center Study of Bevacizumab in Combination with Ixabepilone in Subjects with Advanced Renal Cell Carcinoma

artículo científico publicado en 2017

A Serial Analysis of Gene Expression (SAGE) database analysis of chemosensitivity: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins.

artículo científico publicado en 2004

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

artículo científico publicado en 2000

A database study that identifies genes whose expression correlates, negatively or positively, with 5-year survival of cancer patients

artículo científico publicado en 2007

A novel approach to assess real-world efficacy of cancer therapy in metastatic prostate cancer. Analysis of national data on Veterans treated with abiraterone and enzalutamide

scientific article published on 01 August 2019

A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy.

artículo científico publicado en 2008

A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer.

artículo científico publicado en 2010

A pharmacodynamic study of the P-glycoprotein antagonist CBT-1® in combination with paclitaxel in solid tumors.

artículo científico publicado en 2012

A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine

artículo científico publicado en 2009

A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma

artículo científico publicado en 2004

A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma

artículo científico publicado en 2010

A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine, and etoposide with daily mitotane as a P-glycoprotein antagonist.

artículo científico publicado en 2002

ANG1005 for breast cancer brain metastases: correlation between 18F-FLT-PET after first cycle and MRI in response assessment.

artículo científico publicado en 2016

Aberrant transcription from an unrelated promoter can result in MDR-1 expression following drug selection in vitro and in relapsed lymphoma samples

artículo científico publicado en 2005

Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism.

artículo científico publicado en 2001

Acetyl-L-carnitine and prevention of chemotherapy-induced peripheral neuropathy: can anything work?

artículo científico publicado en 2013

Adenovirus HSV-TK construct with thyroid-specific promoter: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the camp pathway

artículo científico publicado en 2002

Adjuvant and neoadjuvant cancer therapies: A historical review and a rational approach to understand outcomes

scientific article published on 26 January 2019

Adjuvant mitotane for adrenocortical cancer--a recurring controversy

artículo científico publicado en 2008

Adrenocortical Cancer: A Molecularly Complex Disease Where Surgery Matters

artículo científico publicado en 2016

Alu-associated interstitial deletions and chromosomal re-arrangement in 2 human multidrug-resistant cell lines

artículo científico publicado en 2000

Amplification of DNA sequences in human multidrug-resistant KB carcinoma cells

artículo científico publicado en 1985

An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain

artículo científico publicado en 2001

An Appraisal of Clinically Meaningful Outcomes Guidelines for Oncology Clinical Trials

artículo científico publicado en 2016

An information-intensive approach to the molecular pharmacology of cancer.

artículo científico publicado en 1997

Analyzing the pivotal trial that compared sunitinib and IFN-α in renal cell carcinoma, using a method that assesses tumor regression and growth.

artículo científico publicado en 2012

Anti-Hu paraneoplastic brainstem encephalitis caused by a pancreatic neuroendocrine tumor presenting with central hypoventilation.

artículo científico publicado en 2017

Are patients with hormonally functional phaeochromocytoma and paraganglioma initially receiving a proper adrenoceptor blockade? A retrospective cohort study

artículo científico publicado en 2016

Arsenic trioxide (As(2)O(3)): still a mystery

artículo científico publicado en 2002

Assessing the Eventual Publication of Clinical Trial Abstracts Submitted to a Large Annual Oncology Meeting

artículo científico publicado en 2016

BEZ235: When Promising Science Meets Clinical Reality

artículo científico publicado en 2016

Bevacizumab and breast cancer: the E2100 outlier

artículo científico publicado en 2010

Bevacizumab reduces the growth rate constants of renal carcinomas: a novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage

artículo científico publicado en 2008

Biologically targeted cancer therapy and marginal benefits: are we making too much of too little or are we achieving too little by giving too much?

artículo científico publicado en 2010

Brain metastasis in patients with adrenocortical carcinoma: a clinical series

artículo científico publicado en 2014

Breast implant-associated anaplastic large cell lymphoma in a patient with Li-Fraumeni syndrome

artículo científico publicado en 2015

CDK4/6 Inhibition as a therapeutic strategy in breast cancer: palbociclib, ribociclib, and abemaciclib

artículo científico publicado en 2017

CHARACTERISTICS AND OUTCOMES OF METASTATIC SDHB AND SPORADIC PHEOCHROMOCYTOMA/PARAGANGLIOMA: AN NATIONAL INSTITUTES OF HEALTH STUDY.

artículo científico publicado en 2015

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

artículo científico publicado en 1999

Can mutations in gamma-actin modulate the toxicity of microtubule targeting agents?

artículo científico publicado en 2006

Cancer drugs in the United States: Justum Pretium--the just price ⬇️

artículo científico publicado en 2013

Cancer therapies and the problem of me too many

artículo científico publicado en 2017

Cardiac studies in patients treated with depsipeptide, FK228, in a phase II trial for T-cell lymphoma

artículo científico publicado en 2006

Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.

artículo científico publicado en 2004

Challenges of evaluating the cardiac effects of anticancer agents

artículo científico publicado en 2006

Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein

artículo científico publicado en 1990

Characterization of gene rearrangements leading to activation of MDR-1.

artículo científico publicado en 2006

Cisplatin Every 3 Weeks Versus Weekly With Definitive Concurrent Radiotherapy for Squamous Cell Carcinoma of the Head and Neck

scientific article published on 01 May 2019

Cisplatin versus cetuximab with definitive concurrent radiotherapy for head and neck squamous cell carcinoma: An analysis of veterans health affairs data

article

Clinical Reversal of Multidrug Resistance

artículo científico publicado en 1996

Clinical reversal of multidrug resistance

artículo científico publicado en 1996

Clinical trial results: Sharing results, speeding discoveries

artículo científico publicado en 2013

Clinical trial results: a clinical trial bazaar!

artículo científico publicado en 2014

Clinical trials: New drug for pancreatic cancer highlights the dual effect of regulatory approvals

artículo científico publicado en 2016

Colorectal Cancer Survival Gains and Novel Treatment Regimens: A Systematic Review and Analysis

artículo científico

Combination chemotherapy in advanced adrenocortical carcinoma

artículo científico publicado en 2012

Combinations of paclitaxel and vinblastine and their effects on tubulin polymerization and cellular cytotoxicity: characterization of a synergistic schedule

artículo científico publicado en 1998

Commentary: Novel therapies for cancer: why dirty might be better

artículo científico publicado en 2008

Comparison by Race of Conservative Management for Low-Risk and Intermediate-Risk Prostate Cancers in Veterans From 2004 to 2018

scientific article published on 01 September 2020

Complementation of two mutant p53: implications for loss of heterozygosity in cancer

artículo científico publicado en 2005

Conservation of the class I beta-tubulin gene in human populations and lack of mutations in lung cancers and paclitaxel-resistant ovarian cancers.

artículo científico publicado en 2002

Continued Tumor Reduction of Metastatic Pheochromocytoma/Paraganglioma Harboring Succinate Dehydrogenase Subunit B Mutations with Cyclical Chemotherapy.

artículo científico publicado en 2018

Continuing a cancer treatment despite tumor growth may be valuable: sunitinib in renal cell carcinoma as example

artículo científico publicado en 2014

Contribution of glutathione and glutathione-dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines ⬇️

artículo científico publicado el 11 de noviembre de 1991

Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy ⬇️

artículo científico publicado el 1 de agosto de 1995

Correction: Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using Cu-plerixafor PET

Cuba Sí. Cancer No

artículo científico publicado en 2018

Current approaches and recent developments in the management of head and neck paragangliomas

artículo científico publicado en 2014

Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.

artículo científico

Decade in review-funding in cancer research: National Cancer Institute awards-a work in progress

artículo científico publicado en 2014

Delivering affordable cancer care in high-income countries

article

Depletion of mutant p53 and cytotoxicity of histone deacetylase inhibitors

artículo científico publicado en 2005

Design of placebo-controlled randomized trials of anticancer agents: Ethical considerations based on a review of published trials

artículo científico publicado en 2021

Desperation Oncology

artículo científico publicado en 2018

Differential expression of cell adhesion genes: implications for drug resistance

artículo científico publicado en 2005

Differential modulation of P-glycoprotein transport by protein kinase inhibition ⬇️

artículo científico publicado el 7 de septiembre de 1993

Distribution of cancer genes in human chromosomes

scientific article published on 19 June 2020

Do patient access schemes for high-cost cancer drugs deliver value to society?-lessons from the NHS Cancer Drugs Fund

artículo científico publicado en 2017

Drug resistance in adult lymphomas

artículo científico publicado en 1994

EPOCH chemotherapy: toxicity and efficacy in relapsed and refractory non-Hodgkin's lymphoma ⬇️

artículo científico publicado el 1 de agosto de 1993

Editor's Note …Clinical Trial Reports: A New Section ⬇️

artículo científico publicado el 1 de enero de 2012

Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

scientific article published on 01 January 1999

Emerging Therapeutic Implications of STK11 Mutation: Case Series

scientific article published on 12 May 2020

Enhanced detection of treatment effects on metastatic colorectal cancer with volumetric CT measurements for tumor burden growth rate evaluation

artículo científico publicado en 2020

Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics

artículo científico publicado en 2002

Enhancement of aqueous solubility and stability employing a trans acetate axis in trans planar amine platinum compounds while maintaining the biological profile

artículo científico publicado en 2005

Epidemiologic trends in neuroendocrine tumors: An examination of incidence rates and survival of specific patient subgroups over the past 20 years

artículo científico publicado en 2018

Epidermal growth factor receptor inhibitors: a moving target?

artículo científico publicado en 2005

Epothilones: a novel class of non-taxane microtubule-stabilizing agents

artículo científico publicado en 2002

Estimation of tumour regression and growth rates during treatment in patients with advanced prostate cancer: a retrospective analysis

artículo científico publicado en 2016

Evidence for microtubule target engagement in tumors of patients receiving ixabepilone

artículo científico publicado en 2007

Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection

artículo científico publicado en 2008

Expression of ATP binding cassette superfamily (multidrug resistance-1, multidrug resistance-associated protein, human canalicular multispecific organ anion transporter) mRNA in etoposide and m-AMSA resistant cell lines

artículo científico publicado el 1 de octubre de 1997

Expression of DNA topoisomerases (I, II alpha, II beta) mRNA in etoposide- and mAMSA-resistant cell lines

artículo científico publicado el 1 de diciembre de 1997

Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation

artículo científico publicado en 1989

Expression of a multidrug resistance gene in human cancers

artículo científico publicado en 1989

Expression of a multidrug-resistance gene in human tumors and tissues

artículo científico publicado en 1987

Expression of drug resistance genes in VP-16 and mAMSA-selected human carcinoma cells

artículo científico publicado en 2001

Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia.

artículo científico publicado en 1989

Expression of the multidrug resistance, MDR1, gene in neuroblastomas

artículo científico publicado en 1990

Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay

artículo científico publicado en 1997

Expression of the multidrug-resistant gene in hepatocarcinogenesis and regenerating rat liver.

artículo científico publicado en 1987

External beam radiation therapy in treatment of malignant pheochromocytoma and paraganglioma

artículo científico publicado en 2014

False-negative 123I-MIBG SPECT is most commonly found in SDHB-related pheochromocytoma or paraganglioma with high frequency to develop metastatic disease ⬇️

artículo científico publicado el 13 de febrero de 2012

Female fertility following dose-adjusted EPOCH-R chemotherapy in primary mediastinal B-cell lymphomas

artículo científico publicado en 2016

From the guest editor: monitoring of therapeutic response to cancer treatment

scientific article published on 01 September 2009

Functional Imaging Signature of Patients Presenting with Polycythemia/Paraganglioma Syndromes

artículo científico publicado en 2017

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials.

artículo científico publicado en 2015

Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line

artículo científico publicado en 2005

HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

artículo científico publicado en 2003

Hazard ratios in cancer clinical trials--a primer.

artículo científico publicado en 2012

High-Dose Sirolimus and Immune-Selective Pentostatin plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-versus-Tumor Responses

artículo científico publicado en 2015

Histone deacetylase inhibitor FR901228 enhances adenovirus infection of hematopoietic cells

artículo científico publicado en 2002

Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.

artículo científico publicado en 2002

How much is life worth: cetuximab, non-small cell lung cancer, and the $440 billion question

artículo científico publicado en 2009

Hypophosphorylation of topoisomerase IIalpha in etoposide (VP-16)-resistant human carcinoma cell lines associated with carboxy-terminal truncation

artículo científico publicado en 2001

Identification of Non-Small Cell Lung Cancer Sensitive to Systemic Cancer Therapies Using Radiomics

artículo científico publicado en 2020

Identification of mutations at DNA topoisomerase I responsible for camptothecin resistance.

artículo científico publicado en 1997

Identification of non-cross-resistant platinum compounds with novel cytotoxicity profiles using the NCI anticancer drug screen and clustered image map visualizations

artículo científico publicado en 2005

Immunotherapy for adrenocortical cancer

scientific article published on 01 February 2019

Impaired p53 binding to importin: a novel mechanism of cytoplasmic sequestration identified in oxaliplatin-resistant cells

artículo científico publicado en 2009

Incidence of mutation and deletion in topoisomerase II alpha mRNA of etoposide and mAMSA-resistant cell lines

artículo científico publicado en 2001

Increased 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576.

artículo científico publicado en 2003

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines

artículo científico publicado en 1988

Increased MDR1 expression in normal and malignant peripheral blood mononuclear cells obtained from patients receiving depsipeptide (FR901228, FK228, NSC630176).

artículo científico publicado en 2006

Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists.

artículo científico publicado en 1993

Increased uptake of [¹²³I]meta-iodobenzylguanidine, [¹⁸F]fluorodopamine, and [³H]norepinephrine in mouse pheochromocytoma cells and tumors after treatment with the histone deacetylase inhibitors

artículo científico publicado en 2011

Influence of Cancer on COVID-19 Incidence, Outcomes, and Vaccine Effectiveness: A Prospective Cohort Study of U.S. Veterans

artículo científico publicado en 2022

Inhibiting mitochondrial respiration prevents cancer in a mouse model of Li-Fraumeni syndrome

artículo científico publicado en 2016

Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).

artículo científico publicado en 2007

Inhibition of transcription results in accumulation of Wt p53 followed by delayed outburst of p53-inducible proteins: p53 as a sensor of transcriptional integrity.

artículo científico publicado en 2002

Inhibitors Targeting Mitosis: Tales of How Great Drugs against a Promising Target Were Brought Down by a Flawed Rationale ⬇️

artículo científico publicado el 1 de enero de 2012

Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist

artículo científico publicado en 1997

Interleukin-13 receptor alpha2 is a novel therapeutic target for human adrenocortical carcinoma

artículo científico publicado en 2012

Intrinsic drug resistance in human kidney cancer is associated with expression of a human multidrug-resistance gene.

artículo científico publicado en 1987

Introduction: chemotherapies in the treatment of breast cancer

artículo científico publicado en 2005

Is cell death a critical end point for anticancer therapies or is cytostasis sufficient?

artículo científico publicado en 2007

Is there room for improvement in adverse event reporting in the era of targeted therapies?

scientific article published on 12 February 2008

Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

artículo científico publicado en 1985

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

artículo científico publicado en 1986

Laboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma

artículo científico publicado en 2009

Liver resection and ablation for metastatic adrenocortical carcinoma

artículo científico publicado en 2011

Localization of multidrug resistance-associated DNA sequences to human chromosome 7.

artículo científico publicado en 1986

Long-acting somatostatin analogues in the treatment of unresectable/metastatic neuroendocrine tumors

artículo científico publicado en 2017

Management of endocrine manifestations and the use of mitotane as a chemotherapeutic agent for adrenocortical carcinoma

scientific article published on 10 August 2009

Mechanisms of resistance to PARP inhibitors--three and counting.

artículo científico publicado en 2013

Mechanisms of resistance to cisplatin and alkylating agents.

artículo científico

Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior

artículo científico publicado en 2008

Metallothionein gene expression and resistance to cisplatin in human ovarian cancer

artículo científico publicado en 1990

Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape

artículo científico publicado en 2020

Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence: significant link to SDHB mutations

artículo científico publicado en 2011

Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations

artículo científico publicado en 1996

MiR-34a and miR-483-5p are candidate serum biomarkers for adrenocortical tumors

artículo científico publicado en 2013

MicroRNA profiling of adrenocortical tumors reveals miR‐483 as a marker of malignancy ⬇️

artículo científico publicado el 8 de noviembre de 2010

Microtubule targeting agents: basic mechanisms of multidrug resistance (MDR).

artículo científico publicado en 2005

Microtubule-disrupting chemotherapeutics result in enhanced proteasome-mediated degradation and disappearance of tubulin in neural cells

artículo científico publicado en 2010

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

artículo científico publicado en 1998

Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins

artículo científico publicado en 2015

Mitosis is not a key target of microtubule agents in patient tumors.

artículo científico publicado en 2011

Mitotane Enhances Cytotoxicity of Chemotherapy in Cell Lines Expressing a Multidrug Resistance Gene (mdr-1/P-Glycoprotein) which is also Expressed by Adrenocortical Carcinomas ⬇️

artículo científico publicado el 1 de julio de 1991

Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

artículo científico publicado el 21 de julio de 1992

Modulation of multidrug resistance by dexverapamil in EPOCH-refractory lymphomas.

artículo científico publicado en 1995

Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents.

artículo científico publicado en 1989

Molecular biology of drug resistance

artículo científico publicado en 1987

Molecular effects of paclitaxel: myths and reality (a critical review).

artículo científico publicado en 1999

Molecular targets in the National Cancer Institute drug screen

artículo científico publicado en 1995

Moving a pioneer journal into the future

artículo científico publicado en 2016

Multidrug resistance in cancer: role of ATP-dependent transporters

artículo científico publicado en 2002

Multidrug resistance in ovarian cancer

artículo científico publicado en 1987

Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene

artículo científico publicado en 1986

Multidrug resistance: P-glycoprotein and its allies--the elusive foes.

artículo científico publicado en 1989

Multiple paths to a drug resistance phenotype: mutations, translocations, deletions and amplification of coding genes or promoter regions, epigenetic changes and microRNAs

artículo científico publicado en 2007

Multiplying therapies and reducing toxicity in metastatic melanoma

artículo científico publicado en 2015

Neutral evolution of drug resistant colorectal cancer cell populations is independent of their KRAS status.

artículo científico publicado en 2017

New syndrome of paraganglioma and somatostatinoma associated with polycythemia

artículo científico publicado en 2013

Non-inferiority trials: why oncologists must remain wary

artículo científico publicado en 2015

Novel Tumor Growth Rate Analysis in the Randomized CLARINET Study Establishes the Efficacy of Lanreotide Depot/Autogel 120 mg With Prolonged Administration in Indolent Neuroendocrine Tumors

scientific article published on 03 January 2021

Novel insights into the polycythemia-paraganglioma-somatostatinoma syndrome

artículo científico publicado en 2016

Oligomerization of p53 precedes its association with dynein and nuclear accumulation

artículo científico publicado en 2006

Operative management for recurrent and metastatic adrenocortical carcinoma

artículo científico publicado en 2011

Oral anticancer drugs: how limited dosing options and dose reductions may affect outcomes in comparative trials and efficacy in patients

artículo científico publicado en 2014

P-glycoprotein expression and schedule dependence of adriamycin cytotoxicity in human colon carcinoma cell lines

artículo científico publicado en 1991

PET/CT comparing (68)Ga-DOTATATE and other radiopharmaceuticals and in comparison with CT/MRI for the localization of sporadic metastatic pheochromocytoma and paraganglioma

artículo científico publicado en 2016

Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion.

artículo científico publicado en 1994

Paclitaxel-induced FasL-independent apoptosis and slow (non-apoptotic) cell death.

artículo científico publicado en 2002

Pancreatic cancer: Targeting KRAS and the vitamin D receptor via microtubules

artículo científico publicado en 2015

Percutaneous tumor ablation with radiofrequency

artículo científico publicado en 2002

Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma

artículo científico publicado en 2011

Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833.

artículo científico publicado en 2001

Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.

artículo científico publicado en 2003

Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors

artículo científico publicado en 2008

Phase I trial of a new schedule of romidepsin in patients with advanced cancers

artículo científico publicado en 2013

Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung.

artículo científico publicado en 2018

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

artículo científico publicado en 2002

Phase I/II Trial of Vandetanib and Bortezomib in Adults with Locally Advanced or Metastatic Medullary Thyroid Cancer

article

Phase II Clinical Trial of Ixabepilone in Metastatic Cervical Carcinoma

artículo científico publicado en 2015

Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer

artículo científico publicado en 2005

Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma

artículo científico publicado en 2009

Phase II study of paclitaxel in relapsed non-Hodgkin's lymphomas

scientific article published on 01 February 1995

Potential Pitfalls of Crossover and Thoughts on Iniparib in Triple-Negative Breast Cancer ⬇️

artículo científico publicado el 7 de diciembre de 2011

Practical considerations in the evaluation and management of adrenocortical cancer

artículo científico publicado en 2010

Precision oncology: a strategy we were not ready to deploy

artículo científico publicado en 2016

Precision oncology: origins, optimism, and potential

artículo científico publicado en 2016

Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs

artículo científico publicado en 2000

Price, value, and the cost of cancer drugs

artículo científico publicado en 2015

Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models

artículo científico publicado en 2019

Progression-free survival is simply a measure of a drug's effect while administered and is not a surrogate for overall survival.

artículo científico publicado en 2009

Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: a possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition.

artículo científico publicado en 2008

Pseudo-progressing to an unmet need.

artículo científico publicado en 2017

Pulmonary Resection for Metastatic Adrenocortical Carcinoma: The National Cancer Institute Experience ⬇️

artículo científico publicado el 1 de octubre de 2011

RECIST: no longer the sharpest tool in the oncology clinical trials toolbox--reply to point

Radiofrequency ablation for tumor-related massive hematuria

artículo científico publicado en 2005

Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastases

artículo científico publicado en 2003

Radiofrequency ablation of metastatic lesions in adrenocortical cancer

artículo científico publicado en 2000

Radiofrequency ablation of metastatic pheochromocytoma

artículo científico publicado en 2009

Radiofrequency ablation: a novel approach for treatment of metastatic pheochromocytoma

artículo científico publicado en 2001

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

artículo científico publicado en 2014

Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines.

artículo científico publicado en 1985

Renal cell carcinoma: trying but failing to improve the only curative therapy

artículo científico publicado en 2013

Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'

scientific article published on 01 October 2019

Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin.

artículo científico publicado en 2012

Reversal of Multidrug Resistance

artículo científico publicado en 1994

Reversal of multidrug resistance.

artículo científico publicado en 1994

Reversal of multidrug resistance: lessons from clinical oncology.

artículo científico publicado en 2002

Revisiting the role of ABC transporters in multidrug-resistant cancer.

artículo científico publicado en 2018

Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.

artículo científico

Role of a doxorubicin-containing regimen in relapsed and resistant lymphomas: an 8-year follow-up study of EPOCH.

artículo científico publicado en 2000

Role of radiotherapy in adrenocortical carcinoma

artículo científico publicado en 2013

Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

artículo científico publicado en 2015

SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations

artículo científico publicado en 2017

Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using 64Cu-plerixafor PET.

artículo científico publicado en 2017

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

artículo científico publicado en 2012

Sorafenib-induced eruptive melanocytic lesions.

artículo científico publicado en 2008

Stable disease is not preferentially observed with targeted therapies and as currently defined has limited value in drug development.

artículo científico publicado en 2009

Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells

artículo científico publicado en 1996

Strategies for reversing drug resistance ⬇️

artículo científico publicado el 20 de octubre de 2003

Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma

artículo científico publicado en 2009

Succinate dehydrogenase gene mutations in cardiac paragangliomas

artículo científico publicado en 2015

Sunitinib Does Not Accelerate Tumor Growth in Patients with Metastatic Renal Cell Carcinoma

artículo científico publicado en 2013

Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma

artículo científico publicado en 2015

Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

artículo científico publicado en 2001

TARP vaccination is associated with slowing in PSA velocity and decreasing tumor growth rates in patients with Stage D0 prostate cancer

artículo científico publicado en 2016

Taccalonolides: a microtubule stabilizer poses a new puzzle with old pieces

artículo científico publicado en 2011

Tales of how great drugs were brought down by a flawed rationale--response

artículo científico publicado en 2013

Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies.

artículo científico publicado en 2012

The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel.

artículo científico publicado en 2001

The Role of ABC Transporters in Clinical Practice ⬇️

artículo científico publicado el 1 de enero de 2003

The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of Platinum Resistance with a Chk2 Inhibitor ⬇️

artículo científico publicado el 1 de enero de 2011

The VEGF inhibitor axitinib has limited effectiveness as a therapy for adrenocortical cancer

artículo científico publicado en 2014

The clinical development of new mitotic inhibitors that stabilize the microtubule

artículo científico publicado en 2004

The evidence framework for precision cancer medicine

artículo científico publicado en 2017

The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration

artículo científico

The high cost of ignorance in oncology.

artículo científico publicado en 2016

The histone deacetylase inhibitor FK228 given prior to adenovirus infection can boost infection in melanoma xenograft model systems

artículo científico publicado en 2007

The histone deacetylase inhibitor FK228 preferentially enhances adenovirus transgene expression in malignant cells ⬇️

artículo científico publicado el 1 de noviembre de 2003

The histone deacetylase inhibitor FR901228 (desipeptide) restores expression and function of pseudo-null p53.

artículo científico publicado en 2002

The role of efflux pumps in drug-resistant metastatic breast cancer: new insights and treatment strategies

artículo científico publicado en 2007

The size of the primary tumor and age at initial diagnosis are independent predictors of the metastatic behavior and survival of patients with SDHB-related pheochromocytoma and paraganglioma: a retrospective cohort study

artículo científico publicado en 2014

Therapeutic Cancer Vaccines in Prostate Cancer: The Paradox of Improved Survival Without Changes in Time to Progression ⬇️

artículo científico publicado el 26 de agosto de 2010

Therapies with diverse mechanisms of action kill cells by a similar exponential process in advanced cancers.

artículo científico publicado en 2014

Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: recommendation from a 22-year follow-up of 18 patients

artículo científico publicado en 2008

Treatment of metastatic disease in patients with neuroendocrine tumors

artículo científico publicado en 2006

Treatment of recurrent cervical adenocarcinoma with BMS-247550, an epothilone B analog

artículo científico publicado en 2003

Tubulin from paclitaxel-resistant cells as a probe for novel antimicrotubule agents

artículo científico publicado en 1997

Tubulin/microtubules: still a promising target for new chemotherapeutic agents

artículo científico publicado en 2000

Tumor Regression and Growth Rates Determined in Five Intramural NCI Prostate Cancer Trials: The Growth Rate Constant as an Indicator of Therapeutic Efficacy ⬇️

artículo científico publicado el 24 de noviembre de 2010

Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability

artículo científico publicado en 2004

Tumor growth rates derived from data for patients in a clinical trial correlate strongly with patient survival: a novel strategy for evaluation of clinical trial data

artículo científico publicado en 2008

Tumour stem cells and drug resistance

artículo científico publicado en 2005

Unintended consequences of expensive cancer therapeutics—the pursuit of marginal indications and a me-too mentality that stifles innovation and creativity: the John Conley Lecture

artículo científico publicado en 2014

Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.

artículo científico publicado en 1990

Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles

artículo científico publicado en 1998

Various methods of analysis of mdr-1/P-glycoprotein in human colon cancer cell lines

artículo científico publicado el 6 de mayo de 1992

Why RECIST works and why it should stay--counterpoint

artículo científico

Why do phase III clinical trials in oncology fail so often?

artículo científico publicado en 2012

bcl-2 protein downregulation is not required for differentiation of multidrug resistant HL60 leukemia cells

artículo científico publicado en 1996

p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription ⬇️

artículo científico publicado el 15 de mayo de 1998

p53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53.

artículo científico publicado en 2002

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

scientific article published on 01 October 2000

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda