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4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells

artículo científico publicado en 2014

A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

artículo científico publicado en 2018

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

artículo científico

A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals

artículo científico publicado en 2012

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

scientific journal article

A module of negative feedback regulators defines growth factor signaling

artículo científico publicado en 2007

A negative feedback loop of transcription factors specifies alternative dendritic cell chromatin States.

artículo científico publicado en 2014

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

scientific article published on 25 April 2019

A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration

artículo científico publicado en 2007

A single cell atlas of the human liver tumor microenvironment

artículo científico publicado en 2020

Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function

artículo científico publicado en 2014

Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators

artículo científico publicado en 2014

Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

artículo científico publicado en 2018

Author Correction: Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

artículo científico publicado en 2020

Author Correction: Microglial immune checkpoint mechanisms

scientific article published on 01 August 2018

Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation

artículo científico publicado en 2017

Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment

artículo científico publicado en 2020

C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

artículo científico publicado en 2020

C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

scientific article published on 01 May 2020

CD74 is a novel transcription regulator

artículo científico publicado en 2016

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

artículo científico publicado en 2009

Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner

artículo científico publicado en 2014

Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution

artículo científico publicado en 2016

Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells

artículo científico publicado en 2011

Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

article

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

artículo científico publicado en 2009

Corrigendum: Derivation of novel human ground state naive pluripotent stem cells

scientific article published on 01 April 2015

Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency

scientific article published on 01 April 2015

Corrigendum: The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

artículo científico publicado en 2017

Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer

scientific article published on 04 August 2020

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

scientific article published on 01 December 2019

Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program

scientific article published on 01 April 2020

Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

scientific article published on 20 April 2020

DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node

artículo científico publicado en 2019

DCs are ready to commit

artículo científico publicado en 2015

Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

artículo científico publicado en 2013

Deciphering the state of immune silence in fatal COVID-19 patients

artículo científico publicado en 2021

Derivation of novel human ground state naive pluripotent stem cells

artículo científico publicado en 2013

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

scientific article published on 13 December 2018

Deterministic direct reprogramming of somatic cells to pluripotency

artículo científico publicado en 2013

Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

artículo científico publicado en 2017

Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

artículo científico publicado en 2018

Digital cell quantification identifies global immune cell dynamics during influenza infection

artículo científico publicado en 2014

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

artículo científico publicado en 2018

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

artículo científico publicado en 2016

Dissecting cellular crosstalk by sequencing physically interacting cells

scientific article published on 09 March 2020

Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing

artículo científico publicado en 2018

Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes.

artículo científico publicado en 2015

Distinct biological events generated by ECM proteolysis by two homologous collagenases

artículo científico publicado en 2016

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

scientific article published on 27 December 2018

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

scientific article published on 01 April 2020

EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

artículo científico publicado en 2010

EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.

artículo científico publicado en 2011

ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma

scientific article published on 01 October 2019

Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics

artículo científico publicado en 2015

Early metazoan cell type diversity and the evolution of multicellular gene regulation

article

Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19

scientific article published on 05 August 2020

Embrace the fat when getting old

scientific article published on 23 October 2019

Erratum: Single-cell spatial reconstruction reveals global division of labour in the mammalian liver.

artículo científico publicado en 2017

Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy

artículo científico publicado en 2007

Expression noise and acetylation profiles distinguish HDAC functions

artículo científico publicado en 2012

Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality.

artículo científico publicado en 2016

From mass cytometry to cancer prognosis

scientific article published on 01 September 2015

From the Human Cell Atlas to dynamic immune maps in human disease

artículo científico publicado en 2018

Full-length transcriptome assembly from RNA-Seq data without a reference genome

artículo científico publicado en 2011

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C- Cells.

artículo científico publicado en 2017

High-resolution chromatin dynamics during a yeast stress response

artículo científico publicado en 2015

High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies

artículo científico publicado en 2014

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

artículo científico publicado en 2013

Host microbiota constantly control maturation and function of microglia in the CNS.

artículo científico publicado en 2015

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

artículo científico publicado en 2020

Immunogenetics. Chromatin state dynamics during blood formation

artículo científico publicado en 2014

Immunology, one cell at a time

artículo científico publicado en 2017

Impaired immune surveillance accelerates accumulation of senescent cells and aging

artículo científico publicado en 2018

Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System

artículo científico publicado en 2020

Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.

artículo científico publicado en 2017

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

artículo científico publicado en 2004

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

scientific article published on 27 June 2019

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

artículo científico publicado en 2018

M(odu)LLating the innate response

scientific article published on 01 April 2012

M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration.

artículo científico publicado en 2015

Making the case for chromatin profiling: a new tool to investigate the immune-regulatory landscape.

artículo científico publicado en 2015

Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

artículo científico publicado en 2014

Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

scientific article published on 26 November 2019

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.

artículo científico publicado en 2017

Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies

artículo científico publicado en 2020

MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions

scientific article published on 11 October 2019

Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

artículo científico publicado en 2011

MicroRNA-142 controls thymocyte proliferation

artículo científico publicado en 2017

Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

artículo científico publicado en 2017

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

artículo científico publicado en 2016

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

artículo científico publicado en 2015

Microglia development follows a stepwise program to regulate brain homeostasis

artículo científico publicado en 2016

Microglial immune checkpoint mechanisms

artículo científico publicado en 2018

Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis

artículo científico publicado en 2012

NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis

scientific article published on 04 January 2021

Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia

artículo científico publicado en 2012

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease

artículo científico publicado en 2016

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

artículo científico publicado en 2019

Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

article

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

scientific article published on 18 June 2019

Plasticity in the transcriptional and epigenetic circuits regulating dendritic cell lineage specification and function.

artículo científico

Publisher Correction: Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation

artículo científico publicado en 2020

Regulation of MAPKs by growth factors and receptor tyrosine kinases

artículo científico publicado en 2007

Salient experiences are represented by unique transcriptional signatures in the mouse brain.

artículo científico publicado en 2018

Semiconductor-based DNA sequencing of histone modification states

artículo científico publicado en 2013

Sequential feedback induction stabilizes the phosphate starvation response in budding yeast.

artículo científico publicado en 2014

Simultaneous measurement of genome-wide transcription elongation speeds and rates of RNA polymerase II transition into active elongation with 4sUDRB-seq.

artículo científico publicado en 2015

Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma

artículo científico publicado en 2018

Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity

scientific article published on 13 February 2019

Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

artículo científico publicado en 2018

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

artículo científico publicado en 2018

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

artículo científico publicado en 2018

Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

artículo científico publicado en 2017

Single-cell transcriptome conservation in cryopreserved cells and tissues

artículo científico publicado en 2017

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq.

artículo científico publicado en 2017

Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells

artículo científico publicado en 2020

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

artículo científico publicado en 2015

Strategies to discover regulatory circuits of the mammalian immune system

artículo científico publicado en 2011

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

artículo científico publicado en 2015

Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling

artículo científico publicado en 2005

Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression

artículo científico publicado en 2017

Systematic discovery of TLR signaling components delineates viral-sensing circuits

artículo científico publicado en 2011

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

artículo científico publicado en 2017

Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding

artículo científico publicado en 2004

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

artículo científico publicado en 2012

The Human Cell Atlas

artículo científico publicado en 2017

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

artículo científico publicado en 2018

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

artículo científico publicado en 2020

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

artículo científico publicado en 2016

The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation.

artículo científico publicado en 2018

The phosphoproteome of toll-like receptor-activated macrophages

artículo científico publicado en 2010

The role of chromatin dynamics in immune cell development

artículo científico publicado en 2014

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis.

artículo científico

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

artículo científico publicado en 2014

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

scholarly article by Moriya Gamliel et al published May 2018 in Immunity

Transcription factor binding dynamics during human ES cell differentiation

artículo científico publicado en 2015

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

artículo científico publicado en 2015

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

artículo científico publicado en 2016

Transcriptional programs that control expression of the autoimmune regulator gene Aire

artículo científico publicado en 2016

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

artículo científico publicado en 2009

Voices of biotech

artículo científico publicado en 2016

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