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4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion

scientific article published on 01 April 2019

A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition

artículo científico publicado en 2019

A comprehensive analysis of breast cancer microbiota and host gene expression.

artículo científico publicado en 2017

A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303

scientific journal article

A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.

artículo científico publicado en 2015

ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

artículo científico publicado en 2019

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor α

artículo científico publicado en 2020

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics

artículo científico publicado en 2014

Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression

artículo científico publicado en 2012

Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.

artículo científico publicado en 2018

Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1

artículo científico publicado en 2020

BRCA1/2 Mutations and Bevacizumab in the Neoadjuvant Treatment of Breast Cancer: Response and Prognosis Results in Patients With Triple-Negative Breast Cancer From the GeparQuinto Study

article

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

artículo científico publicado en 2018

Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes

artículo científico publicado en 2017

Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms

artículo científico publicado en 2008

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

artículo científico publicado en 2017

CRM1 inhibitor anti-tumor activity is enhanced with salicylates by S-phase arrest and impaired DNA-damage repair

artículo científico publicado en 2020

Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion

artículo científico publicado en 2017

Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy

artículo científico publicado en 2016

Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol)

artículo científico publicado en 2020

Comparison of 99mTc-Sestamibi Molecular Breast Imaging and Breast MRI in Patients With Invasive Breast Cancer Receiving Neoadjuvant Chemotherapy

artículo científico publicado en 2019

Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics

artículo científico publicado en 2009

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

artículo científico publicado en 2018

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

scientific article published on 01 October 2019

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation

artículo científico publicado en 2018

Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer.

artículo científico publicado en 2018

Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity

artículo científico publicado en 2010

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

artículo científico publicado en 2017

Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation

artículo científico publicado en 2016

Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

artículo científico publicado en 2014

Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy

artículo científico publicado en 2015

FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder

artículo científico publicado en 2013

Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors

artículo científico publicado en 2010

Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy

artículo científico publicado en 2016

Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors

artículo científico publicado en 2010

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab

artículo científico publicado en 2018

HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data

scholarly article by Saurabh Baheti published in July 2018

Implementation of preemptive DNA sequence–based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study

artículo científico publicado en 2022

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression.

artículo científico publicado en 2018

MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication

artículo científico publicado en 2021

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

scientific article published on 04 September 2018

PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient

scientific article published on 01 December 2018

Pharmacogenomic Discovery to Function and Mechanism: Breast Cancer as a Case Study

artículo científico publicado en 2017

Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action

scientific article published on 23 July 2020

Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks

artículo científico publicado en 2021

Regulation of sister chromatid cohesion by nuclear PD-L1

artículo científico publicado en 2020

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

artículo científico publicado en 2017

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1

artículo científico publicado en 2017

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention

artículo científico publicado en 2013

Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer

artículo científico publicado en 2020

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall

artículo científico publicado en 2019

TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-κB Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune

scientific article published on 14 June 2017

TCL1A, a novel transcription factor and a co-regulator of NF-кB p65: SNP and estrogen-dependence

artículo científico publicado en 2018

TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression

artículo científico publicado en 2013

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer

article published in 2019

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

artículo científico publicado en 2017

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway

artículo científico publicado en 2018