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"Houston, we have a problem": "We are losing our eyesight"

scientific article published on 14 July 2019

"Hypodense Holes" and the Ocular Glymphatic System: Author Response: "Black Holes" and the Ocular Glymphatic System.

artículo científico publicado en 2017

A General Decline in Cerebrospinal Fluid Flow: An Overlooked Risk Factor for Glaucoma?

artículo científico publicado en 2016

A New Look at Glaucoma

artículo científico publicado en 2015

A general decline in cerebrospinal fluid flow and optic nerve compartmentation: are these sequential steps leading to toxicity in normal-tension glaucoma?

artículo científico publicado en 2016

A new glaucoma hypothesis: a role of glymphatic system dysfunction

artículo científico publicado en 2015

Age-related macular degeneration, glaucoma and Alzheimer's disease: amyloidogenic diseases with the same glymphatic background?

artículo científico publicado en 2016

Alzheimer's disease and glaucoma: Look-alike neurodegenerative diseases

artículo científico publicado en 2019

Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity?

artículo científico publicado en 2016

Alzheimer's disease-related changes in diseases characterized by elevation of intracranial or intraocular pressure

artículo científico publicado en 2007

Alzheimer's disease: cerebral glaucoma?

artículo científico publicado en 2010

An abnormal high trans-lamina cribrosa pressure difference: a missing link between Alzheimer's disease and glaucoma?

artículo científico publicado en 2008

Are intracranial pressure fluctuations important in glaucoma?

scientific article published on 20 July 2011

COVID-19 and chronic fatigue syndrome: Is the worst yet to come?

artículo científico publicado en 2021

Can cerebrospinal fluid diversion be beneficial in the treatment of chronic fatigue syndrome?

artículo científico publicado en 2018

Choroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer's Disease Therapy

artículo científico publicado en 2011

Choroidal thickness changes in astronauts during and after spaceflight

artículo científico publicado en 2020

Dilated Prelaminar Paravascular Spaces as a Possible Mechanism for Optic Disc Edema in Astronauts

scientific article published on 01 December 2018

Dilated Virchow-Robin spaces in primary open-angle glaucoma: a biomarker of glymphatic waste clearance dysfunction?

artículo científico publicado en 2016

Do normal-tension and high-tension glaucoma result from brain and ocular glymphatic system disturbances, respectively?

artículo científico publicado en 2020

Do repetitive Valsalva maneuvers reduce glymphatic clearance?

artículo científico publicado en 2016

Evidence for the existence of a communication between the eye and the brain?

artículo científico publicado en 2017

Fast circulation of cerebrospinal fluid: an alternative perspective on the protective role of high intracranial pressure in ocular hypertension

artículo científico

Fibromyalgia as a glymphatic overload syndrome.

artículo científico publicado en 2018

Genes involved in cerebrospinal fluid production as candidate genes for late-onset Alzheimer's disease: a hypothesis

artículo científico publicado en 2011

Glaucoma and the Role of Cerebrospinal Fluid Dynamics

artículo científico publicado en 2015

Glaucoma as a dangerous interplay between ocular fluid and cerebrospinal fluid

artículo científico publicado en 2019

Glaucoma considered as an imbalance between production and clearance of neurotoxins

artículo científico publicado en 2014

Glymphatic stasis at the site of the lamina cribrosa as a potential mechanism underlying open-angle glaucoma

artículo científico publicado en 2017

High occurrence rate of glaucoma among patients with normal pressure hydrocephalus

artículo científico publicado en 2010

Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal-tension glaucoma.

artículo científico publicado en 2018

Increased Cerebrospinal Fluid Production as a Possible Mechanism Underlying Caffeine's Protective Effect against Alzheimer's Disease

artículo científico publicado en 2011

Intracranial pressure and glaucoma: Is there a new therapeutic perspective on the horizon?

artículo científico publicado en 2018

Intracranial pressure fluctuations: a potential risk factor for glaucoma?

artículo científico publicado en 2013

Intracranial pressure-induced optic nerve sheath response as a predictive biomarker for optic disc edema in astronauts

artículo científico publicado en 2017

Intrathecal cerebrospinal fluid infusion as a potential therapeutic strategy for Alzheimer's disease

artículo científico publicado en 2018

Is extensive use of the Valsalva maneuver associated with an increased risk for Alzheimer's disease?

artículo científico publicado en 2005

Is the optic nerve compartment syndrome implicated in the pathogenesis of the high-tension form of primary open-angle glaucoma?

scientific article published on 25 December 2019

Letter to the Editor. Low ICP and normal tension glaucoma: optic nerve damage due to barotraumatic factors, failure of CSF dynamics, or both?

artículo científico publicado en 2018

Letter: Brain Physiological Response and Adaptation During Spaceflight

scientific article published on 01 February 2020

More advanced Alzheimer's disease may be associated with a decrease in cerebrospinal fluid pressure

artículo científico publicado en 2009

Normal-tension glaucoma and Alzheimer's disease: hypothesis of a possible common underlying risk factor.

artículo científico publicado en 2006

Optic Disc Swelling in Astronauts: A Manifestation of "Glymphedema"?

artículo científico publicado en 2019

Optic Nerve Sheath Distention as a Protective Mechanism Against the Visual Impairment and Intracranial Pressure Syndrome in Astronauts

artículo científico publicado en 2017

Potential Involvement of the Ocular Glymphatic System in Optic Disc Edema in Astronauts

artículo científico publicado en 2020

Pressure and velocity in intraocular and subarachnoid space fluid chambers: an inseparable couple

artículo científico publicado en 2018

Re: Stenger et al.: Focus on the optic nerve head in spaceflight-associated neuro-ocular syndrome (Ophthalmology. 2019;126:1604-1606)

scientific article published on 01 June 2020

Retinal nerve fiber layer thinning in chronic fatigue syndrome as a possible ocular biomarker of underlying glymphatic system dysfunction

scientific article published on 04 October 2019

Senescent changes in cerebrospinal fluid circulatory physiology and their role in the pathogenesis of normal-tension glaucoma.

artículo científico

Targeting the Cerebrospinal Fluid Compartment in Glaucoma: Still the Dark Side of the Moon? Comment on Passaro et al. Glaucoma as a Tauopathy—Is It the Missing Piece in the Glaucoma Puzzle? J. Clin. Med. 2023, 12, 6900

artículo científico publicado en 2024

The "Ocular Glymphatic System": An Important Missing Piece in the Puzzle of Optic Disc Edema in Astronauts?

artículo científico publicado en 2018

The "ocular glymphatic clearance system": a key missing piece of the Alzheimer's disease-glaucoma puzzle found?

artículo científico publicado en 2020

The First Histologic Evidence of a Paravascular Pathway Within the Optic Nerve.

artículo científico publicado en 2018

The Glymphatic Hypothesis of Glaucoma: A Unifying Concept Incorporating Vascular, Biomechanical, and Biochemical Aspects of the Disease

artículo científico publicado en 2017

The Glymphatic System: A New Player in Ocular Diseases?

artículo científico publicado en 2016

The Possible Role of Elastic Properties of the Brain and Optic Nerve Sheath in the Development of Spaceflight-Associated Neuro-Ocular Syndrome

artículo científico publicado en 2020

The Valsalva maneuver and Alzheimer's disease: is there a link?

artículo científico publicado en 2009

The buffering capacity of the brain and optic nerve against spaceflight-associated neuro-ocular syndrome

artículo científico publicado en 2019

The escape of retrobulbar cerebrospinal fluid in the astronaut's eye: mission impossible?

scientific article published on 07 May 2019

The perivascular space of the central retinal artery as a potential major cerebrospinal fluid inflow route: implications for optic disc edema in astronauts

scientific article published on 20 September 2019

The putative glymphatic signature of chronic fatigue syndrome: A new view on the disease pathogenesis and therapy

article

The retinal nerve fiber layer as a window to the glymphatic system

artículo científico publicado en 2019

The role of low intracranial pressure in the development of glaucoma in patients with Alzheimer's disease

artículo científico publicado en 2014

The two faces of the translaminar pressure difference: the biomechanical one and the biochemical one.

artículo científico publicado en 2016

Why Space Flight-Associated Neuro-ocular Syndrome May Differ From Idiopathic Intracranial Hypertension.

artículo científico publicado en 2018

Why a One-Way Ticket to Mars May Result in a One-Way Directional Glymphatic Flow to the Eye.

artículo científico publicado en 2017