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2-Arachidonoylglycerol stimulates activator protein-1-dependent transcriptional activity and enhances epidermal growth factor-induced cell transformation in JB6 P+ cells

artículo científico publicado en 2005

A Rising Cancer Prevention Target of RSK2 in Human Skin Cancer

artículo científico publicado el 5 de agosto de 2013

A novel role for mixed-lineage kinase-like mitogen-activated protein triple kinase alpha in neoplastic cell transformation and tumor development

artículo científico publicado en 2004

A novel role of brain-type ACS4 isotype in neuronal differentiation

artículo científico publicado el 15 de febrero de 2012

A regulatory mechanism for RSK2 NH(2)-terminal kinase activity

artículo científico publicado en 2009

A selective small-molecule inhibitor of c-Jun N-terminal kinase 1

artículo científico publicado en 2009

Ataxia telangiectasia mutated proteins, MAPKs, and RSK2 are involved in the phosphorylation of STAT3.

artículo científico publicado en 2003

Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells

artículo científico publicado en 2013

COOH-terminal Src kinase-mediated c-Jun phosphorylation promotes c-Jun degradation and inhibits cell transformation.

artículo científico publicado en 2006

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

artículo científico publicado en 2006

Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity

artículo científico publicado en 2007

Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation

artículo científico publicado en 2008

Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation.

artículo científico publicado en 2009

Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation

scientific article published on 01 March 2007

Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death

artículo científico publicado en 2024

ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal

scientific article published on 13 April 2014

Effects of MAP kinase inhibitors on epidermal growth factor-induced neoplastic transformation of human keratinocytes

artículo científico publicado en 2006

Embryonic stem‐cell‐preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells

artículo científico publicado el 16 de agosto de 2011

Epimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells

scientific article published on 18 March 2019

Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway

artículo científico publicado en 2007

Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation

artículo científico publicado el 22 de noviembre de 2010

Extracellular signal-regulated kinase 8-mediated c-Jun phosphorylation increases tumorigenesis of human colon cancer

artículo científico publicado en 2010

Fyn is a novel target of (-)-epigallocatechin gallate in the inhibition of JB6 Cl41 cell transformation

artículo científico publicado en 2008

Genetic ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17

artículo científico publicado en 2015

Involvement of the paxillin pathway in JB6 Cl41 cell transformation

artículo científico publicado en 2006

Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR.

artículo científico publicado en 2014

JNK1 and 2 play a negative role in reprogramming to pluripotent stem cells by suppressing Klf4 activity

artículo científico publicado en 2013

Lapatinib, a Preventive/Therapeutic Agent against Mammary Cancer, Suppresses RTK-Mediated Signaling through Multiple Signaling Pathways

artículo científico publicado el 26 de julio de 2011

MST1 promotes apoptosis through phosphorylation of histone H2AX

artículo científico publicado en 2010

Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells.

artículo científico publicado en 2018

Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation

artículo científico publicado en 2008

Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1.

artículo científico publicado en 2007

Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth

artículo científico publicado en 2012

Nuclear factor of activated T3 is a negative regulator of Ras-JNK1/2-AP-1 induced cell transformation

artículo científico publicado en 2007

Phosphorylation of H2AX at Ser139 and a new phosphorylation site Ser16 by RSK2 decreases H2AX ubiquitination and inhibits cell transformation

artículo científico publicado en 2011

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha

artículo científico publicado en 2005

Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells

artículo científico publicado el 1 de diciembre de 2010

Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines

artículo científico publicado en 2011

Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.

artículo científico publicado en 2010

Phosphorylation of histone H2B serine 32 is linked to cell transformation.

artículo científico publicado en 2011

Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation

artículo científico publicado en 2005

Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.

artículo científico publicado en 2011

RSK2 and its binding partners in cell proliferation, transformation and cancer development.

artículo científico publicado en 2016

RSK2 as a key regulator in human skin cancer

artículo científico publicado en 2012

RSK2 mediates NF-{kappa}B activity through the phosphorylation of IkappaBalpha in the TNF-R1 pathway.

artículo científico publicado en 2010

Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase

artículo científico publicado en 2004

Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase

artículo científico publicado en 2010

Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation

artículo científico publicado en 2007

Role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells

artículo científico publicado en 2010

Simultaneous quantification of 18 saturated and unsaturated fatty acids and 7 sterols as their tert-butyldimethylsilyl derivatives in human saliva using gas chromatography-tandem mass spectrometry

artículo científico publicado en 2018

Stat2 stability regulation: an intersection between immunity and carcinogenesis

scientific article published on 25 September 2020

Sunlight UV-induced skin cancer relies upon activation of the p38α signaling pathway

artículo científico publicado en 2013

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway

scientific journal article

T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation

artículo científico publicado en 2007

Targeting PRPK and TOPK for skin cancer prevention and therapy

scientific article published on 14 June 2018

The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development

artículo científico publicado en 2008

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

artículo científico publicado en 2005

The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1

artículo científico publicado en 2015

The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity

artículo científico publicado en 2005

Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.

artículo científico publicado en 2006

Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.

artículo científico publicado en 2009

[6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase

artículo científico publicado en 2009

p38 Mitogen-activated protein kinase regulation of JB6 Cl41 cell transformation promoted by epidermal growth factor

artículo científico publicado en 2003