Lista de obras -

Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients.

artículo científico publicado en 2019

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

scientific article published on 01 January 2019

Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation

artículo científico publicado en 2008

Comparative genomic analysis of oral versus laryngeal and pharyngeal cancer

artículo científico publicado en 2018

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

artículo científico publicado en 2020

Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

artículo científico publicado en 2020

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

artículo científico publicado en 2018

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC

artículo científico publicado en 2019

Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy

artículo científico publicado en 2020

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells

artículo científico publicado en 2015

Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.

artículo científico publicado en 2018

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy.

artículo científico publicado en 2019

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

artículo científico publicado en 2014

Histopathology-derived modeling of prostate cancer tumor control probability: Implications for the dose to the tumor and the gland.

artículo científico publicado en 2016

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

artículo científico publicado en 2017

Improved pharmacodynamic (PD) assessment of low dose PARP inhibitor PD activity for radiotherapy and chemotherapy combination trials

artículo científico publicado en 2017

Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays

artículo científico publicado en 2007

Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells

artículo científico publicado en 2007

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

artículo científico publicado en 2008

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study

artículo científico publicado en 2014

New challenge of developing combined radio-drug therapy

scientific article published on 01 June 2014

Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective

artículo científico publicado en 2010

Ovarian cancer-derived copy number alterations signatures are prognostic in chemoradiotherapy-treated head and neck squamous cell carcinoma

artículo científico publicado en 2020

Phase 1 and pharmacological study of olaparib in combination with high-dose radiotherapy with and without concurrent cisplatin for non-small cell lung cancer

artículo científico publicado en 2020

Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons

artículo científico publicado en 2012

Radiosensitization by a dominant negative to DNA polymerase beta is DNA polymerase beta-independent and XRCC1-dependent

artículo científico publicado en 2005

Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status

artículo científico publicado en 2005

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

artículo científico publicado en 2015

Role for DNA polymerase beta in response to ionizing radiation

artículo científico publicado en 2006

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

artículo científico publicado en 2018

Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2).

artículo científico publicado en 2008

Strategies to improve radiotherapy with targeted drugs

artículo científico publicado en 2011

Targeted Radiosensitization of Cells Expressing Truncated DNA Polymerase β ⬇️

artículo científico publicado el 26 de octubre de 2010

Targeting base excision repair as a sensitization strategy in radiotherapy

artículo científico publicado en 2010

The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells

artículo científico publicado en 2002

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.

artículo científico publicado en 2014

Lista de obras de

Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients.

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation

Comparative genomic analysis of oral versus laryngeal and pharyngeal cancer

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC

Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells

Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy.

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

Histopathology-derived modeling of prostate cancer tumor control probability: Implications for the dose to the tumor and the gland.

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

Improved pharmacodynamic (PD) assessment of low dose PARP inhibitor PD activity for radiotherapy and chemotherapy combination trials

Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays

Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study

New challenge of developing combined radio-drug therapy

Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective

Ovarian cancer-derived copy number alterations signatures are prognostic in chemoradiotherapy-treated head and neck squamous cell carcinoma

Phase 1 and pharmacological study of olaparib in combination with high-dose radiotherapy with and without concurrent cisplatin for non-small cell lung cancer

Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons

Radiosensitization by a dominant negative to DNA polymerase beta is DNA polymerase beta-independent and XRCC1-dependent

Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

Role for DNA polymerase beta in response to ionizing radiation

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2).

Strategies to improve radiotherapy with targeted drugs

Targeted Radiosensitization of Cells Expressing Truncated DNA Polymerase β ⬇️

Targeting base excision repair as a sensitization strategy in radiotherapy

The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.