Lista de obras -

A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC

artículo científico publicado en 2021

A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies

artículo científico publicado en 2019

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit ⬇️

artículo científico publicado el 6 de junio de 2012

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility

scientific article published on 27 May 2020

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

artículo científico publicado en 2020

Brain Penetrant LRRK2 Inhibitor

artículo científico publicado en 2012

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

artículo científico publicado en 2012

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

artículo científico

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

artículo científico publicado en 2011

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

scientific article published on 13 August 2020

Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities

scientific article published on 19 June 2018

Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors ⬇️

artículo científico publicado el 15 de marzo de 2011

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors ⬇️

artículo científico publicado el 14 de octubre de 2010

GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor

artículo científico publicado en 2012

High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors

artículo científico publicado en 2011

Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 – 2011) ⬇️

artículo científico publicado el 6 de noviembre de 2012

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

artículo científico publicado en 2022

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

scientific article published on 23 August 2018

Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein ⬇️

artículo científico publicado el 14 de septiembre de 2010

Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase

artículo científico publicado en 2012

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

artículo científico publicado en 2018

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

artículo científico publicado en 2013

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

artículo científico publicado en 2020

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

artículo científico publicado en 2013

Lista de obras de

A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC

A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit ⬇️

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

Brain Penetrant LRRK2 Inhibitor

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities

Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors ⬇️

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors ⬇️

GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor

High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors

Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 – 2011) ⬇️

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein ⬇️

Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor