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A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy

artículo científico publicado en 2019

Adverse outcome pathways: opportunities, limitations and open questions

artículo científico publicado en 2017

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

artículo científico publicado en 2016

Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants

scientific article published on 12 June 2019

FAIR High Content Screening in Bioimaging

artículo científico publicado en 2023

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

scientific article published on 27 August 2019

Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer

artículo científico publicado en 2019

Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals

scientific article published on 30 June 2020

Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors

artículo científico publicado en 2021

Papyrus: a large-scale curated dataset aimed at bioactivity predictions

artículo científico publicado en 2023

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

artículo científico publicado en 2019

The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment

artículo científico publicado en 2021

The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example

artículo científico publicado en 2021

Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project

artículo científico publicado en 2019

Toxicogenomics directory of chemically exposed human hepatocytes

artículo científico publicado en 2014

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