Lista de obras -

A Search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: a pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute).

artículo científico publicado en 2008

Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids

artículo científico publicado en 2009

Altered proteasome function in right ventricular hypertrophy

scientific article published on 01 February 2020

Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis

artículo científico publicado en 2014

Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis.

artículo científico publicado en 2015

Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis

artículo científico publicado en 2016

An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid

artículo científico publicado en 2002

Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA

artículo científico publicado en 2007

Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

artículo científico publicado en 2015

Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

artículo científico publicado en 2020

Biophysical inhibition of pulmonary surfactant function by polymeric nanoparticles: Role of surfactant protein B and C

artículo científico publicado en 2014

Biophysical inhibition of synthetic vs. naturally-derived pulmonary surfactant preparations by polymeric nanoparticles

scientific article published on 01 November 2013

Bronchoscopic surfactant administration preserves gas exchange and pulmonary compliance after single lung transplantation in dogs

artículo científico publicado en 2004

Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis

artículo científico publicado en 2017

Cell-specific nitric oxide synthase-isoenzyme expression and regulation in response to endotoxin in intact rat lungs

artículo científico publicado en 2002

Changes in biochemical and biophysical surfactant properties with cardiopulmonary bypass in children

artículo científico publicado en 2003

Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis

artículo científico publicado en 2004

Characteristics and outcomes of a cohort hospitalized for pandemic and seasonal influenza in Germany based on nationwide inpatient data.

artículo científico

Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin

artículo científico publicado en 2002

Chemical crosslinking of urokinase to pulmonary surfactant protein B for targeting alveolar fibrin.

artículo científico publicado en 2003

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides

scientific article published on 01 April 2020

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

artículo científico publicado en 2003

Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application

artículo científico publicado en 2004

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.

artículo científico publicado en 2015

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

artículo científico publicado en 2017

Depletion of <i>Numb</i> and <i>Numblike</i> in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway

artículo científico publicado en 2021

Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide

artículo científico publicado en 2002

Dry powder aerosolization of a recombinant surfactant protein-C-based surfactant for inhalative treatment of the acutely inflamed lung

artículo científico publicado en 2010

Effects of a recombinant surfactant protein-C-based surfactant on lung function and the pulmonary surfactant system in a model of meconium aspiration syndrome.

artículo científico publicado en 2006

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

artículo científico publicado en 2010

Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia

artículo científico publicado en 2010

Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases: Rationale, Aims, and Design of a Nationwide Prospective Registry--The EXCITING-ILD Registry

artículo científico publicado en 2015

Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, phase II trial

artículo científico publicado en 2017

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

artículo científico publicado en 2009

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

artículo científico publicado en 2007

FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury

Fibrinolysis-inhibitory capacity of clot-embedded surfactant is enhanced by SP-B and SP-C

scientific article published on 06 September 2002

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis

artículo científico publicado en 2018

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017

artículo científico publicado en 2017

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017

artículo científico publicado en 2017

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017.

artículo científico publicado en 2018

Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant

article

IRE1 Signaling As a Putative Therapeutic Target in Influenza Virus-induced Pneumonia

artículo científico publicado en 2019

Identification a novel subset of alveolar type 2 cells expanding following pneumonectomy and enriched in PD-L1

artículo científico publicado en 2020

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

artículo científico publicado en 2020

Impact of surface tension on the conversion rate of large to small surfactant aggregates

artículo científico publicado en 2003

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis

artículo científico publicado en 2019

Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia

artículo científico publicado en 2004

Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis

artículo científico publicado en 2015

Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation ⬇️

artículo científico publicado el 3 de enero de 2013

Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model

artículo científico publicado en 2010

Is fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling?

artículo científico publicado en 2018

Ischemic and endotoxin pre-conditioning reduce lung reperfusion injury-induced surfactant alterations

artículo científico publicado en 2005

Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model

artículo científico publicado en 2015

Liver carboxylesterase cleaves surfactant protein (SP-) B and promotes surfactant subtype conversion

artículo científico publicado en 2006

Long-term safety of pirfenidone: results of the prospective, observational PASSPORT study

scientific article published on 19 October 2018

Lungenfibrosen—ein therapeutisches Dilemma?

scientific article published on 01 April 2006

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

artículo científico

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

scientific article published on 05 July 2019

Multilineage murine stem cells generate complex organoids to model distal lung development and disease

scientific article published on 28 September 2020

NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

artículo científico publicado en 2020

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

artículo científico publicado en 2011

Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate

artículo científico publicado en 2016

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

artículo científico publicado en 2016

Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment

artículo científico publicado en 2015

Panobinostat plus bortezomib and dexamethasone: impact of dose intensity and administration frequency on safety in the PANORAMA 1 trial.

artículo científico publicado en 2017

Phenotypes of organ involvement in sarcoidosis

artículo científico publicado en 2018

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

artículo científico publicado en 2010

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis

artículo científico publicado en 2013

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation

artículo científico publicado en 2021

Positive end-expiratory pressure modifies response to recombinant and natural exogenous surfactant in ventilated immature newborn rabbits

artículo científico publicado en 2005

Potential applications of flat-panel volumetric CT in morphologic and functional small animal imaging

artículo científico publicado en 2005

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits

artículo científico publicado en 2003

Proteasome activator PA200 regulates myofibroblast differentiation

artículo científico publicado en 2019

Pulmonary hypertension due to chronic lung disease: updated Recommendations of the Cologne Consensus Conference 2011.

artículo científico

Pulmonary surfactant in patients with Pneumocystis pneumonia and acquired immunodeficiency syndrome

artículo científico publicado en 2006

Recombinant Surfactant Protein C–based Surfactant for Patients with Severe Direct Lung Injury ⬇️

artículo científico publicado el 10 de diciembre de 2010

Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase

artículo científico publicado en 2008

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells

scientific article published on 26 April 2019

Regulation of 26S Proteasome Activity in Pulmonary Fibrosis

artículo científico publicado en 2015

Regulation of immunoproteasome function in the lung

artículo científico publicado en 2015

Riociguat for interstitial lung disease and pulmonary hypertension: a pilot trial.

artículo científico publicado en 2012

SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension

artículo científico publicado en 2022

Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial.

artículo científico publicado en 2016

Selective inhibition of large-to-small surfactant aggregate conversion by serine protease inhibitors of the bis-benzamidine type

artículo científico publicado en 2003

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

artículo científico

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

artículo científico publicado en 2002

Soluble polysialylated NCAM: a novel player of the innate immune system in the lung

artículo científico publicado en 2013

Surfactant abnormalities after single lung transplantation in dogs: impact of bronchoscopic surfactant administration

artículo científico publicado en 2004

Surfactant replacement therapy in ARDS.

artículo científico publicado en 2009

TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury

artículo científico publicado en 2013

Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension

scientific article published on 14 October 2020

The Ariane-IPF ERS Clinical Research Collaboration: seeking collaboration through launch of a federation of European registries on idiopathic pulmonary fibrosis

artículo científico publicado en 2019

The Collaborative Metadata Repository (CoMetaR) Web App: Quantitative and Qualitative Usability Evaluation

artículo científico publicado en 2021

The FLORA study: presenting a novel IPF trial design

scientific article published on 27 June 2018

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis

artículo científico publicado en 2019

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

scientific article published on 01 December 2019

The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis

artículo científico publicado en 2007

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis

artículo científico publicado en 2011

The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis.

artículo científico publicado en 2015

Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis

scientific article published on 01 April 2017

Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.

artículo científico publicado en 2016

Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis ⬇️

artículo científico publicado el 1 de junio de 2012

WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis ⬇️

artículo científico publicado el 1 de julio de 2013

WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

artículo científico publicado en 2009

miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development.

artículo científico publicado en 2014

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de

A Search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: a pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute).

Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids

Altered proteasome function in right ventricular hypertrophy

Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis

Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis.

Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis

An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid

Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA

Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

Biophysical inhibition of pulmonary surfactant function by polymeric nanoparticles: Role of surfactant protein B and C

Biophysical inhibition of synthetic vs. naturally-derived pulmonary surfactant preparations by polymeric nanoparticles

Bronchoscopic surfactant administration preserves gas exchange and pulmonary compliance after single lung transplantation in dogs

Cell-specific expression of runt-related transcription factor 2 contributes to pulmonary fibrosis

Cell-specific nitric oxide synthase-isoenzyme expression and regulation in response to endotoxin in intact rat lungs

Changes in biochemical and biophysical surfactant properties with cardiopulmonary bypass in children

Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis

Characteristics and outcomes of a cohort hospitalized for pandemic and seasonal influenza in Germany based on nationwide inpatient data.

Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin

Chemical crosslinking of urokinase to pulmonary surfactant protein B for targeting alveolar fibrin.

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

Depletion of <i>Numb</i> and <i>Numblike</i> in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway

Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide

Dry powder aerosolization of a recombinant surfactant protein-C-based surfactant for inhalative treatment of the acutely inflamed lung

Effects of a recombinant surfactant protein-C-based surfactant on lung function and the pulmonary surfactant system in a model of meconium aspiration syndrome.

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia

Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases: Rationale, Aims, and Design of a Nationwide Prospective Registry--The EXCITING-ILD Registry

Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, phase II trial

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury

Fibrinolysis-inhibitory capacity of clot-embedded surfactant is enhanced by SP-B and SP-C

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017

German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017.

Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant

IRE1 Signaling As a Putative Therapeutic Target in Influenza Virus-induced Pneumonia

Identification a novel subset of alveolar type 2 cells expanding following pneumonectomy and enriched in PD-L1

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

Impact of surface tension on the conversion rate of large to small surfactant aggregates

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis

Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia

Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis

Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation ⬇️

Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model

Is fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling?

Ischemic and endotoxin pre-conditioning reduce lung reperfusion injury-induced surfactant alterations

Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model

Liver carboxylesterase cleaves surfactant protein (SP-) B and promotes surfactant subtype conversion

Long-term safety of pirfenidone: results of the prospective, observational PASSPORT study

Lungenfibrosen—ein therapeutisches Dilemma?

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Multilineage murine stem cells generate complex organoids to model distal lung development and disease

NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment

Panobinostat plus bortezomib and dexamethasone: impact of dose intensity and administration frequency on safety in the PANORAMA 1 trial.

Phenotypes of organ involvement in sarcoidosis

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation

Positive end-expiratory pressure modifies response to recombinant and natural exogenous surfactant in ventilated immature newborn rabbits

Potential applications of flat-panel volumetric CT in morphologic and functional small animal imaging

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits

Proteasome activator PA200 regulates myofibroblast differentiation

Pulmonary hypertension due to chronic lung disease: updated Recommendations of the Cologne Consensus Conference 2011.

Pulmonary surfactant in patients with Pneumocystis pneumonia and acquired immunodeficiency syndrome

Recombinant Surfactant Protein C–based Surfactant for Patients with Severe Direct Lung Injury ⬇️

Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells