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A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.

artículo científico publicado en 2015

A systematic analysis of genetic interactions and their underlying biology in childhood cancer

artículo científico publicado en 2021

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

scientific article published on 11 March 2020

Cell cycle population effects in perturbation studies

artículo científico publicado en 2014

Functional overlap and regulatory links shape genetic interactions between signaling pathways.

artículo científico publicado en 2010

Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development

artículo científico publicado en 2012

Genome-wide off-rates reveal how DNA binding dynamics shape transcription factor function

artículo científico publicado en 2020

Insulin-FOXO3 signaling modulates circadian rhythms via regulation of clock transcription.

artículo científico publicado en 2014

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

artículo científico publicado en 2014

Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2

scientific journal article

Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.

artículo científico publicado en 2012

Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters.

artículo científico publicado en 2016

Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons

artículo científico publicado en 2011

Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline-auxotroph yeast

artículo científico publicado en 2021

Single cell derived mRNA signals across human kidney tumors

scientific article published on 23 June 2021

The role of Ctk1 kinase in termination of small non-coding RNAs

artículo científico publicado en 2013