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131I-3F8: clinical validation of imaging studies and therapeutic applications

scientific article published on 01 January 1991

3F8 monoclonal antibody treatment of patients with stage 4 neuroblastoma: a phase II study ⬇️

artículo científico publicado el 1 de junio de 1998

3F8 monoclonal antibody treatment of patients with stage IV neuroblastoma: a phase II study

artículo científico publicado en 1994

99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors

artículo científico publicado en 1999

A Self-Assembling and DisAssembling (SADA) bispecific antibody (BsAb) platform for curative 2-step pre-targeted radioimmunotherapy

scientific article published on 21 September 2020

A Three-Gene Expression Signature Model for Risk Stratification of Patients with Neuroblastoma ⬇️

artículo científico publicado el 10 de febrero de 2012

A distinct gene expression signature characterizes human neuroblastoma cancer stem cells

artículo científico publicado en 2015

A dual-specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma

artículo científico publicado en 2015

A focal lesion in the falx cerebri: Harbinger of classic stage 4 neuroblastoma in an infant cured despite residual disease after minimal therapy.

artículo científico publicado en 2009

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors

artículo científico publicado en 2017

A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma

artículo científico publicado en 2016

A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma.

artículo científico publicado en 2017

A potent tetravalent T-cell-engaging bispecific antibody against CD33 in acute myeloid leukemia

scientific article published on 01 June 2018

ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures

scientific article published on 17 October 2019

Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity ⬇️

artículo científico publicado el 15 de marzo de 1992

Activation of peripheral-blood granulocytes is strongly correlated with patient outcome after immunotherapy with anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating factor

artículo científico publicado en 2011

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

scientific article published on 10 May 2018

Allelic loss of chromosome 1p in neuroblastoma

artículo científico publicado en 1996

Alpha radioimmunotherapy using 225Ac-proteus-DOTA for solid tumors - safety at curative doses

artículo científico publicado en 2020

Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8

artículo científico publicado en 2015

An N-Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy

artículo científico publicado en 2020

Analysis of GD2/GM2 synthase mRNA as a biomarker for small cell lung cancer

artículo científico publicado en 2009

Anti-G(D2) antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age

artículo científico publicado en 1998

Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

artículo científico publicado en 2013

Anti-idiotypic antibody as the surrogate antigen for cloning scFv and its fusion proteins

artículo científico publicado en 2002

Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy

artículo científico publicado en 2003

Antibody response to murine anti-GD2 monoclonal antibodies: correlation with patient survival

artículo científico publicado en 1994

Antibody-based targeted radiation to pediatric tumors.

artículo científico publicado en 2005

Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering

artículo científico publicado en 2016

Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study

artículo científico publicado en 2016

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

artículo científico publicado en 2012

Assessment of pulmonary outcomes, exercise capacity, and longitudinal changes in lung function in pediatric survivors of high-risk neuroblastoma

artículo científico publicado en 2019

Association between molecular detection of GAGE and survival in patients with malignant melanoma: a retrospective cohort study

artículo científico publicado en 1999

Association of CYP 3 A 4 genotype with treatment-related leukemia ⬇️

artículo científico publicado el 27 de octubre de 1998

Association of age at diagnosis and genetic mutations in patients with neuroblastoma.

artículo científico publicado en 2012

Autografting with bone marrow exposed to multiple courses of very high dose cyclophosphamide in vivo and to 4-hydroperoxycyclophosphamide in vitro

artículo científico publicado en 1990

Autologous bone marrow transplantation in children with advanced neuroblastoma

artículo científico publicado en 1995

B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study

artículo científico publicado en 2020

Biodistribution and Dosimetry of Intraventricularly Administered 124I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors

scientific article published on 12 August 2019

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

artículo científico publicado en 2003

Bispecific antibody does not induce T-cell death mediated by chimeric antigen receptor against disialoganglioside GD2.

artículo científico publicado en 2017

Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy

artículo científico publicado en 2015

Brain-sparing radiotherapy for neuroblastoma skull metastases

artículo científico publicado en 2008

CMET-28. IMPACT OF DISEASE SITE, SIZE AND SURGICAL RESECTION ON SURVIVAL FROM METASTATIC CNS NEUROBLASTOMA

Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma

artículo científico publicado en 2004

Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells

artículo científico publicado en 2020

Characteristics of stem cells from human neuroblastoma cell lines and in tumors

artículo científico publicado en 2004

Checkpoint kinase inhibitor synergizes with DNA‐damaging agents in G1 checkpoint‐defective neuroblastoma ⬇️

artículo científico publicado el 8 de marzo de 2011

Chimeric antigen receptors and bispecific antibodies to retarget T cells in pediatric oncology

artículo científico

Chronic neuroblastoma

artículo científico publicado en 2002

Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.

artículo científico publicado en 2000

Clinically critical impact of molecular genetic studies in pediatric solid tumors

scientific article published on 01 December 1999

Clinically effective monoclonal antibody 3F8 mediates nonoxidative lysis of human neuroectodermal tumor cells by polymorphonuclear leukocytes ⬇️

artículo científico publicado el 15 de septiembre de 1991

Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma

artículo científico publicado en 2004

Combination of bevacizumab, irinotecan, and temozolomide for refractory or relapsed neuroblastoma: Results of a phase II study

artículo científico publicado en 2017

Comparison of the targeting characteristics of various radioimmunoconjugates for radioimmunotherapy of neuroblastoma: dosimetry calculations incorporating cross-organ beta doses

artículo científico publicado en 1996

Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma

artículo científico publicado en 2009

Comprehensive analysis of tumoral DNA content reveals clonal ploidy heterogeneity as a marker with prognostic significance in locoregional neuroblastoma

artículo científico publicado en 2007

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.

artículo científico publicado en 2018

Correlation of MYCN amplification, Trk-A and CD44 expression with clinical stage in 250 patients with neuroblastoma ⬇️

artículo científico publicado el 1 de octubre de 1997

Correlation of anti-idiotype network with survival following anti-G(D2) monoclonal antibody 3F8 therapy of stage 4 neuroblastoma

artículo científico publicado en 2000

Curability of recurrent disseminated disease after surgery alone for local-regional neuroblastoma using intensive chemotherapy and anti-G(D2) immunotherapy

artículo científico publicado en 2003

Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer

artículo científico publicado en 2017

Current status of radioimmunotherapy ⬇️

artículo científico publicado el 1 de julio de 1994

Cyclin D1, a novel molecular marker of minimal residual disease, in metastatic neuroblastoma

artículo científico publicado en 2007

Cyclophosphamide and the heart

artículo científico publicado en 1991

Cyclophosphamide versus ifosfamide in paediatric oncology

artículo científico publicado en 1990

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis

artículo científico publicado en 2014

Desmoplastic small round cell tumor 20 years after its discovery

artículo científico publicado en 2015

Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy

artículo científico publicado en 1996

Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

artículo científico publicado en 2000

Detection of metastatic neuroblastoma in bone marrow: when is routine marrow histology insensitive? ⬇️

artículo científico publicado el 1 de agosto de 1997

Detection of microscopic disease: comparing histology, immunocytology, and RT-PCR of tyrosine hydroxylase, GAGE, and MAGE.

artículo científico publicado en 2001

Detection of microscopic neuroblastoma in marrow by histology, immunocytology, and reverse transcription-PCR of multiple molecular markers

scientific article published on 01 November 1998

Detection of neuroblastoma in bone marrow by immunocytology: is a single marrow aspirate adequate?

artículo científico publicado en 1999

Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers

artículo científico publicado en 2018

Development of a method to measure kinetics of radiolabelled monoclonal antibody in human tumour with applications to microdosimetry: positron emission tomography studies of iodine-124 labelled 3F8 monoclonal antibody in glioma

artículo científico publicado en 1993

Differential expression of genes mapping to recurrently abnormal chromosomal regions characterize neuroblastic tumours with distinct ploidy status

artículo científico publicado en 2008

Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma

artículo científico publicado en 2010

Disaloganglioside GD2 loss following monoclonal antibody therapy is rare in neuroblastoma.

artículo científico publicado en 2001

Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma ⬇️

artículo científico publicado el 1 de septiembre de 1998

Disialoganglioside GD2 and a novel tumor antigen: potential targets for immunotherapy of desmoplastic small round cell tumor

scientific article published on 01 December 2002

Disialoganglioside GD2 anti-idiotypic monoclonal antibodies

artículo científico publicado en 1993

Disialoganglioside directed immunotherapy of neuroblastoma

artículo científico publicado en 2007

Dose-escalation is needed for gross disease in high-risk neuroblastoma.

artículo científico publicado en 2018

Dose-intensity analysis and randomized trials

artículo científico publicado en 1991

Dose-intensive use of cyclophosphamide in ablation of neuroblastoma

artículo científico publicado en 1990

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma.

artículo científico publicado en 2005

EPEN-04. RECURRENT EPENDYMOMA: ROLE OF INTRAVENTRICULAR TARGETED RADIOIMMUNOTHERAPY

Early Molecular Response of Marrow Disease to Biologic Therapy Is Highly Prognostic in Neuroblastoma ⬇️

artículo científico publicado el 15 de octubre de 2003

Early negative minimal residual disease in bone marrow after immunotherapy is less predictive of late or non‐marrow relapse among patients with high‐risk stage 4 neuroblastoma ⬇️

artículo científico publicado el 17 de enero de 2013

Editorial: Bispecific Antibodies for T-Cell Based Immunotherapy

scientific article published on 09 December 2020

Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy

artículo científico publicado en 2013

Enteric neural crest differentiation in ganglioneuromas implicates Hedgehog signaling in peripheral neuroblastic tumor pathogenesis

artículo científico publicado en 2009

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

artículo científico publicado en 2009

Evaluation of widely consumed botanicals as immunological adjuvants

artículo científico publicado en 2008

Evolving significance of prognostic markers associated with new treatment strategies in neuroblastoma

artículo científico publicado en 2003

Evolving significance of prognostic markers associated with treatment improvement in patients with stage 4 neuroblastoma

artículo científico publicado en 2002

Exploiting Signaling Pathways and Immune Targets Beyond the Standard of Care for Ewing Sarcoma

artículo científico publicado en 2019

Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma

artículo científico publicado en 2008

Exploiting the MIBG-avidity of neuroblastoma for staging and treatment

artículo científico publicado en 2006

Expression of disialogangliosides GD2 and GD3 on human soft tissue sarcomas

artículo científico publicado en 1992

Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma

artículo científico publicado en 2010

Extending positron emission tomography scan utility to high-risk neuroblastoma: fluorine-18 fluorodeoxyglucose positron emission tomography as sole imaging modality in follow-up of patients

artículo científico publicado en 2001

FCGR2APolymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor

article by Nai-Kong V. Cheung et al published 20 June 2006 in Journal of Clinical Oncology

Favorable-biology neuroblastoma presenting with leptomeningeal metastases?: a case presentation

scientific article published on 01 November 2004

Five-day courses of irinotecan as palliative therapy for patients with neuroblastoma.

artículo científico publicado en 2005

GD2 synthase: a new molecular marker for detecting neuroblastoma

scientific article published on 01 August 2001

GD2-targeted immunotherapy and radioimmunotherapy

artículo científico publicado en 2014

GENE-05. ATRX IN-FRAME FUSION NEUROBLASTOMA IS SENSITIVE TO EZH2 INHIBITION VIA MODULATION OF NEURONAL GENE SIGNATURES

artículo científico publicado en 2019

GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma

artículo científico publicado en 1989

Generation of TCR-Like Antibodies Using Phage Display

artículo científico publicado en 2015

Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma.

artículo científico publicado en 2003

Genotyping Natural Killer Immune Checkpoints to Discover Biomarkers of Response

artículo científico publicado en 2017

Granulocyte-colony stimulating factor and multiple cycles of strongly myelosuppressive alkylator-based combination chemotherapy in children with neuroblastoma

artículo científico publicado en 2000

High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors ⬇️

artículo científico publicado el 1 de septiembre de 1998

High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan

artículo científico publicado en 2011

High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy

artículo científico publicado en 2007

High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma

artículo científico publicado en 2010

High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma

artículo científico publicado en 1991

Highly effective induction therapy for stage 4 neuroblastoma in children over 1 year of age.

artículo científico publicado en 1994

Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody

artículo científico publicado en 2015

Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

artículo científico publicado en 2018

Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo ⬇️

artículo científico publicado el 1 de julio de 2012

Hyperfractionated low-dose (21 Gy) radiotherapy for cranial skeletal metastases in patients with high-risk neuroblastoma.

artículo científico publicado en 2009

Hyperfractionated low-dose radiotherapy for high-risk neuroblastoma after intensive chemotherapy and surgery

artículo científico publicado en 2001

Hypothyroidism after 131I-monoclonal antibody treatment of neuroblastoma

artículo científico publicado en 2010

IMMU-05. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3

Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature

artículo científico

Imaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG.

artículo científico publicado en 2014

Immunotherapy of Childhood Sarcomas

artículo científico publicado en 2015

Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies

artículo científico publicado en 2020

Immunotherapy with GD2 specific monoclonal antibodies

artículo científico publicado en 1988

Impact of metaiodobenzylguanidine scintigraphy on assessing response of high-risk neuroblastoma to dose-intensive induction chemotherapy.

artículo científico publicado en 2003

Impact of minimal tumor burden on antibody response to vaccination ⬇️

artículo científico publicado el 26 de enero de 2011

Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma

artículo científico publicado en 2000

In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors

artículo científico publicado en 2013

In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma

artículo científico publicado en 2004

In vitro chemopurification of neuroblastoma cells: comparison of 6-hydroxydopamine and ascorbic acid with 4-hydroperoxycyclophosphamide

artículo científico publicado en 1989

Induction for high-risk neuroblastoma

artículo científico publicado en 2007

Induction of Ab3 and Ab3' antibody was associated with long-term survival after anti-G(D2) antibody therapy of stage 4 neuroblastoma

scientific article published on 01 July 2000

Insulin and glucose homeostasis in childhood cancer survivors treated with abdominal radiation: A pilot study

scholarly article by Danielle Novetsky Friedman et al published November 2018 in Pediatric Blood Cancer

Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number

artículo científico publicado en 2006

Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies

artículo científico publicado en 2020

International neuroblastoma staging system stage 1 neuroblastoma: a prospective study and literature review

artículo científico publicado en 1996

Interstitial infusion of glioma-targeted recombinant immunotoxin 8H9scFv-PE38.

artículo científico publicado en 2010

IntraOmmaya compartmental radioimmunotherapy using 131I-omburtamab-pharmacokinetic modeling to optimize therapeutic index

artículo científico publicado en 2020

Intraparenchymal and intratumoral interstitial infusion of anti-glioma monoclonal antibody 8H9.

artículo científico publicado en 2008

Irinotecan plus temozolomide for relapsed or refractory neuroblastoma.

artículo científico publicado en 2006

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

artículo científico publicado en 2009

KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma

artículo científico publicado en 2016

Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma

artículo científico publicado en 2014

Kinetics of primary tumor regression with chemotherapy: implications for the timing of surgery

scientific article published on 01 November 1996

Lack of early bevacizumab-related skeletal radiographic changes in children with neuroblastoma

scientific article published on 01 February 2009

Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin

artículo científico publicado en 2015

Laser-capture microdissected schwannian and neuroblastic cells in stage 4 neuroblastomas have the same genetic alterations

artículo científico publicado en 2000

Liver involvement in neuroblastoma: the Memorial Sloan-Kettering Experience supports treatment reduction in young patients

artículo científico publicado en 2006

Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma

artículo científico publicado en 2016

Long-term Pulmonary Outcomes in Pediatric Survivors of High-risk Neuroblastoma.

artículo científico publicado en 2017

Long-term complications in survivors of advanced stage neuroblastoma

artículo científico publicado en 2005

Long-term outcomes in survivors of neuroblastoma: a report from the Childhood Cancer Survivor Study

artículo científico publicado en 2009

Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma

artículo científico publicado en 2001

Low incidence of radionecrosis in children treated with conventional radiation therapy and intrathecal radioimmunotherapy

artículo científico publicado en 2015

MEDU-04. A PHASE II STUDY OF RADIOIMMUNOTHERAPY WITH INTRAVENTRICULAR 131I-3F8 FOR MEDULLOBLASTOMA.

artículo científico publicado en 2017

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas

artículo científico publicado en 2011

MYCN-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-GD2 immunotherapy.

artículo científico publicado en 2017

Major histocompatibility proteins, anti-Hu antibodies, and paraneoplastic encephalomyelitis in neuroblastoma and small cell lung cancer

artículo científico publicado en 1995

Management and outcome of stage 3 neuroblastoma

artículo científico publicado en 2008

Measuring circulating neuroblastoma cells by quantitative reverse transcriptase-polymerase chain reaction analysis

artículo científico publicado en 2004

Methionine depletion with recombinant methioninase: in vitro and in vivo efficacy against neuroblastoma and its synergism with chemotherapeutic drugs

scientific article published on April 2009

MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors

scientific article published on 07 July 2009

Molecular detection of GAGE expression in peripheral blood and bone marrow: utility as a tumor marker for neuroblastoma

artículo científico publicado en 1997

Molecular genetics of neuroblastoma and the implications for clinical management: a review of the MSKCC experience

artículo científico publicado en 2001

Monoclonal antibody 3F8 can effect durable remissions in neuroblastoma patients refractory to chemotherapy: a phase II trial

artículo científico publicado en 1991

Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors

artículo científico publicado en 2001

Monoclonal antibody therapies for solid tumors

scientific article published on 01 March 2009

Monoclonal antibody to human trk-A: diagnostic and therapeutic potential in neuroblastoma ⬇️

artículo científico publicado el 1 de octubre de 1997

Monoclonal antibody-based therapy of neuroblastoma

artículo científico publicado en 2001

Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission

artículo científico publicado en 2012

Myeloablative combination chemotherapy without total body irradiation for neuroblastoma

scientific article published on 01 February 1991

N7: a novel multi-modality therapy of high risk neuroblastoma (NB) in children diagnosed over 1 year of age.

artículo científico publicado en 2001

Neonatal screening and management of biologically low-risk localized neuroblastoma

artículo científico

Neuroblastic and Schwannian stromal cells of neuroblastoma are derived from a tumoral progenitor cell.

artículo científico publicado en 2001

Neuroblastoma

scientific article published on 01 April 1988

Neuroblastoma and treatment-related myelodysplasia/leukemia: the Memorial Sloan-Kettering experience and a literature review

artículo científico publicado en 1998

Neuroblastoma in adolescents and adults: the Memorial Sloan-Kettering experience

artículo científico publicado en 2003

Neuroblastoma metastatic to the central nervous system. The Memorial Sloan-kettering Cancer Center Experience and A Literature Review

artículo científico publicado en 2001

Neuroblastoma--from genetic profiles to clinical challenge

scientific article published on 01 November 2005

Neuroblastoma--linking a common allele to a rare disease

artículo científico publicado en 2008

Neuroblastoma: Therapeutic strategies for a clinical enigma

artículo científico publicado en 2010

Neuroblastoma: developmental biology, cancer genomics and immunotherapy

artículo científico publicado en 2013

Novel markers of subclinical disease for Ewing family tumors from gene expression profiling

artículo científico publicado en 2007

Novel regions of allelic imbalance identified by genome-wide analysis of neuroblastoma

scientific article published on 01 March 2002

Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults

artículo científico publicado en 2016

Oral (1-->3),(1-->4)-beta-D-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma

scientific article published on 01 May 2002

Oral etoposide for refractory and relapsed neuroblastoma.

artículo científico publicado en 1999

Oral topotecan for refractory and relapsed neuroblastoma: a retrospective analysis

artículo científico publicado en 2003

Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies

artículo científico publicado en 2002

Osteochondroma in long-term survivors of high-risk neuroblastoma

artículo científico publicado en 2015

Ototoxicity from high-dose use of platinum compounds in patients with neuroblastoma

artículo científico publicado en 2006

Overcoming leukemia heterogeneity by combining T cell engaging bispecific antibodies

scientific article published on 01 November 2020

Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody

artículo científico publicado en 2017

PDCT-04. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

scientific article published on 14 October 2020

Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.

artículo científico publicado en 2002

Pharmacokinetics and acute toxicology of intraventricular 131 I-monoclonal antibody targeting disialoganglioside in non-human primates

artículo científico publicado el 1 de noviembre de 1997

Pharmacokinetics, dosimetry, and toxicity of the targetable atomic generator, 225Ac-HuM195, in nonhuman primates

artículo científico publicado en 2004

Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8.

artículo científico publicado en 2007

Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission

artículo científico publicado en 2014

Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival.

artículo científico publicado en 2017

Phase II Trial of the Anti-GD2Monoclonal Antibody 3F8 and Granulocyte-Macrophage Colony-Stimulating Factor for Neuroblastoma ⬇️

artículo científico publicado el 15 de noviembre de 2001

Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors.

artículo científico publicado en 2000

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma

artículo científico publicado en 2011

Positional gene expression analysis identifies 12q overexpression and amplification in a subset of neuroblastomas

scientific article published on 01 October 2004

Posterior reversible encephalopathy syndrome in neuroblastoma patients receiving anti-GD2 3F8 monoclonal antibody

artículo científico publicado en 2013

Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using an IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex

artículo científico publicado en 2014

Preferential amplification of the paternal allele in neuroblastomas with N-myc amplification

scientific article published on 01 January 1994

Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas

artículo científico publicado en 1993

Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections

artículo científico publicado en 2010

Prognostic significance of GAGE detection in bone marrows on survival of patients with metastatic neuroblastoma

artículo científico publicado en 2000

Prognostic significance ofEPHB6, EFNB2, andEFNB3 expressions in neuroblastoma

artículo científico publicado en 2000

Prognostic value of MYCN and ID2 overexpression in neuroblastoma.

artículo científico publicado en 2005

Prognostic value of TrkA protein detection by monoclonal antibody 5C3 in neuroblastoma

artículo científico publicado en 1996

Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-GD2 immunotherapy and isotretinoin: a prospective Phase II study

artículo científico publicado en 2015

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome

artículo científico publicado en 2008

Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma

artículo científico publicado en 2003

Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8

scientific article published on 01 June 2002

Quantitation of marrow disease in neuroblastoma by real-time reverse transcription-PCR.

artículo científico publicado en 2001

Quantitative imaging of I-124 using positron emission tomography with applications to radioimmunodiagnosis and radioimmunotherapy

artículo científico publicado en 1991

Quantitative studies of monoclonal antibody targeting to disialoganglioside GD2 in human brain tumors

scientific article published on 01 May 1995

ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy ⬇️

artículo científico publicado el 18 de abril de 2012

Radiation Therapy to Sites of Metastatic Disease as Part of Consolidation in High-Risk Neuroblastoma: Can Long-term Control Be Achieved?

artículo científico publicado en 2018

Radically different treatment recommendations for newly diagnosed neuroblastoma: pitfalls in assessment of risk.

artículo científico publicado en 2004

Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities

artículo científico publicado en 1991

Radioimmunotargeting of human rhabdomyosarcoma using monoclonal antibody 8H9.

artículo científico publicado en 2005

Radioimmunotherapy of human tumours

artículo científico publicado en 2015

Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further process

artículo científico publicado en 2003

Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide

artículo científico publicado en 2008

Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases

artículo científico publicado en 2013

Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma

artículo científico publicado en 2009

Reduced-Dose Radiation Therapy to the Primary Site is Effective for High-Risk Neuroblastoma: Results From a Prospective Trial

scientific article published on 11 February 2019

Reduced-dose craniospinal irradiation for central nervous system relapsed neuroblastoma

artículo científico publicado en 2020

Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma

artículo científico publicado en 2004

Reply to L. Moreno et al ⬇️

artículo científico publicado el 10 de febrero de 2013

Resectability and operative morbidity after chemotherapy in neuroblastoma patients with encasement of major visceral arteries

scientific article published on 01 January 2011

Retargeting T cells to GD2 pentasaccharide on human tumors using Bispecific humanized antibody

artículo científico publicado en 2014

Rethinking management of localized neuroblastoma

scientific article published on 01 September 1993

Risks outweighed benefits from local radiation for non-stage 4 neuroblastoma

artículo científico publicado en 2002

Rituximab therapy of lymphoma is enhanced by orally administered (1-->3),(1-->4)-D-beta-glucan

artículo científico publicado en 2005

Role of low-affinity Fc receptors in antibody-dependent tumor cell phagocytosis by human monocyte-derived macrophages.

artículo científico publicado en 1991

SCDT-38. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma.

artículo científico publicado en 2009

Should we replace bone scintigraphy plus CT with MR imaging for staging of neuroblastoma?

artículo científico publicado en 2003

Sialyltransferase STX (ST8SiaII): a novel molecular marker of metastatic neuroblastoma

artículo científico publicado en 2006

Silencing Fc Domains in T cell-Engaging Bispecific Antibodies Improves T-cell Trafficking and Antitumor Potency

scientific article published on 15 October 2019

Single-chain Fv-streptavidin substantially improved therapeutic index in multistep targeting directed at disialoganglioside GD2.

artículo científico publicado en 2004

Solitary relapse of desmoplastic small round cell tumor detected by positron emission tomography/computed tomography

artículo científico publicado en 2008

Specific gene expression profiles and chromosomal abnormalities are associated with infant disseminated neuroblastoma

artículo científico publicado en 2009

Stage 4 neuroblastoma diagnosed at more than 1 year of age: gross total resection and clinical outcome

artículo científico publicado en 1994

Stage IV neuroblastoma more than 1 year of age at diagnosis: major response to chemotherapy and survival durations correlated strongly with dose intensity

scientific article published on 01 January 1991

Striking dichotomy in outcome of MYCN-amplified neuroblastoma in the contemporary era.

artículo científico publicado en 2014

Structural design of disialoganglioside GD2 and CD3-bispecific antibodies to redirect T cells for tumor therapy

artículo científico publicado en 2014

Structure Based Refinement of a Humanized Monoclonal Antibody That Targets Tumor Antigen Disialoganglioside GD2.

artículo científico publicado en 2014

Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors

artículo científico publicado en 2016

Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study.

artículo científico publicado en 2011

Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma with Prior Disease Progression

artículo científico publicado en 2020

Survival analysis of clinical, pathologic, and genetic features in neuroblastoma presenting as locoregional disease.

artículo científico publicado en 2001

Survival from locally invasive or widespread neuroblastoma without cytotoxic therapy

artículo científico publicado en 1996

Survival from non-stage 4 neuroblastoma without cytotoxic therapy: an analysis of clinical and biological markers ⬇️

artículo científico publicado el 1 de octubre de 1997

Synovial sarcoma mimicking desmoplastic small round-cell tumor: critical role for molecular diagnosis

artículo científico publicado en 1999

TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies

artículo científico publicado en 2018

THER-24. TARGETED RADIOIMMUNOTHERAPY FOR EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES

artículo científico publicado en 2019

Targeted radioimmunotherapy for embryonal tumor with multilayered rosettes

artículo científico publicado en 2019

Targeted radioimmunotherapy for leptomeningeal cancer using (131)I-3F8.

artículo científico publicado en 2000

Targeted radiotherapy and immunotherapy of human neuroblastoma with GD2 specific monoclonal antibodies

artículo científico publicado en 1989

Targeting Intracellular Antigens with pMHC-Binding Antibodies: A Phage Display Approach

artículo científico publicado en 2018

Technical challenges associated with the radiolabeling of monoclonal antibodies utilizing short-lived, positron emitting radionuclides

artículo científico publicado en 1991

Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma

The MYCN enigma: significance of MYCN expression in neuroblastoma

artículo científico publicado en 2006

The RET oncogene is a critical component of transcriptional programs associated with retinoic acid-induced differentiation in neuroblastoma

artículo científico publicado en 2007

The impact of gross total resection on local control and survival in high-risk neuroblastoma

artículo científico publicado en 2004

The potential of theragnostic ¹²⁴I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma

artículo científico publicado en 2014

Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates.

artículo científico publicado en 2015

Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma

Topotecan combined with myeloablative doses of thiotepa and carboplatin for neuroblastoma, brain tumors, and other poor-risk solid tumors in children and young adults

artículo científico publicado en 2001

Transient sialoadenitis: a complication of 131I-metaiodobenzylguanidine therapy

artículo científico publicado en 2008

Treatment and outcome of adult-onset neuroblastoma.

artículo científico publicado en 2018

Treatment of neuroblastoma meningeal carcinomatosis with intrathecal application of alpha-emitting atomic nanogenerators targeting disialo-ganglioside GD2.

artículo científico publicado en 2004

Treatment of spinal involvement in neuroblastoma patients.

artículo científico publicado en 2003

Treatment reduction for neuroblastoma

artículo científico publicado en 2004

Tumor lysis syndrome, neuroblastoma, and correlation between serum lactate dehydrogenase levels and MYCN-amplification

artículo científico publicado en 2003

Two-compartment model of radioimmunotherapy delivered through cerebrospinal fluid ⬇️

artículo científico publicado el 9 de octubre de 2010

Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment

artículo científico publicado en 2012

What factors predict a favorable outcome in young children with disseminated neuroblastoma?

artículo científico publicado en 2006

When overall survival fails to confirm event-free survival, should the latter be used to set the standard of care?

artículo científico publicado en 2014

Whole neuraxis irradiation to address central nervous system relapse in high-risk neuroblastoma

artículo científico publicado en 2010

Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma.

artículo científico publicado en 2007

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