Lista de obras -

A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring

artículo científico publicado en 2016

A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis

artículo científico publicado en 2016

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis

scientific journal article

A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

artículo científico publicado en 2018

A dermal niche for multipotent adult skin-derived precursor cells.

artículo científico publicado en 2004

A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.

artículo científico publicado en 2017

A novel neurofibromin (NF1) interaction with the leucine‐rich pentatricopeptide repeat motif‐containing protein links neurofibromatosis type 1 and the french canadian variant of leigh's syndrome in a common molecular complex ⬇️

artículo científico publicado el 30 de enero de 2013

A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines.

artículo científico publicado en 2013

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

artículo científico publicado en 2018

AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans

artículo científico publicado en 2007

APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

artículo científico publicado en 2006

ATPS-28COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS.

artículo científico publicado en 2015

Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration

scientific article published on 02 January 2020

An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells.

artículo científico publicado en 2012

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program

scientific journal article

An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth

scientific journal article

Analysis of the neurogenic potential of multipotent skin-derived precursors

artículo científico publicado en 2006

Ankrd11 is a chromatin regulator involved in autism that is essential for neural development

artículo científico

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma.

artículo científico publicado en 2014

Axon growth inhibition: signals from the p75 neurotrophin receptor ⬇️

artículo científico publicado el 1 de mayo de 2003

BMI1 is a therapeutic target in recurrent medulloblastoma

artículo científico publicado en 2018

BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM.

artículo científico publicado en 2014

Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3'-kinase pathway.

artículo científico publicado en 2002

CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain

artículo científico publicado en 2010

CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development

artículo científico publicado en 2013

CCM2 mediates death signaling by the TrkA receptor tyrosine kinase

artículo científico publicado en 2009

COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS.

artículo científico publicado en 2014

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

artículo científico publicado en 2003

Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis

artículo científico publicado en 2010

Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments

scientific article published on 30 August 2019

Conditional ablation of p63 indicates that it is essential for embryonic development of the central nervous system

artículo científico publicado en 2015

Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome

artículo científico publicado en 2007

Costello syndrome H-Ras alleles regulate cortical development

artículo científico publicado en 2009

Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma

artículo científico publicado en 2018

Dedifferentiated Schwann Cell Precursors Secreting Paracrine Factors Are Required for Regeneration of the Mammalian Digit Tip.

artículo científico publicado en 2016

Developing with BDNF: a moving experience

artículo científico publicado en 2007

Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling

artículo científico publicado en 2017

Direct genesis of functional rodent and human schwann cells from skin mesenchymal precursors

artículo científico publicado en 2014

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

artículo científico publicado en 2016

Endogenous microglia regulate development of embryonic cortical precursor cells

artículo científico publicado en 2011

Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.

artículo científico publicado en 2005

FoxP2 Regulates Neurogenesis during Embryonic Cortical Development ⬇️

artículo científico publicado el 2 de enero de 2013

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

artículo científico publicado en 2020

HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

scientific article published on 16 September 2009

High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model

artículo científico publicado en 2006

Identification of Drugs that Regulate Dermal Stem Cells and Enhance Skin Repair.

artículo científico publicado en 2015

In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model

artículo científico publicado en 2009

Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma

article by Risa Torkin et al published 1 January 2005 in Molecular Cancer Therapeutics

Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development.

artículo científico publicado en 2018

Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

artículo científico publicado en 2010

LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

scientific article published on 01 October 2020

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

scientific journal article

Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration

artículo científico publicado en 2018

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation

artículo científico publicado en 2015

Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation

artículo científico publicado en 2012

Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells

scientific article published on 24 April 2020

Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype

artículo científico publicado en 2008

Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain

artículo científico publicado en 2017

Mobilizing Endogenous Stem Cells for Repair and Regeneration: Are We There Yet? ⬇️

artículo científico publicado el 14 de junio de 2012

N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons.

artículo científico publicado en 2002

Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition

artículo científico publicado en 2011

Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell

artículo científico publicado en 2007

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes

artículo científico publicado en 2013

Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex

artículo científico publicado en 2014

Neuronal MEK is important for normal fear conditioning in mice.

artículo científico publicado en 2004

Peripheral Nerve Single Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth

artículo científico publicado en 2020

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

artículo científico publicado en 2013

Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks

artículo científico publicado en 2016

RNAi screen identifies essential regulators of human brain metastasis-initiating cells.

artículo científico publicado en 2017

SATB2 augments ΔNp63α in head and neck squamous cell carcinoma

artículo científico publicado en 2010

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

artículo científico publicado en 2010

Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse.

artículo científico publicado en 2003

Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis

scientific article published on 01 August 2020

Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair

artículo científico publicado en 2009

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells.

artículo científico publicado en 2016

Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells

artículo científico publicado en 2011

Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development

artículo científico publicado en 2014

Sox2-mediated regulation of adult neural crest precursors and skin repair

artículo científico publicado en 2013

Special AT-rich Binding Protein-2 (SATB2) Differentially Affects Disease-causing p63 Mutant Proteins ⬇️

artículo científico publicado el 29 de septiembre de 2011

Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes.

artículo científico publicado en 2002

System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.

artículo científico publicado en 2010

TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors.

artículo científico publicado en 2010

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

artículo científico publicado en 2008

The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis

scientific article published on 01 January 2020

The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life

artículo científico publicado en 2014

The invulnerability of adult neurons: a critical role for p73.

artículo científico publicado en 2004

To die or not to die: neurons and p63.

artículo científico publicado en 2007

Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway.

artículo científico publicado en 2013

Translating neural stem cells to neurons in the mammalian brain

artículo científico publicado en 2019

Trk signaling regulates neural precursor cell proliferation and differentiation during cortical development.

artículo científico publicado en 2007

TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism

artículo científico publicado en 2005

p63 Regulates adult neural precursor and newly born neuron survival to control hippocampal-dependent Behavior

artículo científico publicado en 2013

p63 antagonizes p53 to promote the survival of embryonic neural precursor cells

artículo científico publicado en 2009

p63 is an essential proapoptotic protein during neural development

scientific journal article

p73 haploinsufficiency causes tau hyperphosphorylation and tau kinase dysregulation in mouse models of aging and Alzheimer's disease

artículo científico publicado en 2012

p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease

artículo científico publicado en 2008

p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse

artículo científico publicado en 2010

p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

artículo científico publicado en 2010

Lista de obras de

A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring

A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis

A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

A dermal niche for multipotent adult skin-derived precursor cells.

A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.

A novel neurofibromin (NF1) interaction with the leucine‐rich pentatricopeptide repeat motif‐containing protein links neurofibromatosis type 1 and the french canadian variant of leigh's syndrome in a common molecular complex ⬇️

A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines.

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans

APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

ATPS-28COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS.

Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration

An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells.

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program

An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth

Analysis of the neurogenic potential of multipotent skin-derived precursors

Ankrd11 is a chromatin regulator involved in autism that is essential for neural development

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma.

Axon growth inhibition: signals from the p75 neurotrophin receptor ⬇️

BMI1 is a therapeutic target in recurrent medulloblastoma

BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM.

Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3'-kinase pathway.

CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain

CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development

CCM2 mediates death signaling by the TrkA receptor tyrosine kinase

COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS.

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis

Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments

Conditional ablation of p63 indicates that it is essential for embryonic development of the central nervous system

Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome

Costello syndrome H-Ras alleles regulate cortical development

Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma

Dedifferentiated Schwann Cell Precursors Secreting Paracrine Factors Are Required for Regeneration of the Mammalian Digit Tip.

Developing with BDNF: a moving experience

Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling

Direct genesis of functional rodent and human schwann cells from skin mesenchymal precursors

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

Endogenous microglia regulate development of embryonic cortical precursor cells

Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.

FoxP2 Regulates Neurogenesis during Embryonic Cortical Development ⬇️

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model

Identification of Drugs that Regulate Dermal Stem Cells and Enhance Skin Repair.

In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model

Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma

Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development.

Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation

Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation

Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells

Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype

Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain

Mobilizing Endogenous Stem Cells for Repair and Regeneration: Are We There Yet? ⬇️

N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons.

Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition

Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes

Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex

Neuronal MEK is important for normal fear conditioning in mice.

Peripheral Nerve Single Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks

RNAi screen identifies essential regulators of human brain metastasis-initiating cells.

SATB2 augments ΔNp63α in head and neck squamous cell carcinoma

Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse.

Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis

Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells.

Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells

Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development

Sox2-mediated regulation of adult neural crest precursors and skin repair

Special AT-rich Binding Protein-2 (SATB2) Differentially Affects Disease-causing p63 Mutant Proteins ⬇️