Lista de obras -

A mutational analysis of active site residues in trans‐3‐chloroacrylic acid dehalogenase ⬇️

artículo científico publicado el 10 de julio de 2013

Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N'-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1

artículo científico publicado en 2020

An Unexpected Promiscuous Activity of 4‐Oxalocrotonate Tautomerase: The cis–trans Isomerisation of Nitrostyrene ⬇️

artículo científico publicado el 31 de julio de 2012

Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion Intermediates

article

Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes

artículo científico publicado en 2013

Biochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxus

artículo científico publicado en 2013

Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to β‐Nitrostyrenes Catalyzed by a Promiscuous Proline‐Based Tautomerase ⬇️

artículo científico publicado el 21 de diciembre de 2011

Catalytic Mechanisms and Biocatalytic Applications of Aspartate and Methylaspartate Ammonia Lyases ⬇️

artículo científico publicado el 16 de agosto de 2012

Characterization of a Newly Identified Mycobacterial Tautomerase with Promiscuous Dehalogenase and Hydratase Activities Reveals a Functional Link to a Recently Diverged cis-3-Chloroacrylic Acid Dehalogenase ⬇️

artículo científico publicado el 22 de marzo de 2011

Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans

artículo científico publicado en 2011

Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors.

artículo científico publicado en 2018

Dehalogenation of an Anthropogenic Compound by an Engineered Variant of the Mouse Cytokine Macrophage Migration Inhibitory Factor ⬇️

artículo científico publicado el 21 de mayo de 2012

Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase

artículo científico publicado en 2014

Discovery of an Escherichia coli Esterase with High Activity and Enantioselectivity toward 1,2- O -Isopropylideneglycerol Esters ⬇️

artículo científico publicado el 15 de julio de 2011

Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.

artículo científico publicado en 2017

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

artículo científico publicado en 2019

Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

scientific article published on 19 November 2019

Engineering a Promiscuous Tautomerase into a More Efficient Aldolase for Self-Condensations of Linear Aliphatic Aldehydes

artículo científico publicado en 2017

Enhancement of the Promiscuous Aldolase and Dehydration Activities of 4‐Oxalocrotonate Tautomerase by Protein Engineering ⬇️

artículo científico publicado el 21 de mayo de 2012

Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives

artículo científico publicado en 2009

Evidence for the formation of an enamine species during aldol and Michael-type addition reactions promiscuously catalyzed by 4-oxalocrotonate tautomerase

artículo científico publicado en 2015

Facilitated Drug Influx by an Energy-uncoupled Secondary Multidrug Transporter ⬇️

artículo científico publicado el 14 de octubre de 2003

In Situ Acetaldehyde Synthesis for Carboligation Reactions

artículo científico publicado en 2019

Inter- and intramolecular aldol reactions promiscuously catalyzed by a proline-based tautomerase

artículo científico publicado en 2017

Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities ⬇️

artículo científico publicado el 2 de julio de 2013

Metabolic alkene labeling and in vitro detection of histone acylation via the aqueous oxidative Heck reaction

artículo científico publicado en 2015

Modular Enzymatic Cascade Synthesis of Vitamin B5 and Its Derivatives

scientific article published on 30 October 2018

Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4-Oxalocrotonate Tautomerase More Effectively than Distant Mutations.

artículo científico publicado en 2016

Photoaffinity labeling under non-energized conditions of a specific drug-binding site of the ABC multidrug transporter LmrA from Lactococcus lactis ⬇️

artículo científico publicado el 21 de noviembre de 2003

Promiscuous Catalysis of Asymmetric Michael‐Type Additions of Linear Aldehydes to β‐Nitrostyrene by the Proline‐Based Enzyme 4‐Oxalocrotonate Tautomerase ⬇️

artículo científico publicado el 9 de enero de 2013

Recent Advances in the Study of Enzyme Promiscuity in the Tautomerase Superfamily ⬇️

artículo científico publicado el 3 de mayo de 2013

Stereochemical Control of Enzymatic Carbon-Carbon Bond-Forming Michael-Type Additions by "Substrate Engineering".

artículo científico publicado en 2016

Structural Basis for the Catalytic Mechanism of Ethylenediamine- N, N'-disuccinic Acid Lyase, a Carbon-Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope.

artículo científico publicado en 2018

Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF)

artículo científico publicado en 2019

Systematic Screening for Catalytic Promiscuity in 4‐Oxalocrotonate Tautomerase: Enamine Formation and Aldolase Activity ⬇️

artículo científico publicado el 3 de febrero de 2011

The Lactococcal lmrP Gene Encodes a Proton Motive Force- dependent Drug Transporter ⬇️

artículo científico publicado el 3 de noviembre de 1995

The roles of active site residues in the catalytic mechanism of methylaspartate ammonia‐lyase ⬇️

artículo científico publicado el 8 de julio de 2013

Tuning Enzyme Activity for Nonaqueous Solvents: Engineering an Enantioselective "Michaelase" for Catalysis in High Concentrations of Ethanol

artículo científico publicado en 2019

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

artículo científico publicado en 2016

Lista de obras de

A mutational analysis of active site residues in trans‐3‐chloroacrylic acid dehalogenase ⬇️

Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N'-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1

An Unexpected Promiscuous Activity of 4‐Oxalocrotonate Tautomerase: The cis–trans Isomerisation of Nitrostyrene ⬇️

Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion Intermediates

Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes

Biochemical Properties and Crystal Structure of a -Phenylalanine Aminotransferase from Variovorax paradoxus

Bridging between Organocatalysis and Biocatalysis: Asymmetric Addition of Acetaldehyde to β‐Nitrostyrenes Catalyzed by a Promiscuous Proline‐Based Tautomerase ⬇️

Catalytic Mechanisms and Biocatalytic Applications of Aspartate and Methylaspartate Ammonia Lyases ⬇️

Characterization of a Newly Identified Mycobacterial Tautomerase with Promiscuous Dehalogenase and Hydratase Activities Reveals a Functional Link to a Recently Diverged cis-3-Chloroacrylic Acid Dehalogenase ⬇️

Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans

Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors.

Dehalogenation of an Anthropogenic Compound by an Engineered Variant of the Mouse Cytokine Macrophage Migration Inhibitory Factor ⬇️

Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase

Discovery of an Escherichia coli Esterase with High Activity and Enantioselectivity toward 1,2- O -Isopropylideneglycerol Esters ⬇️

Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

Engineering a Promiscuous Tautomerase into a More Efficient Aldolase for Self-Condensations of Linear Aliphatic Aldehydes

Enhancement of the Promiscuous Aldolase and Dehydration Activities of 4‐Oxalocrotonate Tautomerase by Protein Engineering ⬇️

Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives

Evidence for the formation of an enamine species during aldol and Michael-type addition reactions promiscuously catalyzed by 4-oxalocrotonate tautomerase

Facilitated Drug Influx by an Energy-uncoupled Secondary Multidrug Transporter ⬇️

In Situ Acetaldehyde Synthesis for Carboligation Reactions

Inter- and intramolecular aldol reactions promiscuously catalyzed by a proline-based tautomerase

Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities ⬇️

Metabolic alkene labeling and in vitro detection of histone acylation via the aqueous oxidative Heck reaction

Modular Enzymatic Cascade Synthesis of Vitamin B5 and Its Derivatives

Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4-Oxalocrotonate Tautomerase More Effectively than Distant Mutations.

Photoaffinity labeling under non-energized conditions of a specific drug-binding site of the ABC multidrug transporter LmrA from Lactococcus lactis ⬇️

Promiscuous Catalysis of Asymmetric Michael‐Type Additions of Linear Aldehydes to β‐Nitrostyrene by the Proline‐Based Enzyme 4‐Oxalocrotonate Tautomerase ⬇️

Recent Advances in the Study of Enzyme Promiscuity in the Tautomerase Superfamily ⬇️

Stereochemical Control of Enzymatic Carbon-Carbon Bond-Forming Michael-Type Additions by "Substrate Engineering".

Structural Basis for the Catalytic Mechanism of Ethylenediamine- N, N'-disuccinic Acid Lyase, a Carbon-Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope.

Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF)

Systematic Screening for Catalytic Promiscuity in 4‐Oxalocrotonate Tautomerase: Enamine Formation and Aldolase Activity ⬇️

The Lactococcal lmrP Gene Encodes a Proton Motive Force- dependent Drug Transporter ⬇️

The roles of active site residues in the catalytic mechanism of methylaspartate ammonia‐lyase ⬇️

Tuning Enzyme Activity for Nonaqueous Solvents: Engineering an Enantioselective "Michaelase" for Catalysis in High Concentrations of Ethanol

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases