Lista de obras -

(-)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata, Induces DNA Double-Strand Breaks

artículo científico publicado en 2017

A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity

scientific article published on 06 June 2016

A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium

artículo científico publicado en 2003

Acetophenone Monomers from Acronychia trifoliolata.

artículo científico publicado en 2016

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models

artículo científico publicado en 2014

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

artículo científico

An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis

artículo científico publicado en 2007

An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures

artículo científico publicado en 2020

Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines

artículo científico publicado en 2019

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model

artículo científico publicado en 2015

Antiproliferative Alkaloids from Alangium longiflorum, an Endangered Tropical Plant Species.

artículo científico publicado en 2018

Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus ⬇️

artículo científico publicado el 21 de mayo de 2013

Antiviral lectins: Selective inhibitors of viral entry

artículo científico publicado en 2017

Atomic-resolution crystal structure of the antiviral lectin scytovirin

artículo científico publicado en 2007

Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site

artículo científico publicado en 2011

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

artículo científico publicado en 2010

Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae

artículo científico publicado en 2010

CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells

artículo científico publicado en 2020

Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses

artículo científico publicado en 2021

Correction to Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)–Topoisomerase I (Top1) Inhibitors ⬇️

artículo científico publicado el 14 de agosto de 2012

Corymbulosins D-H, 2-Hydroxy- and 2-Oxo-clerodane Diterpenes from the Bark of Laetia corymbulosa

artículo científico publicado en 2017

Corymbulosins I-W, Cytotoxic Clerodane Diterpenes from the Bark of Laetia corymbulosa.

artículo científico publicado en 2017

Creating and screening natural product libraries

artículo científico publicado en 2020

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine

artículo científico publicado en 2007

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

artículo científico publicado en 2007

Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus

artículo científico publicado en 2003

Cyclonellin, a new cyclic octapeptide from the marine sponge Axinella carteri

artículo científico publicado en 2004

Cytotoxic Metabolites from an Australian Collection of the SpongeJaspisSpecies

artículo científico publicado en 2002

Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.

artículo científico publicado en 2002

Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma

scientific article published on 27 August 2004

Differential inhibitory effects of cyanovirin-N, griffithsin, and scytovirin on entry mediated by envelopes of gammaretroviruses and deltaretroviruses

artículo científico publicado en 2013

Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor

artículo científico publicado en 2015

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53. ⬇️

scientific article published on 14 October 2008

Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.

artículo científico publicado en 2006

Encoded Fiber‐Optic Microsphere Arrays for Probing Protein–Carbohydrate Interactions ⬇️

artículo científico publicado el 10 de noviembre de 2003

Engineering DNA topology with locked nucleosides: a structural study

artículo científico publicado en 2005

Engineering soya bean seeds as a scalable platform to produce cyanovirin-N, a non-ARV microbicide against HIV

artículo científico publicado en 2015

Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens

artículo científico publicado en 2018

Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana

scientific article published on 10 April 2018

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

scientific article published on 10 February 2020

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

artículo científico publicado en 2015

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

artículo científico publicado en 2018

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

artículo científico publicado en 2015

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

artículo científico publicado en 2020

Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta

scientific article published on 29 November 2018

High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41.

artículo científico publicado en 2002

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

article published in 2017

Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays

artículo científico publicado en 2014

Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen

artículo científico publicado en 2008

India-United States Dialogue on Traditional Medicine: Toward Collaborative Research and Generation of an Evidence Base.

artículo científico publicado en 2018

Influenza A (H1N1) virus resistance to cyanovirin-N arises naturally during adaptation to mice and by passage in cell culture in the presence of the inhibitor

artículo científico publicado en 2007

Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate

artículo científico publicado en 2011

Isolation and characterization of anti-HIV peptides from Dorstenia contrajerva and Treculia obovoidea

artículo científico publicado en 2004

Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

artículo científico publicado en 2005

Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Hernandia nymphaeifolia

artículo científico publicado en 2019

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

artículo científico publicado en 2017

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

artículo científico publicado en 2010

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

artículo científico publicado en 2013

Molecular Genomic Features Associated with in Vitro Response of the NCI-60 Cancer Cell Line Panel to Natural Products

artículo científico publicado en 2020

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

artículo científico publicado en 2010

Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization

artículo científico publicado en 2002

NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening

artículo científico publicado en 2018

NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp

scientific article published on 04 August 2019

National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

artículo científico publicado en 2020

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions

artículo científico publicado en 2004

Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium

artículo científico publicado en 2005

Potent anti-HIV activity of scytovirin domain 1 peptide.

artículo científico publicado en 2006

Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin

artículo científico publicado en 2003

Prenylated Acetophloroglucinol Dimers from Acronychia trifoliolata: Structure Elucidation and Total Synthesis

artículo científico publicado en 2019

Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides

artículo científico

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I

artículo científico publicado en 2020

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

artículo científico publicado en 2005

Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

scientific article published on 20 January 2022

Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV.

artículo científico publicado en 2016

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea ⬇️

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

artículo científico publicado en 2009

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities

scientific article published on 02 January 2019

Secondary Metabolites, Monoterpene-Polyketides Containing a Spiro[3.5]nonane from Cryptocarya laevigata.

artículo científico publicado en 2018

Spiro[3.5]nonenyl Meroterpenoid Lactones, Cryptolaevilactones G-L, an Ionone Derivative, and Total Synthesis of Cryptolaevilactone M from Cryptocarya laevigata

scientific article published on 23 August 2019

Stable Vindoline Production in Transformed Cell Cultures ofCatharanthus roseus

artículo científico publicado en 2002

Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods

artículo científico publicado en 2020

Structure of a lectin from the sea mussel Crenomytilus grayanus (CGL).

artículo científico publicado en 2015

Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.

artículo científico publicado en 2010

Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides

artículo científico publicado en 2002

Suberitamides A-C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity

scientific article published on 28 October 2020

Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii

artículo científico publicado en 2009

Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)–Topoisomerase I (Top1) Inhibitors ⬇️

artículo científico publicado el 26 de abril de 2012

Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas

scientific article published on 17 December 2019

The NCI library of traditional Chinese medicinal plant extracts - Preliminary assessment of the NCI-60 activity and chemical profiling of selected species

scientific article published on 03 August 2019

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

scientific article published on 30 May 2019

The Novel Fold of Scytovirin Reveals a New Twist For Antiviral Entry Inhibitors

artículo científico publicado en 2007

The antiretroviral lectin cyanovirin-N targets well-known and novel targets on the surface of Entamoeba histolytica trophozoites

artículo científico publicado en 2010

The canSAR data hub for drug discovery.

artículo científico publicado en 2016

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus

artículo científico publicado en 2014

The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures

artículo científico publicado en 2002

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells

artículo científico publicado en 2011

Topology of the disulfide bonds in the antiviral lectin scytovirin

artículo científico publicado en 2010

Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N.

artículo científico publicado en 2008

Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea

scientific article published on 10 July 2020

US National Cancer Institute-China Collaborative Studies on Chinese Medicine and Cancer.

artículo científico publicado en 2017

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.

artículo científico publicado en 2014

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm

article published in the Proceedings of the National Academy of Sciences of the United States of America

Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris

artículo científico publicado en 2020

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity

artículo científico publicado en 2008

Lista de obras de

(-)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata, Induces DNA Double-Strand Breaks

A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity

A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium

Acetophenone Monomers from Acronychia trifoliolata.

Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis

An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures

Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model

Antiproliferative Alkaloids from Alangium longiflorum, an Endangered Tropical Plant Species.

Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus ⬇️

Antiviral lectins: Selective inhibitors of viral entry

Atomic-resolution crystal structure of the antiviral lectin scytovirin

Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae

CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells

Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses

Correction to Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)–Topoisomerase I (Top1) Inhibitors ⬇️

Corymbulosins D-H, 2-Hydroxy- and 2-Oxo-clerodane Diterpenes from the Bark of Laetia corymbulosa

Corymbulosins I-W, Cytotoxic Clerodane Diterpenes from the Bark of Laetia corymbulosa.

Creating and screening natural product libraries

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus

Cyclonellin, a new cyclic octapeptide from the marine sponge Axinella carteri

Cytotoxic Metabolites from an Australian Collection of the SpongeJaspisSpecies

Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.

Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma

Differential inhibitory effects of cyanovirin-N, griffithsin, and scytovirin on entry mediated by envelopes of gammaretroviruses and deltaretroviruses

Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53. ⬇️

Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.

Encoded Fiber‐Optic Microsphere Arrays for Probing Protein–Carbohydrate Interactions ⬇️

Engineering DNA topology with locked nucleosides: a structural study

Engineering soya bean seeds as a scalable platform to produce cyanovirin-N, a non-ARV microbicide against HIV

Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens

Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture

Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta

High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41.

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays

Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen

India-United States Dialogue on Traditional Medicine: Toward Collaborative Research and Generation of an Evidence Base.

Influenza A (H1N1) virus resistance to cyanovirin-N arises naturally during adaptation to mice and by passage in cell culture in the presence of the inhibitor

Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate

Isolation and characterization of anti-HIV peptides from Dorstenia contrajerva and Treculia obovoidea

Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Hernandia nymphaeifolia

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

Molecular Genomic Features Associated with in Vitro Response of the NCI-60 Cancer Cell Line Panel to Natural Products

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization

NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening

NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp

National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions

Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium

Potent anti-HIV activity of scytovirin domain 1 peptide.

Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin

Prenylated Acetophloroglucinol Dimers from Acronychia trifoliolata: Structure Elucidation and Total Synthesis

Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV.

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea ⬇️

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities

Secondary Metabolites, Monoterpene-Polyketides Containing a Spiro[3.5]nonane from Cryptocarya laevigata.

Spiro[3.5]nonenyl Meroterpenoid Lactones, Cryptolaevilactones G-L, an Ionone Derivative, and Total Synthesis of Cryptolaevilactone M from Cryptocarya laevigata