Lista de obras -

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

artículo científico publicado en 2016

A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis

artículo científico publicado en 2000

A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages

artículo científico publicado en 2005

A mix-and-measure assay for determining the activation status of endogenous Cdc42 in cytokine-stimulated macrophage cell lysates

artículo científico publicado en 2014

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging

artículo científico publicado en 2014

A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism

artículo científico publicado en 2011

A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18)

artículo científico publicado en 2001

A requirement for ARF6 in Fcgamma receptor-mediated phagocytosis in macrophages

artículo científico publicado en 1998

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

artículo científico publicado en 1999

An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction

artículo científico publicado en 2014

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.

artículo científico publicado en 2016

Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.

artículo científico publicado en 2009

Characterization of Genetically Encoded FRET Biosensors for Rho-Family GTPases.

artículo científico publicado en 2018

Chemotactic responses by macrophages to a directional source of a cytokine delivered by a micropipette

artículo científico publicado en 2014

Contribution of CXCL12 secretion to invasion of breast cancer cells.

artículo científico publicado en 2012

Exosomes and nanotubes: Control of immune cell communication

artículo científico publicado en 2015

Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

artículo científico publicado en 2004

Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton

artículo científico publicado en 2013

Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods

artículo científico publicado en 1995

High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors

artículo científico publicado en 2009

Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro

artículo científico publicado en 2012

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

artículo científico publicado en 2014

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

artículo científico publicado en 2005

Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

artículo científico publicado en 2008

Myosin X is a downstream effector of PI(3)K during phagocytosis

scientific journal article

N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis

artículo científico publicado en 2010

Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes

artículo científico publicado en 2010

Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.

artículo científico publicado en 2016

Phagocytic signaling strategies: Fc(gamma)receptor-mediated phagocytosis as a model system

artículo científico publicado en 2001

Phagocytosis inhibits F-actin-enriched membrane protrusions stimulated by fractalkine (CX3CL1) and colony-stimulating factor 1.

artículo científico publicado en 2009

Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion

artículo científico publicado en 2011

Rac1 and Cdc42 are required for phagocytosis, but not NF-kappaB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosa

article

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants

artículo científico publicado en 1996

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages

artículo científico publicado en 2009

Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis

scientific article published on 26 February 2011

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

artículo científico publicado en 1997

Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model

artículo científico publicado en 2001

Signaling networks regulating leukocyte podosome dynamics and function

artículo científico publicado en 2011

Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).

artículo científico publicado en 2005

Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophages

artículo científico publicado en 2011

Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

artículo científico publicado en 1996

Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.

artículo científico publicado en 2015

T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse

artículo científico publicado en 2003

Targeted disruption of the ABP-120 gene leads to cells with altered motility

artículo científico publicado en 1992

The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.

artículo científico publicado en 2009

The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

artículo científico publicado en 2017

The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions

artículo científico publicado en 2012

The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.

artículo científico publicado en 2009

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association

artículo científico publicado en 2011

The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts

artículo científico publicado en 2010

The non-redundant role of N-WASP in podosome-mediated matrix degradation in macrophages

artículo científico publicado en 2010

Tunneling nanotubes, a novel mode of tumor cell-macrophage communication in tumor cell invasion

scientific article published on 11 February 2019

Two-dimensional motility of a macrophage cell line on microcontact-printed fibronectin

artículo científico publicado en 2014

Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function

artículo científico publicado en 2014

Using Fluorescence Resonance Energy Transfer-Based Biosensors to Probe Rho GTPase Activation During Phagocytosis

artículo científico publicado en 2017

Visualization of actin polymerization in invasive structures of macrophages and carcinoma cells using photoconvertible β-actin-Dendra2 fusion proteins

artículo científico publicado en 2011

Western analysis of intracellular interleukin-8 in human mononuclear leukocytes

artículo científico publicado en 2014

Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis

artículo científico publicado en 2013

Lista de obras de

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis

A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages

A mix-and-measure assay for determining the activation status of endogenous Cdc42 in cytokine-stimulated macrophage cell lysates

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging

A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism

A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18)

A requirement for ARF6 in Fcgamma receptor-mediated phagocytosis in macrophages

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.

Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.

Characterization of Genetically Encoded FRET Biosensors for Rho-Family GTPases.

Chemotactic responses by macrophages to a directional source of a cytokine delivered by a micropipette

Contribution of CXCL12 secretion to invasion of breast cancer cells.

Exosomes and nanotubes: Control of immune cell communication

Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton

Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods

High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors

Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

Myosin X is a downstream effector of PI(3)K during phagocytosis

N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis

Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes

Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.

Phagocytic signaling strategies: Fc(gamma)receptor-mediated phagocytosis as a model system

Phagocytosis inhibits F-actin-enriched membrane protrusions stimulated by fractalkine (CX3CL1) and colony-stimulating factor 1.

Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion

Rac1 and Cdc42 are required for phagocytosis, but not NF-kappaB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosa

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages

Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model

Signaling networks regulating leukocyte podosome dynamics and function

Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).

Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophages

Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.

T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse

Targeted disruption of the ABP-120 gene leads to cells with altered motility

The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.

The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions

The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association

The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts

The non-redundant role of N-WASP in podosome-mediated matrix degradation in macrophages

Tunneling nanotubes, a novel mode of tumor cell-macrophage communication in tumor cell invasion

Two-dimensional motility of a macrophage cell line on microcontact-printed fibronectin

Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function

Using Fluorescence Resonance Energy Transfer-Based Biosensors to Probe Rho GTPase Activation During Phagocytosis

Visualization of actin polymerization in invasive structures of macrophages and carcinoma cells using photoconvertible β-actin-Dendra2 fusion proteins

Western analysis of intracellular interleukin-8 in human mononuclear leukocytes

Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis