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Lista de obras de Ralph Isberg

A 76-amino acid disulfide loop in the Yersinia pseudotuberculosis invasin protein is required for integrin receptor recognition

artículo científico publicado en 1993

A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death

artículo científico publicado en 2006

A Single Legionella Effector Catalyzes a Multistep Ubiquitination Pathway to Rearrange Tubular Endoplasmic Reticulum for Replication.

artículo científico publicado en 2016

A bifunctional bacterial protein links GDI displacement to Rab1 activation

artículo científico publicado en 2007

A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii.

artículo científico publicado en 2018

A hemidominant Naip5 allele in mouse strain MOLF/Ei-derived macrophages restricts Legionella pneumophila intracellular growth.

artículo científico publicado en 2008

A molecular strategy for the study of bacterial invasion

artículo científico publicado en 1987

A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association

artículo científico publicado en 1999

A region of the Yersinia pseudotuberculosis invasin protein that contributes to high affinity binding to integrin receptors

artículo científico publicado en 1996

A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12.

artículo científico publicado en 1985

Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability

artículo científico publicado en 2019

Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen ⬇️

artículo científico publicado el 14 de diciembre de 2012

Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene

artículo científico publicado en 1994

An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic

scholarly article by Jessica M Morgan et al published 2018 in Frontiers in cellular and infection microbiology

An O antigen can interfere with the function of the Yersinia pseudotuberculosis invasin protein ⬇️

artículo científico publicado el 1 de febrero de 1991

An aspartate residue of the Yersinia pseudotuberculosis invasin protein that is critical for integrin binding.

artículo científico publicado en 1995

An immunoglobulin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors

artículo científico publicado en 2000

An open letter to Elias Zerhouni

artículo científico publicado en 2005

Analysis of Legionella Infection Using RNAi in Drosophila Cells ⬇️

artículo científico publicado el 1 de enero de 2013

Analysis of expression and thermoregulation of the Yersinia pseudotuberculosis inv gene with hybrid proteins

artículo científico publicado en 1988

Analysis of the Legionella pneumophila fliI gene: intracellular growth of a defined mutant defective for flagellum biosynthesis

artículo científico publicado en 1997

Analysis of the intracellular fate of Legionella pneumophila mutants

artículo científico

Analysis of the role of invasin during Yersinia pseudotuberculosis infection of mice

artículo científico publicado en 1996

Analyzing microbial disease at high resolution: following the fate of the bacterium during infection ⬇️

artículo científico publicado el 3 de diciembre de 2011

Antibiotic modulation of capsular exopolysaccharide and virulence in Acinetobacter baumannii

artículo científico publicado en 2015

Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

scientific article published on 09 September 2020

Arf6 and phosphoinositol-4-phosphate-5-kinase activities permit bypass of the Rac1 requirement for beta1 integrin-mediated bacterial uptake

artículo científico publicado en 2003

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

artículo científico publicado en 1995

Author Correction: Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

artículo científico publicado en 2020

Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density

artículo científico publicado en 1993

Bacterial pathogen manipulation of host membrane trafficking

artículo científico

Binding and internalization of microorganisms by integrin receptors

artículo científico publicado en 1994

Binding of cultured mammalian cells to immobilized bacteria ⬇️

artículo científico publicado el 1 de febrero de 1992

Border patrols and secret passageways across the intestinal epithelium

artículo científico publicado en 2000

CD8(+) T cells restrict Yersinia pseudotuberculosis infection: bypass of anti-phagocytosis by targeting antigen-presenting cells

artículo científico publicado en 2009

CD8(+) T cells specific to a single Yersinia pseudotuberculosis epitope restrict bacterial replication in the liver but fail to provide sterilizing immunity

artículo científico publicado en 2016

Cdc42 interacts with the exocyst complex to promote phagocytosis ⬇️

artículo científico publicado el 7 de enero de 2013

Cell biology of Legionella pneumophila

artículo científico publicado en 1999

Cellular internalization in the absence of invasin expression is promoted by the Yersinia pseudotuberculosis yadA product

artículo científico publicado en 1993

Common entry mechanisms. Bacterial pathogenesis

artículo científico publicado en 1996

Community behavior and spatial regulation within a bacterial microcolony in deep tissue sites serves to protect against host attack

artículo científico publicado en 2014

Comparison of the ability of enteroinvasive Escherichia coli, Salmonella typhimurium, Yersinia pseudotuberculosis, and Yersinia enterocolitica to enter and replicate within HEp-2 cells

artículo científico publicado en 1987

Compartmentalization of the proteins encoded by IS50R

scientific article published on 01 March 1985

Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole

artículo científico publicado en 2020

Conferral of transposable properties to a chromosomal gene in Escherichia coli ⬇️

artículo científico publicado el 15 de agosto de 1980

Conjugative Transfer by the Virulence System of Legionella pneumophila ⬇️

artículo científico publicado el 6 de febrero de 1998

Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses.

artículo científico publicado en 2018

Control of host cell phosphorylation by legionella pneumophila

artículo científico publicado en 2011

Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: Analysis using platelet-derived growth factor and platelet-poor plasma ⬇️

artículo científico publicado el 1 de junio de 1979

Correction for Amyot et al., Poison Domains Block Transit of Translocated Substrates via the Legionella pneumophila Icm/Dot System.

artículo científico publicado en 2014

Crystal structure of invasin: a bacterial integrin-binding protein

artículo científico publicado en 1999

Cultured mammalian cells attach to the invasin protein of Yersinia pseudotuberculosis ⬇️

artículo científico publicado el 1 de septiembre de 1988

DNA gyrase is a host factor required for transposition of Tn5.

artículo científico publicado en 1982

Dancing with the host; flow-dependent bacterial adhesion

artículo científico publicado en 2002

Defining heterogeneity within bacterial populations via single cell approaches

artículo científico publicado en 2016

Delivering dangerous cargoes

artículo científico publicado el 1 de diciembre de 2001

Determinants for thermoinducible cell binding and plasmid-encoded cellular penetration detected in the absence of the Yersinia pseudotuberculosis invasin protein

artículo científico publicado en 1989

Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuole

artículo científico publicado en 2005

Differential effects of integrin alpha chain mutations on invasin and natural ligand interaction

artículo científico publicado en 1998

Discrimination Between Intracellular Uptake and Surface Adhesion of Bacterial Pathogens ⬇️

artículo científico publicado el 17 de mayo de 1991

Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant

artículo científico publicado en 2006

Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction

artículo científico publicado en 2008

Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes

scientific article published on 16 December 2019

E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates

artículo científico publicado en 2010

Efficient uptake of Yersinia pseudotuberculosis via integrin receptors involves a Rac1–Arp 2/3 pathway that bypasses N‐WASP function ⬇️

artículo científico publicado el 1 de noviembre de 2001

Emerging views on integrin signaling via Rac1 during invasin-promoted bacterial uptake

artículo científico publicado en 2005

Endoplasmic Reticulum Tubule Protein Reticulon 4 Associates with the Legionella pneumophila Vacuole and with Translocated Substrate Ceg9.

artículo científico publicado en 2015

Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity

scientific article published on 31 August 2020

Evidence for pore‐forming ability by Legionella pneumophila ⬇️

artículo científico publicado el 1 de enero de 1998

Experimental Evolution of Legionella pneumophila in Mouse Macrophages Leads to Strains with Altered Determinants of Environmental Survival ⬇️

artículo científico publicado el 31 de mayo de 2012

Farewell Stan Stanley Falkow: 1934-2018

scientific article published on 01 July 2018

Formation of a fibrous structure on the surface of Legionella pneumophila associated with exposure of DotH and DotO proteins after intracellular growth

artículo científico publicado en 2001

Formation of the Legionella pneumophila replicative phagosome

artículo científico publicado en 1993

Genetic analysis of bacterial virulence determinants in Bordetella pertussis and the pathogenetic Yersinia

artículo científico publicado en 1985

Genetic analysis of cell invasiveness by Yersinia pseudotuberculosis

artículo científico publicado en 1986

Growth of Legionella pneumophila in Dictyostelium discoideum: a novel system for genetic analysis of host-pathogen interactions

artículo científico publicado en 2000

Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10.

artículo científico publicado en 2007

Host Signal Transduction and Protein Kinases Implicated in Legionella Infection ⬇️

artículo científico publicado el 1 de enero de 2013

IcmF and DotU are required for optimal effector translocation and trafficking of the Legionella pneumophila vacuole

scientific article published on October 2004

IcmR-regulated membrane insertion and efflux by the Legionella pneumophila IcmQ protein

artículo científico publicado en 2003

Identification and Characterization of a Candidate Wolbachia pipientis Type IV Effector That Interacts with the Actin Cytoskeleton

scientific article published on 05 July 2016

Identification of Legionella pneumophila mutants that have aberrant intracellular fates.

artículo científico publicado en 1996

Identification of Legionella pneumophila promoters regulated by the macrophage intracellular environment

scientific article published on 01 August 1993

Identification of Linked Legionella pneumophila Genes Essential for Intracellular Growth and Evasion of the Endocytic Pathway ⬇️

artículo científico publicado el 1 de marzo de 1998

Identification of MrtAB, an ABC transporter specifically required for Yersinia pseudotuberculosis to colonize the mesenteric lymph nodes

artículo científico publicado en 2012

Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells

artículo científico publicado en 1987

Identification of mammalian proteins that collaborate with type III secretion system function: involvement of a chemokine receptor in supporting translocon activity

artículo científico publicado en 2015

Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein ⬇️

artículo científico publicado el 1 de junio de 1990

Inhibition of host cell translation elongation by Legionella pneumophila blocks the host cell unfolded protein response

artículo científico publicado en 2015

Innate Immunity to Intracellular Pathogens: Balancing Microbial Elimination and Inflammation.

artículo científico publicado en 2017

Innate immune recognition of Yersinia pseudotuberculosis type III secretion

artículo científico publicado en 2009

Integrin beta1-chain residues involved in substrate recognition and specificity of binding to invasin

artículo científico publicado en 2000

Interplay Between Antibiotic Resistance and Virulence During Disease Promoted by Multidrug-Resistant Bacteria

artículo científico publicado en 2017

Intracellular growth of Legionella pneumophila in Dictyostelium discoideum, a system for genetic analysis of host-pathogen interactions

artículo científico publicado en 2000

Intracellular replication of Mycobacterium marinum within Dictyostelium discoideum: efficient replication in the absence of host coronin

artículo científico publicado en 2003

Intracellular survival by Legionella.

artículo científico publicado en 1994

Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium ⬇️

artículo científico publicado el 1 de agosto de 1997

Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model

scientific article published on 10 December 2019

Involvement of focal adhesion kinase in invasin-mediated uptake

artículo científico publicado en 1998

Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila

artículo científico publicado en 2016

Iron-Sulfur Cluster Repair Contributes to Yersinia pseudotuberculosis Survival within Deep Tissues

scientific article published on 19 September 2019

Isolation and identification of eukaryotic receptors promoting bacterial internalization

artículo científico publicado en 1994

Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways

artículo científico publicado en 2008

Lasker-Koshland Award to 21st century microbe master

artículo científico publicado en 2008

Legionella pneumophila Dot/Icm translocated substrates: a sum of parts

artículo científico publicado en 2009

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

artículo científico publicado en 1998

Legionella pneumophila EnhC is required for efficient replication in tumour necrosis factor alpha-stimulated macrophages

artículo científico publicado en 2008

Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus

artículo científico publicado en 2001

Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system

artículo científico publicado en 2004

Legionella pneumophila: factors involved in the route and response to an intracellular niche

artículo científico publicado en 1993

Legionnaires' disease: the pore macrophage and the legion of terror within ⬇️

artículo científico publicado el 1 de julio de 1998

Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13

scientific article published on 01 April 1995

LidA, a translocated substrate of the Legionella pneumophila type IV secretion system, interferes with the early secretory pathway

artículo científico publicado en 2005

LnaB: a Legionella pneumophila activator of NF-kappaB.

artículo científico publicado en 2010

Macrophage-induced genes of Legionella pneumophila: protection from reactive intermediates and solute imbalance during intracellular growth

artículo científico publicado en 2002

Macrophages from mice with the restrictive Lgn1 allele exhibit multifactorial resistance to Legionella pneumophila

artículo científico publicado en 2004

Maintenance of vacuole integrity by bacterial pathogens

artículo científico publicado en 2014

Mammalian cell adhesion functions and cellular penetration of enteropathogenic Yersinia species

artículo científico publicado en 1989

Mapping and topographic localization of epitopes of the Yersinia pseudotuberculosis invasin protein

artículo científico publicado en 1991

Master manipulators: an update on Legionella pneumophila Icm/Dot translocated substrates and their host targets

artículo científico publicado en 2014

MavN is a Legionella pneumophila vacuole-associated protein required for efficient iron acquisition during intracellular growth

artículo científico publicado en 2015

Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells

artículo científico publicado en 2006

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion ⬇️

artículo científico publicado el 22 de agosto de 2011

Modulation of the host innate immune and inflammatory response by translocated bacterial proteins

artículo científico publicado en 2015

Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

artículo científico publicado en 1990

Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer.

artículo científico publicado en 2004

Mutations in the cytoplasmic domain of the integrin beta1 chain indicate a role for endocytosis factors in bacterial internalization

artículo científico publicado en 1996

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.

artículo científico publicado en 2006

New Age Strategies To Reconstruct Mucosal Tissue Colonization and Growth in Cell Culture Systems

article

New gene in Escherichia coli K-12 (drpA): does its product play a role in RNA synthesis?

artículo científico publicado en 1985

Non-vertebrate hosts in the analysis of host-pathogen interactions

artículo científico publicado en 2006

One for All, but Not All for One: Social Behavior during Bacterial Diseases

artículo científico publicado en 2018

Pathways for the penetration of enteroinvasive Yersinia into mammalian cells

artículo científico

Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system

artículo científico publicado en 2009

Phagocytosis mediated by Yersinia invasin induces collagenase-1 expression in rabbit synovial fibroblasts through a proinflammatory cascade.

artículo científico publicado en 2001

Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants

artículo científico publicado en 2007

Plague's partners in crime

artículo científico publicado en 2014

Poison Domains Block Transit of Translocated Substrates via the Legionella pneumophila Icm/Dot System ⬇️

artículo científico publicado el 24 de junio de 2013

QnAs with Ralph R. Isberg ⬇️

artículo científico publicado el 7 de enero de 2013

RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics

artículo científico publicado en 2006

Recombinant Soluble Human α3β1Integrin: Purification, Processing, Regulation, and Specific Binding to Laminin-5 and Invasin in a Mutually Exclusive Manner ⬇️

artículo científico publicado el 4 de agosto de 1998

Recombination genes on the Escherichia coli sex factor specific for transposable elements ⬇️

artículo científico publicado el 1 de mayo de 1980

Regulation of Tn5 by the right-repeat proteins: Control at the level of the transposition reaction? ⬇️

artículo científico publicado el 1 de octubre de 1982

Replicon fusions promoted by the inverted repeats of Tn5. The right repeat is an insertion sequence

scientific article published on 01 July 1981

Residues added to the carboxyl terminus of the Yersinia pseudotuberculosis invasin protein interfere with recognition by integrin receptors

artículo científico publicado en 1993

Robust bioengineered 3D functional human intestinal epithelium

artículo científico publicado en 2015

SWIM analysis allows rapid identification of residues involved in invasin-mediated bacterial uptake ⬇️

artículo científico publicado el 28 de abril de 1998

Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).

artículo científico publicado en 2010

Signaling and invasin-promoted uptake via integrin receptors

artículo científico publicado en 2000

Subversion of integrins by enteropathogenic Yersinia

artículo científico publicado en 2001

Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila.

artículo científico publicado en 2006

The DotL protein, a member of the TraG-coupling protein family, is essential for Viability of Legionella pneumophila strain Lp02.

artículo científico publicado en 2005

The E Block motif is associated with Legionella pneumophila translocated substrates ⬇️

artículo científico publicado en 2010

The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage Replication

scientific article published on 11 June 2019

The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation

artículo científico publicado en 2012

The Legionella pneumophila EnhC Protein Interferes with Immunostimulatory Muramyl Peptide Production to Evade Innate Immunity ⬇️

artículo científico publicado el 16 de agosto de 2012

The Legionella pneumophila IcmR protein exhibits chaperone activity for IcmQ by preventing its participation in high-molecular-weight complexes

artículo científico publicado en 2001

The Legionella pneumophila LidA protein: a translocated substrate of the Dot/Icm system associated with maintenance of bacterial integrity

artículo científico publicado en 2003

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

artículo científico publicado en 2008

The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor.

artículo científico publicado en 1991

The amoebal MAP kinase response to Legionella pneumophila is regulated by DupA

artículo científico publicado en 2009

The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines

artículo científico publicado en 2014

The integrin-binding domain of invasin is sufficient to allow bacterial entry into mammalian cells ⬇️

artículo científico publicado el 1 de septiembre de 1992

The interaction of bacteria with mammalian cells

artículo científico publicado el 1 de enero de 1992

The iron-regulated vacuolar Legionella pneumophila MavN protein is a transition-metal transporter

scientific article published on 20 August 2019

The mechanism of phagocytic uptake promoted by invasin-integrin interaction

artículo científico publicado en 1995

The polybasic region of Rac1 modulates bacterial uptake independently of self-association and membrane targeting

artículo científico publicado en 2008

The protein SdhA maintains the integrity of the Legionella-containing vacuole

artículo científico publicado en 2012

The psa locus is responsible for thermoinducible binding of Yersinia pseudotuberculosis to cultured cells.

artículo científico publicado en 1996

The vacuole guard hypothesis: how intravacuolar pathogens fight to maintain the integrity of their beloved home

artículo científico publicado en 2020

Tn5 transposes independently of cointegrate resolution. Evidence for an alternative model for transposition

scientific article published on 01 March 1985

Topologically correct synthetic reconstruction of pathogen social behavior found during Yersinia growth in deep tissue sites

artículo científico publicado en 2020

Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages

artículo científico publicado en 1997

Towards a molecular understanding of human diseases using Dictyostelium discoideum

artículo científico publicado en 2006

Transcriptional regulation of the Yersinia pseudotuberculosis pH6 antigen adhesin by two envelope-associated components

artículo científico publicado en 1997

Transposition of the kanamycin-resistance transposon Tn903.

artículo científico publicado en 1980

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

scientific article published on 01 January 1993

Two mammalian cell internalization strategies used by pathogenic bacteria

artículo científico publicado en 1994

Uptake of enteropathogenic Yersinia by mammalian cells

artículo científico publicado en 1996

Use of Staphylococcus aureus coated with invasin derivatives to assay invasin function

artículo científico publicado en 1994

Use of salt to isolate Legionella pneumophila mutants unable to replicate in macrophages

scientific article published on 01 October 1996

Very late antigen 4-dependent adhesion and costimulation of resting human T cells by the bacterial beta 1 integrin ligand invasin

artículo científico publicado en 1993

Vibrational spectra of cis-dimethyldiazene-d0, -1,1,1-d3, and -d6

article

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission ⬇️

artículo científico publicado el 16 de febrero de 2012

Yersinia pseudotuberculosis disseminates directly from a replicating bacterial pool in the intestine

artículo científico publicado en 2006

Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.

artículo científico publicado en 2005

Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization

scientific article published on 31 August 2009

cis-Dimethyldiazene

article

iMAD, a genetic screening strategy for dissecting complex interactions between a pathogen and its host

artículo científico publicado en 2014

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