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A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost

artículo científico publicado en 2006

A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge

artículo científico publicado en 2010

Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites

artículo científico publicado en 2006

An HSV-1 gD mutant virus as an entry-impaired live virus vaccine

artículo científico publicado en 2008

An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection

artículo científico publicado en 2020

Antibody against Extracellular Vaccinia Virus (EV) Protects Mice through Complement and Fc Receptors ⬇️

artículo científico publicado el 8 de junio de 2011

Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants

artículo científico publicado en 2019

Antibody responses to vaccinia membrane proteins after smallpox vaccination

artículo científico publicado en 2007

Antibody-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein gD Reveal New Targets for Virus Neutralization ⬇️

artículo científico publicado el 30 de noviembre de 2011

Antigenic and mutational analyses of herpes simplex virus glycoprotein B reveal four functional regions

artículo científico publicado en 2007

Bimolecular complementation defines functional regions of Herpes simplex virus gB that are involved with gH/gL as a necessary step leading to cell fusion

artículo científico publicado en 2010

Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion

artículo científico publicado en 2007

Blocking Immune Evasion as a Novel Approach for Prevention and Treatment of Herpes Simplex Virus Infection ⬇️

artículo científico publicado el 1 de diciembre de 2003

Capturing the Herpes Simplex Virus Core Fusion Complex (gB-gH/gL) in an Acidic Environment ⬇️

artículo científico publicado el 20 de abril de 2011

Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB ⬇️

artículo científico publicado el 22 de septiembre de 2010

Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection

artículo científico publicado en 2003

Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D.

artículo científico publicado en 2002

Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model

artículo científico publicado en 2007

Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus

artículo científico publicado en 2006

Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge

artículo científico publicado en 2005

Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus

artículo científico publicado en 2004

Contribution of cysteine residues to the structure and function of herpes simplex virus gH/gL.

artículo científico publicado en 2005

Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections

artículo científico publicado en 2016

Crystal structure of glycoprotein B from herpes simplex virus 1.

artículo científico publicado en 2006

Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL

artículo científico publicado en 2010

Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA

artículo científico publicado en 2002

Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge

artículo científico publicado en 2008

Displacement of the C terminus of herpes simplex virus gD is sufficient to expose the fusion-activating interfaces on gD.

scientific article published on 18 September 2013

Dissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humans

artículo científico publicado en 2014

Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus

artículo científico publicado en 2007

Dual split protein-based fusion assay reveals that mutations to herpes simplex virus (HSV) glycoprotein gB alter the kinetics of cell-cell fusion induced by HSV entry glycoproteins

artículo científico publicado en 2013

Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy

scientific article published on 02 December 2019

Effects of herpes simplex virus on structure and function of nectin-1/HveC.

artículo científico publicado en 2002

Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig ⬇️

artículo científico publicado el 14 de enero de 2011

Engineered disulfide bonds in herpes simplex virus type 1 gD separate receptor binding from fusion initiation and viral entry

artículo científico publicado en 2007

Entry of Herpesviruses into Cells: The Enigma Variations ⬇️

artículo científico publicado el 1 de enero de 2013

Entry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveC

scientific journal article

Epitope mapping of herpes simplex virus type 2 gH/gL defines distinct antigenic sites, including some associated with biological function

artículo científico publicado en 2006

Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R.

artículo científico publicado en 2005

Function of herpes simplex virus type 1 gD mutants with different receptor-binding affinities in virus entry and fusion

artículo científico publicado en 2003

Functional fluorescent protein insertions in herpes simplex virus gB report on gB conformation before and after execution of membrane fusion.

artículo científico publicado en 2014

Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB.

artículo científico publicado en 2009

Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging

artículo científico publicado en 2017

Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1.

artículo científico publicado en 2005

HCMV GrAbs a Mechanism to Escape Neutralization ⬇️

artículo científico publicado el 15 de septiembre de 2011

Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops

artículo científico publicado en 2009

Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry

artículo científico publicado en 2005

Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competition

artículo científico publicado en 2010

Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane

artículo científico publicado en 2007

Herpes simplex virus type 1 evades the effects of antibody and complement in vivo

artículo científico publicado en 2002

Herpes virus fusion and entry: a story with many characters.

artículo científico publicado en 2012

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

artículo científico publicado en 2004

In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa

artículo científico publicado en 2004

Induction of conformational changes at the N-terminus of herpes simplex virus glycoprotein D upon binding to HVEM and nectin-1

artículo científico publicado en 2013

Intranasal nanoemulsion-adjuvanted HSV-2 subunit vaccine is effective as a prophylactic and therapeutic vaccine using the guinea pig model of genital herpes

scientific article published on 09 September 2019

Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b.

artículo científico publicado en 2002

Localization of the interaction site of herpes simplex virus glycoprotein D (gD) on the membrane fusion regulator, gH/gL

scientific article published on 05 August 2020

Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6

artículo científico publicado en 2007

Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B. ⬇️

artículo científico publicado en 2013

Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes

artículo científico publicado en 2006

Mutational Evidence of Internal Fusion Loops in Herpes Simplex Virus Glycoprotein B.

artículo científico publicado en 2008

Mutational evidence of internal fusion loops in herpes simplex virus glycoprotein B

artículo científico publicado en 2007

N-Terminal Mutants of Herpes Simplex Virus Type 2 gH Are Transported without gL but Require gL for Function

N-terminal mutants of herpes simplex virus type 2 gH are transported without gL but require gL for function

artículo científico publicado en 2007

Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs

scientific article published on 26 December 2016

Nectin-1/HveC Mediates herpes simplex virus type 1 entry into primary human sensory neurons and fibroblasts

artículo científico publicado en 2005

Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes

artículo científico publicado en 2019

Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific

artículo científico publicado en 2015

Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene

artículo científico publicado en 2005

Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies

scientific article published on 13 January 2020

Potential nectin-1 binding site on herpes simplex virus glycoprotein d.

artículo científico publicado en 2005

Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Rese

artículo científico publicado en 2017

Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine

artículo científico publicado en 2020

Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions

artículo científico publicado en 2004

Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4.

artículo científico publicado en 2002

Recent insights into the structural characterization of herpes simplex virus fusion protein, gB ⬇️

Regulation of HSV glycoprotein induced cascade of events governing cell-cell fusion

scientific article published on 14 September 2016

Regulation of Herpes Simplex Virus gB-Induced Cell-Cell Fusion by Mutant Forms of gH/gL in the Absence of gD and Cellular Receptors ⬇️

artículo científico publicado el 26 de febrero de 2013

Repertoire of epitopes recognized by serum IgG from humans vaccinated with herpes simplex virus 2 glycoprotein D

artículo científico publicado en 2014

Role of sulfatide in vaccinia virus infection.

artículo científico publicado en 2011

Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1

scientific article published on 03 October 2019

Spatiotemporal changes of the herpes simplex virus entry receptor nectin-1 in murine brain during postnatal development

artículo científico publicado en 2006

Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry

artículo científico publicado en 2003

Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEM

artículo científico publicado en 2006

Structural Basis of Local, pH-Dependent Conformational Changes in Glycoprotein B from Herpes Simplex Virus Type 1 ⬇️

artículo científico publicado el 13 de octubre de 2010

Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

artículo científico publicado en 2011

Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.

artículo científico publicado en 2005

Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM).

artículo científico publicado en 2002

Structure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface

artículo científico publicado en 2003

Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimeras

artículo científico publicado en 2003

Surface Plasmon Resonance Reveals Direct Binding of Herpes Simplex Virus Glycoproteins gH/gL to gD and Locates a gH/gL Binding Site on gD

scientific article published on 17 July 2019

Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses

scientific article published on 13 January 2008

The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane ⬇️

artículo científico publicado en 2017

The Mature Virion of Ectromelia Virus, a Pathogenic Poxvirus, Is Capable of Intrahepatic Spread and Can Serve as a Target for Delayed Therapy ⬇️

artículo científico publicado el 17 de abril de 2013

The Membrane-Proximal Region (MPR) of Herpes Simplex Virus gB Regulates Association of the Fusion Loops with Lipid Membranes ⬇️

artículo científico publicado el 20 de noviembre de 2012

The Myristate Moiety and Amino Terminus of Vaccinia Virus L1 Constitute a Bipartite Functional Region Needed for Entry ⬇️

artículo científico publicado el 7 de marzo de 2012

The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

artículo científico publicado en 2013

The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D.

scientific article published on 20 February 2008

The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination

artículo científico publicado en 2008

The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

artículo científico publicado en 2004

Using a split luciferase assay (SLA) to measure the kinetics of cell-cell fusion mediated by herpes simplex virus glycoproteins

artículo científico publicado en 2015

Using antibodies and mutants to localize the presumptive gH/gL binding site on HSV gD

article

Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs.

artículo científico publicado en 2018

Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans

artículo científico publicado en 2009

Vaccinia virus exhibits cell-type-dependent entry characteristics

artículo científico publicado en 2009

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