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Biofocussed chemoprospecting: An efficient approach for drug discovery.

artículo científico publicado en 2017

Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion, and Relevance to Peptidic Systems.

artículo científico publicado en 2017

Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization

artículo científico publicado en 2018

Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib

artículo científico publicado el 28 de octubre de 2011

Inhibitor binding to mutants of protein kinase A with GGGxxG and GxGxxA glycine-rich loop motifs

artículo científico publicado en 2020

Lysine 156promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA

artículo científico publicado el 15 de agosto de 1997

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

scientific article published on 23 August 2018

Quail cystatin: Isolation and characterisation of a new member of the cystatin family and its hypothetical interaction with cathepsin B

artículo científico publicado el 4 de agosto de 1997

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

artículo científico publicado el 15 de diciembre de 1997

The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro

artículo científico publicado el 25 de octubre de 2010

Two SnRK2-Interacting Calcium Sensor Isoforms Negatively Regulate SnRK2 Activity by Different Mechanisms

scientific article published on 07 November 2019

VX680 Binding in Aurora A: π−π Interactions Involving the Conserved Aromatic Amino Acid of the Flexible Glycine-Rich Loop

artículo científico publicado el 9 de febrero de 2011

p38α MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation

artículo científico publicado el 15 de junio de 2011