Lista de obras -

A Drug-Resistant β-lactamase Variant Changes the Conformation of Its Active Site Proton Shuttle to Alter Substrate Specificity and Inhibitor Potency

artículo científico publicado en 2020

A Standard Numbering Scheme for Class C β-Lactamases

scientific article published on 21 February 2020

Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance

artículo científico publicado en 2020

BLIP-II Employs Differential Hotspot Residues To Bind Structurally Similar Staphylococcus aureus PBP2a and Class A β-Lactamases.

artículo científico publicado en 2017

Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1

artículo científico publicado en 2021

Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from Klebsiella pneumoniae Clinical Isolates

scientific article published on 08 January 2020

High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing

artículo científico publicado en 2020

Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

scientific article published on 25 March 2020

KPC-2 β-lactamase Enables Carbapenem Antibiotic Resistance Through Fast Deacylation of the Covalent Intermediate

artículo científico publicado en 2020

Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

scientific article published on 25 March 2020

Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria.

artículo científico publicado en 2017

Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens

artículo científico publicado en 2015

Structure of the catalytic domain of the colistin resistance enzyme MCR-1.

artículo científico publicado en 2016

Synergistic effects of functionally distinct substitutions in β-lactamase variants shed light on the evolution of bacterial drug resistance

artículo científico publicado en 2018

Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases.

artículo científico publicado en 2017

The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation

artículo científico publicado en 2017

Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of <i>Escherichia coli</i> Producing OXA-48

artículo científico publicado en 2021

Lista de obras de

A Drug-Resistant β-lactamase Variant Changes the Conformation of Its Active Site Proton Shuttle to Alter Substrate Specificity and Inhibitor Potency

A Standard Numbering Scheme for Class C β-Lactamases

Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance

BLIP-II Employs Differential Hotspot Residues To Bind Structurally Similar Staphylococcus aureus PBP2a and Class A β-Lactamases.

Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1

Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from Klebsiella pneumoniae Clinical Isolates

High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing

Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

KPC-2 β-lactamase Enables Carbapenem Antibiotic Resistance Through Fast Deacylation of the Covalent Intermediate

Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria.

Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens

Structure of the catalytic domain of the colistin resistance enzyme MCR-1.

Synergistic effects of functionally distinct substitutions in β-lactamase variants shed light on the evolution of bacterial drug resistance

Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases.

The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation

Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of <i>Escherichia coli</i> Producing OXA-48