Lista de obras -

AIDS/HIV. Host controls of HIV neutralizing antibodies

artículo científico publicado en 2014

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

artículo científico publicado en 2014

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

artículo científico publicado en 2005

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

artículo científico publicado en 2009

B cell responses to HIV-1 infection and vaccination: pathways to preventing infection

artículo científico publicado en 2010

BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance

artículo científico publicado en 2017

Common Tolerance Mechanisms, but Distinct Cross-Reactivities Associated with gp41 and Lipids, Limit Production of HIV-1 Broad Neutralizing Antibodies 2F5 and 4E10 ⬇️

artículo científico publicado el 3 de julio de 2013

Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5

artículo científico publicado en 2019

Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation

artículo científico publicado en 2011

Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

artículo científico publicado en 2021

Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes

artículo científico publicado en 2014

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

artículo científico publicado en 2009

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

artículo científico publicado en 2016

HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

artículo científico publicado en 2012

HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development

artículo científico publicado en 2014

HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence

artículo científico publicado en 2015

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies

artículo científico publicado en 2014

Immune checkpoint modulation enhances HIV-1 antibody induction

artículo científico publicado en 2020

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

artículo científico publicado en 2016

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

artículo científico publicado en 2016

Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses

artículo científico publicado en 2013

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

artículo científico publicado en 2017

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

scientific article published on April 2016

Progress in HIV-1 vaccine development.

artículo científico publicado en 2014

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

artículo científico publicado en 2010

Redemption of autoreactive B cells

artículo científico publicado en 2014

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls

artículo científico publicado en 2011

Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2011

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

artículo científico publicado en 2019

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

article

Lista de obras de

AIDS/HIV. Host controls of HIV neutralizing antibodies

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

B cell responses to HIV-1 infection and vaccination: pathways to preventing infection

BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance

Common Tolerance Mechanisms, but Distinct Cross-Reactivities Associated with gp41 and Lipids, Limit Production of HIV-1 Broad Neutralizing Antibodies 2F5 and 4E10 ⬇️

Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5

Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation

Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development

HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies

Immune checkpoint modulation enhances HIV-1 antibody induction

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

Progress in HIV-1 vaccine development.

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

Redemption of autoreactive B cells

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls

Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template