Lista de obras -

A potential link between phosphate and aging--lessons from Klotho-deficient mice

artículo científico publicado en 2010

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy ⬇️

artículo científico publicado el 2 de septiembre de 2010

Assessment of renal fibrosis with diffusion-weighted MR imaging: study with murine model of unilateral ureteral obstruction

artículo científico publicado en 2010

Association between circulating fibroblast growth factor 21 and mortality in end-stage renal disease

artículo científico publicado en 2017

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

artículo científico publicado en 2007

Characteristics of urinary and serum soluble Klotho protein in patients with different degrees of chronic kidney disease ⬇️

artículo científico publicado el 23 de noviembre de 2012

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis

artículo científico publicado en 2008

FGF23 induces left ventricular hypertrophy

artículo científico publicado en 2011

Fibroblast Growth Factor 23 and Klotho: Physiology and Pathophysiology of an Endocrine Network of Mineral Metabolism ⬇️

artículo científico publicado el 1 de enero de 2013

Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions ⬇️

artículo científico publicado el 15 de septiembre de 2011

Interleukin-36α as a potential biomarker for renal tubular damage induced by dietary phosphate load

scientific article published on 19 March 2020

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells

artículo científico publicado en 2017

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

artículo científico publicado en 2009

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice ⬇️

artículo científico publicado el 5 de enero de 2011

Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways

artículo científico publicado en 2015

Klotho Regulates 14-3-3ζ Monomerization and Binding to the ASK1 Signaling Complex in Response to Oxidative Stress

artículo científico publicado en 2015

Klotho and aging

artículo científico publicado en 2009

Klotho and kidney disease ⬇️

artículo científico publicado el 1 de noviembre de 2010

Klotho and phosphate are modulators of pathologic uremic cardiac remodeling

artículo científico publicado en 2014

Klotho and the Aging Process ⬇️

artículo científico publicado el 1 de junio de 2011

Klotho deficiency causes vascular calcification in chronic kidney disease

artículo científico publicado en 2010

Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective ⬇️

artículo científico publicado el 22 de septiembre de 2010

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

artículo científico publicado en 2010

Life extension factor klotho enhances cognition

artículo científico publicado en 2014

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice

artículo científico publicado en 2015

Molecular Mechanisms Underlying Accelerated Aging by Defects in the FGF23-Klotho System.

artículo científico publicado en 2018

Molecular Regulation of Phosphate Metabolism by Fibroblast Growth Factor-23–Klotho System ⬇️

artículo científico publicado el 1 de marzo de 2011

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

artículo científico publicado en 2007

Phosphate and Klotho

artículo científico publicado en 2011

Pin1 null mice exhibit low bone mass and attenuation of BMP signaling

artículo científico publicado en 2013

Protective Roles of DMP1 in High Phosphate Homeostasis ⬇️

artículo científico publicado el 3 de agosto de 2012

Regulation of fibroblast growth factor-23 signaling by klotho

scientific journal article

Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho

artículo científico publicado en 2009

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

artículo científico publicado en 2010

Role of Klotho in aging, phosphate metabolism, and CKD.

artículo científico publicado en 2011

Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells

artículo científico publicado en 2011

Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

artículo científico publicado en 2014

Suppression of aging in mice by the hormone Klotho

artículo científico publicado en 2005

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

artículo científico publicado en 2006

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging ⬇️

artículo científico publicado el 1 de septiembre de 2010

The FGF23 and Klotho system beyond mineral metabolism.

artículo científico publicado en 2016

The Klotho gene family and the endocrine fibroblast growth factors

artículo científico publicado en 2008

The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study

artículo científico publicado en 2018

The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway

artículo científico publicado en 2022

The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody

artículo científico publicado en 2014

The effect of lanthanum carbonate on calciprotein particles in hemodialysis patients

artículo científico publicado en 2019

The parathyroid is a target organ for FGF23 in rats

scientific journal article

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

artículo científico publicado en 2007

Ultra‐short echo time (UTE) MR imaging of the lung: Comparison between normal and emphysematous lungs in mutant mice ⬇️

artículo científico publicado el 1 de agosto de 2010

Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model

scientific article published on 15 October 2020

α-Klotho protects against oxidative damage in pulmonary epithelia

artículo científico publicado en 2014

αKlotho and vascular calcification: an evolving paradigm

artículo científico publicado en 2014

Lista de obras de

A potential link between phosphate and aging--lessons from Klotho-deficient mice

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy ⬇️

Assessment of renal fibrosis with diffusion-weighted MR imaging: study with murine model of unilateral ureteral obstruction

Association between circulating fibroblast growth factor 21 and mortality in end-stage renal disease

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

Characteristics of urinary and serum soluble Klotho protein in patients with different degrees of chronic kidney disease ⬇️

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis

FGF23 induces left ventricular hypertrophy

Fibroblast Growth Factor 23 and Klotho: Physiology and Pathophysiology of an Endocrine Network of Mineral Metabolism ⬇️

Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions ⬇️

Interleukin-36α as a potential biomarker for renal tubular damage induced by dietary phosphate load

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice ⬇️

Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways

Klotho Regulates 14-3-3ζ Monomerization and Binding to the ASK1 Signaling Complex in Response to Oxidative Stress

Klotho and aging

Klotho and kidney disease ⬇️

Klotho and phosphate are modulators of pathologic uremic cardiac remodeling

Klotho and the Aging Process ⬇️

Klotho deficiency causes vascular calcification in chronic kidney disease

Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective ⬇️

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

Life extension factor klotho enhances cognition

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice

Molecular Mechanisms Underlying Accelerated Aging by Defects in the FGF23-Klotho System.

Molecular Regulation of Phosphate Metabolism by Fibroblast Growth Factor-23–Klotho System ⬇️

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

Phosphate and Klotho

Pin1 null mice exhibit low bone mass and attenuation of BMP signaling

Protective Roles of DMP1 in High Phosphate Homeostasis ⬇️

Regulation of fibroblast growth factor-23 signaling by klotho

Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

Role of Klotho in aging, phosphate metabolism, and CKD.

Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells

Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

Suppression of aging in mice by the hormone Klotho

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging ⬇️

The FGF23 and Klotho system beyond mineral metabolism.

The Klotho gene family and the endocrine fibroblast growth factors

The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study

The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway

The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody

The effect of lanthanum carbonate on calciprotein particles in hemodialysis patients

The parathyroid is a target organ for FGF23 in rats

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

Ultra‐short echo time (UTE) MR imaging of the lung: Comparison between normal and emphysematous lungs in mutant mice ⬇️

Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model

α-Klotho protects against oxidative damage in pulmonary epithelia

αKlotho and vascular calcification: an evolving paradigm