Lista de obras -

97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir

artículo científico publicado en 2017

A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus

artículo científico publicado en 2009

A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus.

artículo científico publicado en 2004

Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes

artículo científico publicado en 2007

Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice

artículo científico publicado en 2008

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model

artículo científico publicado en 2011

Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene

artículo científico publicado en 2002

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice

artículo científico publicado en 2020

Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir

artículo científico publicado en 2014

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

artículo científico publicado en 2006

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child

artículo científico publicado en 2006

Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus

artículo científico publicado en 2003

Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients

artículo científico publicado en 2004

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models

artículo científico publicado en 2018

Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses

artículo científico publicado en 2007

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

artículo científico publicado en 2008

Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada

artículo científico publicado en 2002

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies

artículo científico publicado en 2016

E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient

artículo científico publicado en 2015

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

artículo científico publicado en 2010

Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

artículo científico publicado en 2020

Emergence of an oseltamivir-resistant influenza A/H3N2 virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis

artículo científico publicado en 2013

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

artículo científico publicado en 2009

Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants.

artículo científico publicado en 2014

Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.

artículo científico publicado en 2013

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

artículo científico publicado en 2014

Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period

artículo científico publicado el 1 de octubre de 2003

Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review

artículo científico publicado en 2020

Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations

artículo científico publicado en 2005

Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors

artículo científico publicado en 2011

Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice

artículo científico publicado en 2015

Human metapneumovirus genetic variability, South Africa

artículo científico publicado en 2005

Human metapneumovirus infection in immunocompromised child

artículo científico publicado en 2008

Human metapneumovirus infections in hospitalized children

artículo científico publicado en 2003

Human metapneumovirus, Peru

artículo científico publicado en 2006

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants

artículo científico publicado en 2003

Human metapneumovirus: a new player among respiratory viruses

artículo científico publicado en 2004

Human parechovirus 3 and neonatal infections

artículo científico publicado en 2005

Human parechovirus types 1, 2 and 3 infections in Canada

artículo científico publicado en 2006

Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses.

artículo científico publicado en 2018

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

artículo científico publicado en 2015

Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus

artículo científico publicado en 2011

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

artículo científico publicado en 2006

Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.

artículo científico publicado en 2013

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains

scientific article published on 01 January 2020

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

artículo científico publicado en 2015

In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses

scientific article published on 08 October 2020

In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

artículo científico publicado en 2018

In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site

artículo científico publicado en 2017

Influenza drug resistance

artículo científico

Influenza virus resistance to neuraminidase inhibitors.

artículo científico publicado en 2013

Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs

artículo científico publicado en 2005

Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture

artículo científico publicado en 2009

Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient

artículo científico publicado en 2020

Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center

artículo científico publicado en 2006

New Saffold cardioviruses in 3 children, Canada

artículo científico publicado en 2008

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

artículo científico publicado en 2010

Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses.

artículo científico publicado en 2014

Parenteral peramivir treatment for Oseltamivir-resistant 2009 pandemic influenza A H1N1 viruses

artículo científico publicado en 2011

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors

artículo científico publicado en 2017

Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains.

artículo científico publicado en 2014

Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation

artículo científico publicado en 2010

Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease

artículo científico publicado en 2002

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

article

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child

artículo científico publicado en 2002

Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses

artículo científico publicado en 2011

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein

artículo científico publicado en 2004

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

artículo científico publicado en 2019

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

artículo científico publicado en 2011

The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models

artículo científico publicado en 2016

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.

artículo científico publicado en 2012

The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant

artículo científico publicado en 2010

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

artículo científico publicado en 2016

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors

scientific article published on 16 July 2019

The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus.

artículo científico publicado en 2017

Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation

artículo científico publicado en 2012

Treatment of respiratory virus infections

artículo científico publicado en 2006

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups

artículo científico publicado en 2002

WU polyomavirus in children, Canada

artículo científico publicado en 2007

Whole-genome characterization and genotyping of global WU polyomavirus strains

artículo científico publicado en 2010

Lista de obras de

97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir

A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus

A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus.

Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes

Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model

Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice

Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child

Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus

Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models

Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies

E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

Emergence of an oseltamivir-resistant influenza A/H3N2 virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants.

Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period

Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review

Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations

Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors

Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice

Human metapneumovirus genetic variability, South Africa

Human metapneumovirus infection in immunocompromised child

Human metapneumovirus infections in hospitalized children

Human metapneumovirus, Peru

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants

Human metapneumovirus: a new player among respiratory viruses

Human parechovirus 3 and neonatal infections

Human parechovirus types 1, 2 and 3 infections in Canada

Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses.

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses

In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site

Influenza drug resistance

Influenza virus resistance to neuraminidase inhibitors.

Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs

Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture

Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient

Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center

New Saffold cardioviruses in 3 children, Canada

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses.

Parenteral peramivir treatment for Oseltamivir-resistant 2009 pandemic influenza A H1N1 viruses

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors

Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains.

Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation

Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child

Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.

The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors

The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus.

Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation

Treatment of respiratory virus infections

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups