Filtros de búsqueda

Lista de obras de

3D Chromosomal Landscapes in Hematopoiesis and Immunity

artículo científico publicado en 2019

A Deep Learning Framework for Predicting Response to Therapy in Cancer

scientific article published on 01 December 2019

A critical role for the cytoplasmic tail of pTα in T lymphocyte development

article

A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus

artículo científico publicado en 2006

A new player SETs in myeloid malignancy

artículo científico publicado en 2013

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

artículo científico publicado en 2011

A unique function for cyclin D3 in early B cell development

artículo científico publicado en 2006

AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis

artículo científico publicado en 2018

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression

artículo científico publicado en 2012

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.

artículo científico publicado en 2016

Alternative roles for oxidized mCs and TETs

artículo científico publicado en 2016

Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)

scientific article published on 21 August 2019

Apoptosis, Up the Ante

artículo científico publicado en 2017

Assessing quality and completeness of human transcriptional regulatory pathways on a genome-wide scale

artículo científico publicado en 2011

Author Correction: The bone marrow microenvironment at single-cell resolution

artículo científico publicado en 2019

Author Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

artículo científico publicado en 2020

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

artículo científico publicado en 2017

Beating the Clock in T-cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2016

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

artículo científico publicado en 2009

CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation

scientific article published on 03 September 2020

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

artículo científico publicado en 2015

CXCR4 signaling directs Igk recombination and the molecular mechanisms of late B lymphopoiesis

artículo científico publicado en 2019

Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function

artículo científico publicado en 2015

Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21

scientific article published on 26 April 2019

Cell-by-Cell Deconstruction of Stem Cell Niches

artículo científico publicado en 2020

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

artículo científico publicado en 2020

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms

artículo científico publicado en 2015

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.

artículo científico publicado en 2017

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

artículo científico publicado en 2014

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes

artículo científico publicado en 2014

Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

artículo científico publicado en 2008

Cyclin C is a haploinsufficient tumour suppressor

artículo científico publicado en 2014

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

artículo científico publicado en 2014

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

artículo científico publicado en 2013

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

artículo científico publicado en 2016

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells

artículo científico publicado en 2013

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

artículo científico publicado en 2012

Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages

artículo científico publicado en 2005

Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential

artículo científico publicado en 2003

Emerging concepts of epigenetic dysregulation in hematological malignancies

artículo científico publicado en 2016

Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond

artículo científico

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis

artículo científico publicado en 2013

Energy addiction and lymphocyte differentiation: a new role for the liver kinase B1 kinase

artículo científico publicado en 2010

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

scientific article published on 01 January 2020

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy

artículo científico publicado en 2015

Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2020

FBXW7 inactivation in a BrafV600E -driven mouse model leads to melanoma development

artículo científico publicado en 2017

FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

artículo científico publicado en 2015

Fingerprinting Acute Leukemia: DNA Methylation Profiling of B-Acute Lymphoblastic Leukemia ⬇️

artículo científico publicado el 1 de noviembre de 2012

From fly wings to targeted cancer therapies: a centennial for notch signaling

artículo científico publicado en 2014

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

artículo científico publicado en 2008

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

artículo científico publicado en 2012

Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia

artículo científico publicado en 2014

Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma

artículo científico publicado en 2016

Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ

scientific article published on 01 April 2020

Harald von Boehmer 1942-2018

scientific article published on 01 September 2018

Hedgehog and hematopoietic stem cell differentiation: don't believe the hype!

artículo científico publicado en 2009

Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus

artículo científico publicado en 2006

Hedgehog signaling is dispensable for adult hematopoietic stem cell function

artículo científico publicado en 2009

Hes1 expression and CYLD repression are essential events downstream of Notch1 in T-cell leukemia.

artículo científico

Hexamethylene bisacetamide as a treatment for T-cell leukemia (T-ALL).

artículo científico publicado en 2007

HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking

artículo científico publicado en 2017

Higher-Order Looping and Nuclear Organization of Tcra Facilitate Targeted RAG Cleavage and Regulated Rearrangement in Recombination Centers ⬇️

artículo científico publicado el 14 de febrero de 2013

Hijacking T cell differentiation: new insights in TLX function in T-ALL.

artículo científico publicado en 2012

Immune-Based Therapies in Acute Leukemia

artículo científico publicado en 2019

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

artículo científico publicado en 2019

In vivo mapping of notch pathway activity in normal and stress hematopoiesis

artículo científico publicado en 2013

Leukemia-on-a-chip: Dissecting the chemoresistance mechanisms in B cell acute lymphoblastic leukemia bone marrow niche

artículo científico publicado en 2020

Limited miR-17-92 overexpression drives hematologic malignancies

artículo científico publicado en 2014

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining

artículo científico publicado en 2019

Mapping and targeting of the leukemic microenvironment

scientific article published on 01 February 2020

Mechanisms of epigenetic regulation of leukemia onset and progression

artículo científico publicado en 2013

Molecular pathogenesis of T-cell leukaemia and lymphoma

scientific article published on May 2008

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.

artículo científico publicado en 2016

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia

artículo científico publicado en 2015

Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche

scientific article published on 17 May 2018

Notch pathway activation targets AML-initiating cell homeostasis and differentiation

artículo científico publicado en 2013

Notch signaling: switching an oncogene to a tumor suppressor.

scientific article published on 07 March 2014

Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.

artículo científico publicado en 2006

Notches, NFkappaBs and the making of T cell leukemia.

artículo científico publicado en 2007

On Epigenetic Plasticity and Genome Topology

artículo científico publicado en 2020

On the brink of becoming a T cell.

artículo científico publicado en 2002

Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

artículo científico publicado en 2011

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia

scientific article published on 23 July 2018

Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex

artículo científico publicado en 2017

Positive selection by the pre-TCR yields mature CD8+ T cells

artículo científico publicado en 2002

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

artículo científico publicado en 2020

Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development

artículo científico publicado en 2004

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

artículo científico publicado en 2014

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

artículo científico publicado en 2013

Publisher Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 07 January 2020

RNA Splicing and Cancer

scientific article published on 17 May 2020

RNA-binding proteins come out of the shadows

artículo científico publicado en 2010

RNA-binding proteins, the guardians of the marginal zone

artículo científico publicado en 2017

Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition

artículo científico publicado en 2020

Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.

artículo científico publicado en 2006

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.

artículo científico publicado en 2013

Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex

artículo científico publicado en 2010

Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system ⬇️

artículo científico publicado el 18 de febrero de 2012

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

artículo científico publicado en 2008

Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid

scholarly article

Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system

artículo científico publicado en 2012

Regulation of stem cell function by protein ubiquitylation

artículo científico publicado en 2014

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

scientific article published on 17 October 2016

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

scientific journal article

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.

artículo científico publicado en 2017

Role of dysregulated cytokine signaling and bacterial triggers in the pathogenesis of Cutaneous T Cell Lymphoma

artículo científico publicado en 2017

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2 ⬇️

artículo científico publicado en 2021

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

artículo científico publicado en 2015

STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.

artículo científico publicado en 2014

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia

artículo científico publicado en 2018

Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia

artículo científico publicado en 2021

Splicing the innate immune signalling in leukaemia

scientific article published on 01 May 2019

Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries

artículo científico publicado en 2018

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.

artículo científico publicado en 2011

TET family proteins and their role in stem cell differentiation and transformation.

artículo científico publicado en 2011

TET1 is a tumor suppressor of hematopoietic malignancy

artículo científico publicado en 2015

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis

artículo científico publicado en 2018

Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment

scientific article published on 02 May 2019

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

artículo científico publicado en 2019

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

artículo científico publicado en 2006

Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells

artículo científico publicado en 2012

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

artículo científico publicado en 2017

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

scientific journal article

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

scientific journal article

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis

artículo científico publicado en 2015

The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells

artículo científico publicado en 2006

The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation

scientific article published on 12 August 2019

The Impact of DNA Methylation in Hematopoietic Malignancies

artículo científico publicado en 2016

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

artículo científico publicado en 2010

The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage

scientific article published on January 2013

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

artículo científico publicado en 2007

The Taming of the NF-κB: PP4R1 Navigates while PP4c Dephosphorylates ⬇️

artículo científico publicado el 19 de octubre de 2012

The bone marrow microenvironment at single-cell resolution

scientific article published on 10 April 2019

The effect of chromatin states on cancer: big data lead the way

artículo científico publicado en 2018

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

scientific article published on 25 November 2019

The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells

artículo científico publicado en 2015

The pre-BCR to the rescue: therapeutic targeting of pre-B cell ALL.

artículo científico publicado en 2015

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

artículo científico publicado en 2013

The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells

artículo científico publicado en 2016

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

scientific article published on 26 November 2019

Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.

artículo científico publicado en 2012

Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia

artículo científico publicado en 2020

Thymic selection revisited: how essential is it?

artículo científico publicado en 2003

Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene

article

U.S. Biomedical Research Needs More Immigrant Scientists, Not Fewer!

scientific article published on 01 September 2020

Vitamin C in Stem Cell Reprogramming and Cancer

scientific article published on 30 April 2018

lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets

artículo científico publicado en 2017

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda