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Capturing Aβ42 aggregation in the cell

artículo científico publicado en 2019

Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity

artículo científico publicado en 2022

Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers

scientific article published on 02 August 2019

Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine

artículo científico publicado en 2020

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

article

Nanoscale Discrimination between Toxic and Nontoxic Protein Misfolded Oligomers with Tip-Enhanced Raman Spectroscopy

article

Probing conformational changes of monomeric transthyretin with second derivative fluorescence

artículo científico publicado en 2019

Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies

scientific article published on 14 May 2019

Soluble Prion Peptide 107-120 Protects Neuroblastoma SH-SY5Y Cells against Oligomers Associated with Alzheimer's Disease

artículo científico publicado en 2020

Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic

artículo científico publicado en 2022

Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity

artículo científico publicado en 2018

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

artículo científico publicado en 2017

Structural differences between toxic and nontoxic HypF-N oligomers

article

The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure

scientific article published on 05 July 2019

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

artículo científico publicado en 2021

Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers

artículo científico publicado en 2020

Trodusquemine enhances Aβ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

scientific article published in Nature Communications

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