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A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury

artículo científico publicado en 2007

All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers

artículo científico publicado en 2012

Alzheimer's disease: which type of amyloid-preventing drug agents to employ?

artículo científico publicado en 2013

Alzheimer's β-Amyloid All-D-Enantiomers and Native All-L-Enantiomers Exhibit Similar Pore Structures in Lipid Bilayers: Atomic Force Microscopy

Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts

artículo científico publicado en 2017

Antimicrobial properties of amyloid peptides

artículo científico publicado en 2011

Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link

artículo científico publicado en 2011

Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies

artículo científico publicado en 2010

Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology

artículo científico publicado en 2012

Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: lab-on-a-chip system for lipid membranes and ion channels

artículo científico publicado en 2007

Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity

artículo científico publicado en 2006

Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels.

artículo científico publicado en 2016

DNA Hydrogel with Aptamer-Toehold-Based Recognition, Cloaking, and Decloaking of Circulating Tumor Cells for Live Cell Analysis.

artículo científico publicado en 2017

DNA Nanotweezers and Graphene Transistor Enable Label-Free Genotyping

artículo científico publicado en 2018

DNA Zippers and Regenerative Nano-Gates

DNA zipper-based tweezers

artículo científico publicado en 2011

Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs

artículo científico publicado en 2014

Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations

artículo científico publicado en 2012

Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment

artículo científico publicado en 2013

Generating Cyan Fluorescence with De Novo Tripeptides: An In Vitro Mutation Study on the Role of Single Amino Acid Residues and Their Sequence

scientific article published on 29 July 2019

Gold-Embedded Hollow Silica Nanogolf Balls for Imaging and Photothermal Therapy

artículo científico publicado en 2017

Graphite-Templated Amyloid Nanostructures Formed by a Potential Pentapeptide Inhibitor for Alzheimer's Disease: A Combined Study of Real-Time Atomic Force Microscopy and Molecular Dynamics Simulations

artículo científico publicado en 2017

Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress

artículo científico

High performance, LED powered, waveguide based total internal reflection microscopy

artículo científico publicado en 2013

Hollow Disc and Sphere-Shaped Particles from Red Blood Cell Templates

Integrated sensors and BioMEMS for in vitro high throughput biomarkers and drug discovery

Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies

artículo científico publicado en 2015

K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis

artículo científico publicado en 2009

Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System

artículo científico publicado en 2020

Magnetic targeting of nanoparticles across the intact blood-brain barrier

artículo científico publicado en 2012

Measuring localized redox enzyme electron transfer in a live cell with conducting atomic force microscopy

artículo científico publicado en 2014

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane

artículo científico publicado en 2012

Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

scientific article published on December 2009

Modeling Alzheimer's Ion Channel Structures in Lipid Bilayers Formed by D- and L-Enantiomers of Beta-Amyloid (1-42) Peptide

Modeling Ion-Permeable β-Amyloid (Aβ) Barrels in the Lipid Bilayer

Modeling Variants of Alzheimer's Ion Channels in the Lipid Bilayer formed by an Aggregation-Intermediate β-Hairpin and E22Δ Mutant

Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels

artículo científico publicado en 2008

Multidimensional Atomic Force Microscopy: A Versatile Novel Technology for Nanopharmacology Research

artículo científico publicado el 19 de octubre de 2010

Multidimensional atomic force microscopy for drug discovery: a versatile tool for defining targets, designing therapeutics and monitoring their efficacy

scientific article published on 26 April 2009

Mutant SOD1 forms ion channel: implications for ALS pathophysiology

artículo científico publicado en 2011

Nanobiotechnology for neurodegenerative and protein-misfolding diseases

Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing

artículo científico publicado en 2006

New structures help the modeling of toxic amyloidbeta ion channels

artículo científico publicado en 2008

Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action

artículo científico publicado en 2016

Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels

artículo científico publicado en 2006

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

artículo científico publicado en 2011

Potential role of atomic force microscopy in systems biology

artículo científico publicado en 2011

Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions

artículo científico publicado en 2012

Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin

artículo científico publicado en 2008

Scope of atomic force microscopy in the advancement of nanomedicine

artículo científico publicado en 2010

Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics

artículo científico publicado en 2016

Structural convergence among diverse, toxic beta-sheet ion channels

artículo científico publicado en 2010

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy

artículo científico

Structure–Function Studies of Amyloid Pores in Alzheimer’s Disease as a Case Example of Neurodegenerative Diseases

Sub-nanowatt microfluidic single-cell calorimetry

artículo científico publicado en 2020

The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

artículo científico publicado en 2017

Transmembrane β-Barrel Topology Model for Alzheimer's β-Amyloid (Aβ) Ion Channels

article published in 2011

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

artículo científico publicado en 2010

Tunable and Regenerative DNA Zipper Based Spring

article

β-Barrel topology of Alzheimer's β-amyloid ion channels

artículo científico publicado en 2010