Lista de obras -

A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation

artículo científico publicado en 2017

A method for assaying deubiquitinating enzymes ⬇️

artículo científico publicado el 20 de julio de 1998

A novel adipokine CTRP1 stimulates aldosterone production

artículo científico publicado en 2008

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

artículo científico

Adiponectin is a negative regulator of NK cell cytotoxicity.

artículo científico publicado en 2006

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

artículo científico publicado en 2009

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

artículo científico publicado en 2018

Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells

artículo científico publicado en 2007

Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer ⬇️

artículo científico publicado el 26 de agosto de 2010

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

artículo científico publicado en 2009

Carabrol suppresses LPS-induced nitric oxide synthase expression by inactivation of p38 and JNK via inhibition of I-kappaBalpha degradation in RAW 264.7 cells

artículo científico

DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis

artículo científico publicado en 2011

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

artículo científico publicado en 2014

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

artículo científico publicado en 2014

EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex

artículo científico publicado en 2012

Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice.

artículo científico publicado en 2016

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

artículo científico publicado en 2009

Emerging roles of orphan nuclear receptors in cancer

artículo científico publicado en 2013

Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases

artículo científico publicado en 2020

Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling

artículo científico publicado en 2005

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

artículo científico publicado en 2012

Epigenetic Control of Autophagy: Nuclear Events Gain More Attention

artículo científico publicado en 2017

Epigenetic and transcriptional regulation of autophagy

artículo científico publicado en 2016

Epigenetic regulation of the potential tumor suppressor gene, hLHX6.1, in human cervical cancer

artículo científico publicado en 2011

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

artículo científico publicado en 2007

High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction

artículo científico publicado en 2003

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

artículo científico publicado en 2016

ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

artículo científico publicado en 2009

ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin

artículo científico publicado en 2005

ISG15, not just another ubiquitin-like protein

artículo científico publicado en 2003

Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene.

artículo científico publicado en 2010

Increase in CIP2A expression is associated with doxorubicin resistance.

artículo científico

Increased expression of the F(1)F(o) ATP synthase in response to iron in heart mitochondria

artículo científico publicado en 2008

Inhibition of LSD1 phosphorylation alleviates colitis symptoms induced by dextran sulfate sodium

scientific article published on 22 April 2020

Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death

artículo científico publicado en 2020

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

artículo científico publicado en 2016

Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D.

artículo científico publicado en 2014

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation ⬇️

artículo científico publicado en 2004

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

artículo científico publicado en 2012

Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

artículo científico publicado en 2007

Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1.

artículo científico publicado en 2017

Negative regulation of hypoxic responses via induced Reptin methylation.

artículo científico publicado en 2010

Nuclear receptors and coregulators in inflammation and cancer

artículo científico publicado en 2008

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

artículo científico publicado en 2015

Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway

artículo científico publicado en 2013

Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors

artículo científico publicado en 2017

PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response

artículo científico publicado en 2018

Pontin-deficiency causes senescence in fibroblast cells and epidermal keratinocytes but induces apoptosis in cancer cells

artículo científico publicado en 2020

Protein ISGylation modulates the JAK-STAT signaling pathway

artículo científico publicado en 2003

Purification and Characterization of Protease Ci, a Cytoplasmic Metalloendoprotease in Escherichia coli

artículo científico publicado en 1995

RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer

artículo científico publicado en 2010

RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network.

artículo científico publicado en 2017

RORα2 requires LSD1 to enhance tumor progression in breast cancer.

artículo científico publicado en 2017

Regulation of HIF-1α stability by lysine methylation

artículo científico publicado en 2016

Regulation of mIκBNS stability through PEST-mediated degradation by proteasome.

artículo científico publicado en 2014

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

artículo científico publicado en 2004

Roles of Mis18α in epigenetic regulation of centromeric chromatin and CENP-A loading

scientific journal article

Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis

artículo científico publicado en 2006

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

artículo científico publicado en 2015

SK-126, a synthetic compound, regulates the production of inflammatory cytokines induced by LPS in antigen-presenting cells

artículo científico publicado en 2007

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

artículo científico publicado en 2007

SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination

artículo científico publicado en 2006

SUMOylation code in cancer development and metastasis.

artículo científico publicado en 2006

SUMOylation of RORalpha potentiates transcriptional activation function.

artículo científico publicado en 2008

SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells

artículo científico publicado en 2007

Serum starvation induces G1 arrest through suppression of Skp2-CDK2 and CDK4 in SK-OV-3 cells

artículo científico publicado en 2008

Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes

artículo científico publicado en 2016

Small ubiquitin-like modifiers in cellular malignancy and metastasis

artículo científico publicado en 2009

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

artículo científico publicado en 2015

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

artículo científico publicado en 2010

The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

artículo científico publicado en 2012

The role of ADCYAP1, adenylate cyclase activating polypeptide 1, as a methylation biomarker for the early detection of cervical cancer

artículo científico publicado en 2011

Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.

artículo científico publicado en 2006

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

artículo científico publicado en 2002

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

artículo científico publicado en 2006

ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation

scientific article published on 01 December 2018

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

artículo científico publicado en 2006

Versatile protein tag, SUMO: its enzymology and biological function

artículo científico publicado en 2002

βTrCP-mediated ubiquitylation regulates protein stability of Mis18β in a cell cycle-dependent manner.

artículo científico publicado en 2013

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de

A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation

A method for assaying deubiquitinating enzymes ⬇️

A novel adipokine CTRP1 stimulates aldosterone production

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

Adiponectin is a negative regulator of NK cell cytotoxicity.

Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation.

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells

Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer ⬇️

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

Carabrol suppresses LPS-induced nitric oxide synthase expression by inactivation of p38 and JNK via inhibition of I-kappaBalpha degradation in RAW 264.7 cells

DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis

Dephosphorylation of CCAAT/enhancer-binding protein β by protein phosphatase 2A containing B56δ is required at the early time of adipogenesis.

Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex

Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice.

Elevation of intracellular cyclic AMP inhibits NF-kappaB-mediated thymosin beta4 expression in melanoma cells

Emerging roles of orphan nuclear receptors in cancer

Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases

Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

Epigenetic Control of Autophagy: Nuclear Events Gain More Attention

Epigenetic and transcriptional regulation of autophagy

Epigenetic regulation of the potential tumor suppressor gene, hLHX6.1, in human cervical cancer

Expression of human NDRG2 by myeloid dendritic cells inhibits down-regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity.

High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction

IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells

ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin

ISG15, not just another ubiquitin-like protein

Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene.

Increase in CIP2A expression is associated with doxorubicin resistance.

Increased expression of the F(1)F(o) ATP synthase in response to iron in heart mitochondria

Inhibition of LSD1 phosphorylation alleviates colitis symptoms induced by dextran sulfate sodium

Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death

Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.

Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D.

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation ⬇️

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1.

Negative regulation of hypoxic responses via induced Reptin methylation.

Nuclear receptors and coregulators in inflammation and cancer

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP.

Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway

Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors

PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response

Pontin-deficiency causes senescence in fibroblast cells and epidermal keratinocytes but induces apoptosis in cancer cells

Protein ISGylation modulates the JAK-STAT signaling pathway

Purification and Characterization of Protease Ci, a Cytoplasmic Metalloendoprotease in Escherichia coli

RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer

RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network.

RORα2 requires LSD1 to enhance tumor progression in breast cancer.

Regulation of HIF-1α stability by lysine methylation

Regulation of mIκBNS stability through PEST-mediated degradation by proteasome.

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

Roles of Mis18α in epigenetic regulation of centromeric chromatin and CENP-A loading

Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity.

SK-126, a synthetic compound, regulates the production of inflammatory cytokines induced by LPS in antigen-presenting cells

SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination

SUMOylation code in cancer development and metastasis.

SUMOylation of RORalpha potentiates transcriptional activation function.

SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells

Serum starvation induces G1 arrest through suppression of Skp2-CDK2 and CDK4 in SK-OV-3 cells

Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes

Small ubiquitin-like modifiers in cellular malignancy and metastasis

TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

The role of ADCYAP1, adenylate cyclase activating polypeptide 1, as a methylation biomarker for the early detection of cervical cancer

Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

Versatile protein tag, SUMO: its enzymology and biological function

βTrCP-mediated ubiquitylation regulates protein stability of Mis18β in a cell cycle-dependent manner.